Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
RB1	ARLFLDHDN	CENTRAL_NERVOUS_SYSTEM	333	p.K341fs	c.1021_1022delAA	Frame_Shift_Del	1	0.11	42MGBA	N	2	0	0	N
RB1	ARLFLIMIK	LUNG	333	p.L337fs	c.1011_1011delG	Frame_Shift_Del	3	0.11	COLO668	Y	2	10	0	N
RB1	DARLFLIMI	LUNG	332	p.L337fs	c.1011_1011delG	Frame_Shift_Del	3	0.11	COLO668	Y	9	10	0	N
RB1	DLDARLFLI	LUNG	330	p.L337fs	c.1011_1011delG	Frame_Shift_Del	1	0.11	COLO668	Y	11	11	0	N
RB1	DQPSENLIP	LUNG	394	p.I401fs	c.1202_1202delT	Frame_Shift_Del	1	0.11	HCC33	N	0	0	0	N
RB1	ENLIPILTT	LUNG	398	p.I401fs	c.1202_1202delT	Frame_Shift_Del	5	0.11	HCC33	N	0	0	0	Y
RB1	ERLLSEHPN	LUNG	667	p.P674fs	c.2022_2022delA	Frame_Shift_Del	1	0.11	CORL51	N	1	0	0	N
RB1	EVKNVYFKI	ENDOMETRIUM	287	p.K294fs	c.880_880delA	Frame_Shift_Del	1	0.11	ISHIKAWAHERAKLIO02ER	Y	6	11	0	N
RB1	FLDHDNSSD	CENTRAL_NERVOUS_SYSTEM	336	p.K341fs	c.1021_1022delAA	Frame_Shift_Del	4	0.11	42MGBA	N	2	0	0	N
RB1	FLIMIKLFR	LUNG	336	p.L337fs	c.1011_1011delG	Frame_Shift_Del	5	0.11	COLO668	N	9	0	38	N
RB1	IMIKLFRLI	LUNG	338	p.L337fs	c.1011_1011delG	Frame_Shift_Del	5	0.11	COLO668	N	15	0	16	N
RB1	KNVYFKILY	ENDOMETRIUM	289	p.K294fs	c.880_880delA	Frame_Shift_Del	3	0.11	ISHIKAWAHERAKLIO02ER	N	7	0	0	N
RB1	LDARLFLIM	LUNG	331	p.L337fs	c.1011_1011delG	Frame_Shift_Del	2	0.11	COLO668	N	8	0	0	N
RB1	LFLDHDNSS	CENTRAL_NERVOUS_SYSTEM	335	p.K341fs	c.1021_1022delAA	Frame_Shift_Del	3	0.11	42MGBA	N	0	0	8	N
RB1	LFLIMIKLF	LUNG	335	p.L337fs	c.1011_1011delG	Frame_Shift_Del	5	0.11	COLO668	N	7	0	14	N
RB1	LIMIKLFRL	LUNG	337	p.L337fs	c.1011_1011delG	Frame_Shift_Del	5	0.11	COLO668	N	15	0	24	N
RB1	LIPILTTAQ	LUNG	400	p.I401fs	c.1202_1202delT	Frame_Shift_Del	5	0.11	HCC33	N	0	0	20	N
RB1	LSLFYKKCI	SOFT_TISSUE	647	p.K652fs	c.1954_1954delA	Frame_Shift_Del	2	0.11	SKUT1	N	11	0	12	N
RB1	MIKLFRLIL	LUNG	339	p.L337fs	c.1011_1011delG	Frame_Shift_Del	5	0.11	COLO668	Y	10	9	21	N
RB1	NLIPILTTA	LUNG	399	p.I401fs	c.1202_1202delT	Frame_Shift_Del	5	0.11	HCC33	Y	4	11	0	N
RB1	NVYFKILYL	ENDOMETRIUM	290	p.K294fs	c.880_880delA	Frame_Shift_Del	4	0.11	ISHIKAWAHERAKLIO02ER	Y	17	9	0	N
RB1	PSENLIPIL	LUNG	396	p.I401fs	c.1202_1202delT	Frame_Shift_Del	3	0.11	HCC33	N	0	0	0	N
RB1	QPSENLIPI	LUNG	395	p.I401fs	c.1202_1202delT	Frame_Shift_Del	2	0.11	HCC33	Y	14	11	0	N
RB1	RLFLDHDNS	CENTRAL_NERVOUS_SYSTEM	334	p.K341fs	c.1021_1022delAA	Frame_Shift_Del	2	0.11	42MGBA	N	2	0	0	N
RB1	RLFLIMIKL	LUNG	334	p.L337fs	c.1011_1011delG	Frame_Shift_Del	4	0.11	COLO668	Y	23	9	0	N
RB1	SENLIPILT	LUNG	397	p.I401fs	c.1202_1202delT	Frame_Shift_Del	4	0.11	HCC33	N	6	0	0	N
RB1	SLFYKKCIG	SOFT_TISSUE	648	p.K652fs	c.1954_1954delA	Frame_Shift_Del	3	0.11	SKUT1	N	0	0	0	N
RB1	SLSLFYKKC	SOFT_TISSUE	646	p.K652fs	c.1954_1954delA	Frame_Shift_Del	1	0.11	SKUT1	Y	5	9	0	N
RB1	VKNVYFKIL	ENDOMETRIUM	288	p.K294fs	c.880_880delA	Frame_Shift_Del	2	0.11	ISHIKAWAHERAKLIO02ER	N	8	0	2	N
RB1	VYFKILYLL	ENDOMETRIUM	291	p.K294fs	c.880_880delA	Frame_Shift_Del	5	0.11	ISHIKAWAHERAKLIO02ER	Y	14	9	6	N
RB1	CGWSIGRLY	ENDOMETRIUM	83	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	6	0	0	N
RB1	CGWSIGRLY	OVARY	83	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	6	0	0	N
RB1	DHVRESLVN	ENDOMETRIUM	68	p.R71fs	c.211_212delAG	Frame_Shift_Del	4	0.22	COLO684	N	1	0	0	N
RB1	DHVRESLVN	OVARY	68	p.R71fs	c.211_212delAG	Frame_Shift_Del	4	0.22	COLO704	N	1	0	0	N
RB1	EKGTVGNLY	ENDOMETRIUM	94	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	3	0	0	N
RB1	EKGTVGNLY	OVARY	94	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	3	0	0	N
RB1	ESFICGWSI	ENDOMETRIUM	79	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	6	0	0	N
RB1	ESFICGWSI	OVARY	79	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	6	0	0	N
RB1	ESLVNLGES	ENDOMETRIUM	72	p.R71fs	c.211_212delAG	Frame_Shift_Del	4	0.22	COLO684	N	2	0	0	N
RB1	ESLVNLGES	OVARY	72	p.R71fs	c.211_212delAG	Frame_Shift_Del	4	0.22	COLO704	N	2	0	0	N
RB1	FICGWSIGR	ENDOMETRIUM	81	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	8	0	3	N
RB1	FICGWSIGR	OVARY	81	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	8	0	3	N
RB1	GESFICGWS	ENDOMETRIUM	78	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	4	0	0	N
RB1	GESFICGWS	OVARY	78	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	4	0	0	N
RB1	GNLYLYCSS	ENDOMETRIUM	99	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	1	0	0	N
RB1	GNLYLYCSS	OVARY	99	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	1	0	0	N
RB1	GRLYSKEKG	ENDOMETRIUM	88	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	1	0	0	N
RB1	GRLYSKEKG	OVARY	88	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	1	0	0	N
RB1	GTVGNLYLY	ENDOMETRIUM	96	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	Y	8	13	0	N
RB1	GTVGNLYLY	OVARY	96	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	Y	8	13	0	N
RB1	GWSIGRLYS	ENDOMETRIUM	84	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	0	0	0	N
RB1	GWSIGRLYS	OVARY	84	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	0	0	0	N
RB1	HVRESLVNL	ENDOMETRIUM	69	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	Y	7	11	0	N
RB1	HVRESLVNL	OVARY	69	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	Y	7	11	0	N
RB1	ICGWSIGRL	ENDOMETRIUM	82	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	6	0	0	N
RB1	ICGWSIGRL	OVARY	82	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	6	0	0	N
RB1	IGRLYSKEK	ENDOMETRIUM	87	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	0	0	2	N
RB1	IGRLYSKEK	OVARY	87	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	0	0	2	N
RB1	IPDHVRESL	ENDOMETRIUM	66	p.R71fs	c.211_212delAG	Frame_Shift_Del	2	0.22	COLO684	Y	17	10	0	Y
RB1	IPDHVRESL	OVARY	66	p.R71fs	c.211_212delAG	Frame_Shift_Del	2	0.22	COLO704	Y	17	10	0	Y
RB1	KEKGTVGNL	ENDOMETRIUM	93	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	Y	9	13	0	N
RB1	KEKGTVGNL	OVARY	93	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	Y	9	13	0	N
RB1	KGTVGNLYL	ENDOMETRIUM	95	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	10	0	0	N
RB1	KGTVGNLYL	OVARY	95	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	10	0	0	N
RB1	KIPDHVRES	ENDOMETRIUM	65	p.R71fs	c.211_212delAG	Frame_Shift_Del	1	0.22	COLO684	N	1	0	0	Y
RB1	KIPDHVRES	OVARY	65	p.R71fs	c.211_212delAG	Frame_Shift_Del	1	0.22	COLO704	N	1	0	0	Y
RB1	LGESFICGW	ENDOMETRIUM	77	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	3	0	0	N
RB1	LGESFICGW	OVARY	77	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	3	0	0	N
RB1	LVNLGESFI	ENDOMETRIUM	74	p.R71fs	c.211_212delAG	Frame_Shift_Del	3	0.22	COLO684	Y	9	10	3	N
RB1	LVNLGESFI	OVARY	74	p.R71fs	c.211_212delAG	Frame_Shift_Del	3	0.22	COLO704	Y	9	10	3	N
RB1	LYSKEKGTV	ENDOMETRIUM	90	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	3	0	5	N
RB1	LYSKEKGTV	OVARY	90	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	3	0	5	N
RB1	NLGESFICG	ENDOMETRIUM	76	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	0	0	0	N
RB1	NLGESFICG	OVARY	76	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	0	0	0	N
RB1	PDHVRESLV	ENDOMETRIUM	67	p.R71fs	c.211_212delAG	Frame_Shift_Del	3	0.22	COLO684	N	1	0	0	N
RB1	PDHVRESLV	OVARY	67	p.R71fs	c.211_212delAG	Frame_Shift_Del	3	0.22	COLO704	N	1	0	0	N
RB1	RESLVNLGE	ENDOMETRIUM	71	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	0	0	0	N
RB1	RESLVNLGE	OVARY	71	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	0	0	0	N
RB1	RLYSKEKGT	ENDOMETRIUM	89	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	4	0	0	Y
RB1	RLYSKEKGT	OVARY	89	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	4	0	0	Y
RB1	SFICGWSIG	ENDOMETRIUM	80	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	0	0	0	N
RB1	SFICGWSIG	OVARY	80	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	0	0	0	N
RB1	SIGRLYSKE	ENDOMETRIUM	86	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	0	0	0	N
RB1	SIGRLYSKE	OVARY	86	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	0	0	0	N
RB1	SKEKGTVGN	ENDOMETRIUM	92	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	1	0	0	N
RB1	SKEKGTVGN	OVARY	92	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	1	0	0	N
RB1	SLVNLGESF	ENDOMETRIUM	73	p.R71fs	c.211_212delAG	Frame_Shift_Del	3	0.22	COLO684	N	4	0	0	N
RB1	SLVNLGESF	OVARY	73	p.R71fs	c.211_212delAG	Frame_Shift_Del	3	0.22	COLO704	N	4	0	0	N
RB1	TVGNLYLYC	ENDOMETRIUM	97	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	3	0	0	N
RB1	TVGNLYLYC	OVARY	97	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	3	0	0	N
RB1	VGNLYLYCS	ENDOMETRIUM	98	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	0	0	8	N
RB1	VGNLYLYCS	OVARY	98	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	0	0	8	N
RB1	VNLGESFIC	ENDOMETRIUM	75	p.R71fs	c.211_212delAG	Frame_Shift_Del	4	0.22	COLO684	N	0	0	6	N
RB1	VNLGESFIC	OVARY	75	p.R71fs	c.211_212delAG	Frame_Shift_Del	4	0.22	COLO704	N	0	0	6	N
RB1	VRESLVNLG	ENDOMETRIUM	70	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO684	N	1	0	6	N
RB1	VRESLVNLG	OVARY	70	p.R71fs	c.211_212delAG	Frame_Shift_Del	5	0.22	COLO704	N	1	0	6	N
RB1	WSIGRLYSK	ENDOMETRIUM	85	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	Y	5	12	2	N
RB1	WSIGRLYSK	OVARY	85	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	Y	5	12	2	N
RB1	YSKEKGTVG	ENDOMETRIUM	91	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO684	N	2	0	0	Y
RB1	YSKEKGTVG	OVARY	91	p.R71fs	c.211_212delAG	Frame_Shift_Del	6	0.22	COLO704	N	2	0	0	Y
RB1	ACALEVVMV	LUNG	488	p.A496fs	c.1486_1487insT	Frame_Shift_Ins	1	0.11	CPCN	Y	1	13	0	N
RB1	ALEVVMVHI	LUNG	490	p.A496fs	c.1486_1487insT	Frame_Shift_Ins	3	0.11	CPCN	Y	6	16	0	N
RB1	CALEVVMVH	LUNG	489	p.A496fs	c.1486_1487insT	Frame_Shift_Ins	2	0.11	CPCN	N	0	0	0	N
RB1	LTQPSSSII	LUNG	174	p.I181fs	c.541_542insT	Frame_Shift_Ins	1	0.11	NCIH596	N	6	0	0	N
RB1	SDSPLFDLN	LUNG	565	p.L572fs	c.1716_1717insA	Frame_Shift_Ins	1	0.11	DMS153	N	1	0	0	N
RB1	TQPSSSIIY	LUNG	175	p.I181fs	c.541_542insT	Frame_Shift_Ins	2	0.11	NCIH596	N	7	0	0	N
RB1	DIFHMSLLA	BREAST	479	p.N480del	c.1436_1438delACA	In_Frame_Del	1	0.11	HCC70	N	2	0	0	N
RB1	DLSFPWNVL	THYROID	511	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	3	0.11	FTC133	Y	5	11	0	N
RB1	FPWNVLNLK	THYROID	514	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	3	0.11	FTC133	N	7	0	0	Y
RB1	FSKLLNDIF	BREAST	473	p.N480del	c.1436_1438delACA	In_Frame_Del	2	0.11	HCC70	N	8	0	1	N
RB1	GTDLSFPWN	THYROID	509	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	1	0.11	FTC133	N	1	0	0	N
RB1	KLLNDIFHM	BREAST	475	p.N480del	c.1436_1438delACA	In_Frame_Del	4	0.11	HCC70	Y	9	9	0	N
RB1	LLNDIFHMS	BREAST	476	p.N480del	c.1436_1438delACA	In_Frame_Del	3	0.11	HCC70	N	0	0	6	N
RB1	LNDIFHMSL	BREAST	477	p.N480del	c.1436_1438delACA	In_Frame_Del	3	0.11	HCC70	N	10	0	1	N
RB1	LSFPWNVLN	THYROID	512	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	4	0.11	FTC133	N	0	0	0	N
RB1	NDIFHMSLL	BREAST	478	p.N480del	c.1436_1438delACA	In_Frame_Del	2	0.11	HCC70	N	7	0	0	N
RB1	NFSKLLNDI	BREAST	472	p.N480del	c.1436_1438delACA	In_Frame_Del	1	0.11	HCC70	N	5	0	0	N
RB1	PWNVLNLKA	THYROID	515	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	2	0.11	FTC133	N	0	0	0	N
RB1	SFPWNVLNL	THYROID	513	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	4	0.11	FTC133	Y	10	13	0	N
RB1	SKLLNDIFH	BREAST	474	p.N480del	c.1436_1438delACA	In_Frame_Del	3	0.11	HCC70	N	2	0	0	N
RB1	TDLSFPWNV	THYROID	510	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	2	0.11	FTC133	Y	7	10	0	N
RB1	WNVLNLKAF	THYROID	516	p.IL517del	c.1548_1553delGATTCT	In_Frame_Del	1	0.11	FTC133	Y	6	14	9	N
RB1	CIFIEAVDL	BILIARY_TRACT	102	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	8	0	0	N
RB1	CQKLKIPDN	STOMACH	61	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	N	2	0	0	N
RB1	CVEIGSLRY	LUNG	438	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	N	3	0	0	N
RB1	CVLDYFIRL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	221	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	Y	16	10	0	N
RB1	DIHLDQIMM	BONE	697	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	N	2	0	0	N
RB1	DLSFLWILN	BREAST	511	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	N	0	0	0	N
RB1	DLSFPWVLN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	511	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	N	0	0	0	N
RB1	DNVRERAWL	STOMACH	68	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	Y	7	15	0	N
RB1	DQIMMFSMY	LUNG	701	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	6	0	0	N
RB1	DREGPTEHL	LUNG	578	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	Y	5	10	0	N
RB1	DSGTDLSFL	BREAST	507	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	N	9	0	0	N
RB1	DSSIVFYNS	ENDOMETRIUM	750	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	N	1	0	0	N
RB1	DYFIRLSPP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	224	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	N	0	0	0	N
RB1	EAVDLDEMS	BILIARY_TRACT	106	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	3	0	0	N
RB1	EEEYDSSIV	ENDOMETRIUM	746	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	N	7	0	0	N
RB1	EEYDSSIVF	ENDOMETRIUM	747	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	N	9	0	0	N
RB1	EGPTEHLES	LUNG	580	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	1	0	0	N
RB1	EHLESACPL	LUNG	584	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	6	0	0	N
RB1	EHRIMESLP	LUNG	554	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	0	0	0	N
RB1	EIGSLRYKL	LUNG	440	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	Y	5	9	0	N
RB1	EIIVHKFFN	LUNG	125	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	N	0	0	0	N
RB1	EISVHKLFN	ENDOMETRIUM	125	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
RB1	ELMRDIHLD	BONE	693	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	N	0	0	0	N
RB1	ELQKNIEII	LUNG	119	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	N	7	0	0	N
RB1	ENLSKRYKE	ENDOMETRIUM	315	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	N	0	0	0	N
RB1	EPWGICIFI	KIDNEY	97	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	Y	14	13	0	N
RB1	ERTYELIYL	ENDOMETRIUM	166	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	Y	5	11	0	N
RB1	ESLPWLSDS	LUNG	559	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	1	0	0	N
RB1	EVRLYYRVM	LUNG	449	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	Y	7	9	0	N
RB1	EYDSSIVFY	ENDOMETRIUM	748	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	Y	4	13	0	N
RB1	EYELMRDIH	BONE	691	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	N	1	0	0	N
RB1	FHMSLLVCA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	482	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	N	5	0	16	N
RB1	FIEAVDLDE	BILIARY_TRACT	104	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	2	0	0	N
RB1	FIRLSPPML	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	226	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	N	10	0	15	N
RB1	FLWILNVLN	BREAST	514	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	N	4	0	6	N
RB1	FPSSPLQIP	LARGE_INTESTINE	792	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	N	3	0	0	N
RB1	FPWVLNVLN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	514	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	N	7	0	0	N
RB1	FQKINQMLC	CENTRAL_NERVOUS_SYSTEM	845	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	Y	5	13	12	N
RB1	FSKLERTYE	ENDOMETRIUM	162	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	N	2	0	0	N
RB1	FSKLPNDNI	AUTONOMIC_GANGLIA	473	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	9	0	0	N
RB1	FSMYGICKV	LUNG	706	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	10	0	11	N
RB1	FYKKMYRLA	PLEURA	650	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	N	5	0	3	N
RB1	GCVEIGSLR	LUNG	437	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	N	5	0	0	N
RB1	GGYIQNKKE	ENDOMETRIUM	89	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
RB1	GICIFIEAV	BILIARY_TRACT	100	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	Y	4	9	0	N
RB1	GKSFGTSEK	LUNG	836	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	1	0	0	Y
RB1	GPTEHLESA	LUNG	581	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	10	0	0	N
RB1	GSLRYKLGV	LUNG	442	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	N	5	0	0	N
RB1	GSQRYKLEV	LUNG	442	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	N	4	0	0	N
RB1	GTDLSFLWI	BREAST	509	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	Y	5	12	0	N
RB1	GTDLSFPWV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	509	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	Y	6	10	0	N
RB1	GVLGGYIQN	ENDOMETRIUM	86	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
RB1	GYIQKKKEP	KIDNEY	90	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	N	0	0	0	N
RB1	GYIQNKKEL	ENDOMETRIUM	90	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	Y	8	9	0	N
RB1	HKLFNLLKE	ENDOMETRIUM	129	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
RB1	HLDQIMMFS	LUNG	699	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	1	0	0	N
RB1	HMSLLVCAL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	483	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	Y	11	9	0	N
RB1	HRIMESLPW	LUNG	555	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	3	0	0	N
RB1	ICIFIEAVD	BILIARY_TRACT	101	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	0	0	0	N
RB1	IEAVDLDEM	BILIARY_TRACT	105	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	7	0	0	N
RB1	IEIIVHKFF	LUNG	124	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	N	10	0	2	N
RB1	IEISVHKLF	ENDOMETRIUM	124	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	N	9	0	0	N
RB1	IFHMSLLVC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	481	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	N	1	0	21	N
RB1	IFIEAVDLD	BILIARY_TRACT	103	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	0	0	3	N
RB1	IGKSFGTSE	LUNG	835	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	0	0	0	N
RB1	IGSLRYKLG	LUNG	441	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	N	0	0	0	N
RB1	IGSQRYKLE	LUNG	441	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	N	0	0	0	N
RB1	IHLDQIMMC	BONE	698	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	N	2	0	16	N
RB1	IIVHKFFNL	LUNG	126	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	Y	15	9	5	N
RB1	IKEEEYDSS	ENDOMETRIUM	744	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	N	1	0	0	N
RB1	ILVSIGKSF	LUNG	831	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	6	0	1	N
RB1	IMESLPWLS	LUNG	557	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	1	0	0	N
RB1	IMMFSMYGI	LUNG	703	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	13	0	16	N
RB1	INQMLCNSD	CENTRAL_NERVOUS_SYSTEM	848	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	N	0	0	3	N
RB1	IPDNVRERA	STOMACH	66	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	N	8	0	0	N
RB1	IQKKKEPWG	KIDNEY	92	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	N	0	0	0	N
RB1	IQNFSKLPN	AUTONOMIC_GANGLIA	470	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	26	N
RB1	IQNKKELWG	ENDOMETRIUM	92	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	N	0	0	2	N
RB1	IQQLMMSLN	BREAST	382	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	0	0	0	N
RB1	IRLSPPMLL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	227	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	Y	11	9	43	N
RB1	ISVHKLFNL	ENDOMETRIUM	126	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	Y	19	10	2	N
RB1	IVHKFFNLL	LUNG	127	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	Y	16	9	2	N
RB1	KDREGPTEH	LUNG	577	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	0	0	0	N
RB1	KEEEYDSSI	ENDOMETRIUM	745	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	Y	9	11	0	N
RB1	KEIYLKNKD	ENDOMETRIUM	322	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	N	2	0	0	N
RB1	KEPWGICIF	KIDNEY	96	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	Y	13	9	0	N
RB1	KFPSSPLQI	LARGE_INTESTINE	791	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	N	5	0	0	N
RB1	KFQKINQML	CENTRAL_NERVOUS_SYSTEM	844	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	Y	10	9	0	N
RB1	KINQMLCNS	CENTRAL_NERVOUS_SYSTEM	847	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	N	0	0	0	N
RB1	KIPDNVRER	STOMACH	65	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	Y	4	9	0	Y
RB1	KKEPWGICI	KIDNEY	95	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	N	4	0	0	N
RB1	KKKEPWGIC	KIDNEY	94	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	N	1	0	0	N
RB1	KKMYRLAYL	PLEURA	652	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	Y	10	12	0	N
RB1	KLERTYELI	ENDOMETRIUM	164	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	N	6	0	0	N
RB1	KLEVRLYYR	LUNG	447	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	Y	8	11	0	N
RB1	KLFNLLKEI	ENDOMETRIUM	130	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	N	15	0	0	N
RB1	KLKIPDNVR	STOMACH	63	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	N	7	0	0	N
RB1	KLPNDNIFH	AUTONOMIC_GANGLIA	475	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	1	0	0	N
RB1	KMYRLAYLR	PLEURA	653	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	Y	9	10	0	N
RB1	KNIEIIVHK	LUNG	122	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	N	3	0	0	N
RB1	KRYKEIYLK	ENDOMETRIUM	319	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	Y	4	10	0	N
RB1	KSFGTSEKF	LUNG	837	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	9	0	0	N
RB1	LCNSDRVLK	CENTRAL_NERVOUS_SYSTEM	852	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	N	1	0	1	N
RB1	LCVLDYFIR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	220	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	N	5	0	2	N
RB1	LDQIMMFSM	LUNG	700	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	5	0	0	N
RB1	LDYFIRLSP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	223	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	N	0	0	2	N
RB1	LERTYELIY	ENDOMETRIUM	165	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	N	8	0	0	N
RB1	LEVRLYYRV	LUNG	448	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	N	11	0	0	N
RB1	LFNLLKEID	ENDOMETRIUM	131	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	2	N
RB1	LFSKLERTY	ENDOMETRIUM	161	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	N	3	0	0	N
RB1	LFYKKMYRL	PLEURA	649	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	N	14	0	0	N
RB1	LGGYIQNKK	ENDOMETRIUM	88	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	N	0	0	1	N
RB1	LKIPDNVRE	STOMACH	64	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	N	0	0	2	N
RB1	LLVCALEVV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	486	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	N	9	0	0	N
RB1	LMMSLNSAS	BREAST	385	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	0	0	17	N
RB1	LMRDIHLDQ	BONE	694	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	N	0	0	13	N
RB1	LPNDNIFHM	AUTONOMIC_GANGLIA	476	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	Y	12	9	4	N
RB1	LPWLSDSPL	LUNG	561	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	19	0	0	N
RB1	LQIPGGNIY	LARGE_INTESTINE	797	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	Y	9	15	0	N
RB1	LQKNIEIIV	LUNG	120	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	N	6	0	0	N
RB1	LRYKLGVRL	LUNG	444	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	Y	11	10	19	Y
RB1	LSFLWILNV	BREAST	512	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	N	13	0	9	N
RB1	LSFPWVLNV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	512	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	N	12	0	0	N
RB1	LSKRYKEIY	ENDOMETRIUM	317	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	N	7	0	0	N
RB1	LSLFYKKMY	PLEURA	647	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	N	8	0	9	N
RB1	LVCALEVVM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	487	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	N	7	0	0	N
RB1	LVSIGKSFG	LUNG	832	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	0	0	20	N
RB1	LWGICIFIE	BILIARY_TRACT	98	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	0	0	0	N
RB1	LWILNVLNL	BREAST	515	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	N	10	0	42	N
RB1	MESLPWLSD	LUNG	558	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	0	0	0	N
RB1	MFSMYGICK	LUNG	705	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	1	0	2	N
RB1	MLCNSDRVL	CENTRAL_NERVOUS_SYSTEM	851	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	Y	5	10	0	N
RB1	MMFSMYGIC	LUNG	704	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	6	0	0	N
RB1	MMSLNSASD	BREAST	386	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	2	0	6	N
RB1	MRDIHLDQI	BONE	695	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	N	5	0	0	N
RB1	MSLLVCALE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	484	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	N	0	0	3	N
RB1	MSLNSASDQ	BREAST	387	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	0	0	0	N
RB1	MYRLAYLRL	PLEURA	654	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	Y	9	10	7	N
RB1	NEYELMRDI	BONE	690	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	Y	11	9	0	N
RB1	NFSKLPNDN	AUTONOMIC_GANGLIA	472	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	0	N
RB1	NIEIIVHKF	LUNG	123	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	N	5	0	0	N
RB1	NIEISVHKL	ENDOMETRIUM	123	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	N	7	0	0	N
RB1	NIFHMSLLV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	480	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	Y	7	9	0	N
RB1	NKKELWGIC	ENDOMETRIUM	94	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	N	1	0	0	N
RB1	NLSKRYKEI	ENDOMETRIUM	316	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	Y	9	10	0	N
RB1	NQMLCNSDR	CENTRAL_NERVOUS_SYSTEM	849	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	N	6	0	0	N
RB1	NTIQQLMMS	BREAST	380	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	0	0	0	N
RB1	NVRERAWLT	STOMACH	69	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	N	2	0	0	N
RB1	PDNVRERAW	STOMACH	67	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	N	0	0	0	N
RB1	PLQIPGGNI	LARGE_INTESTINE	796	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	N	1	0	0	N
RB1	PNDNIFHMS	AUTONOMIC_GANGLIA	477	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	0	N
RB1	PSSPLQIPG	LARGE_INTESTINE	793	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	N	0	0	0	N
RB1	PTEHLESAC	LUNG	582	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	0	0	0	N
RB1	PWGICIFIA	KIDNEY	98	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	N	0	0	0	N
RB1	PWLSDSPLF	LUNG	562	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	0	0	0	N
RB1	PWVLNVLNL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	515	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	Y	3	13	0	N
RB1	QGCVEIGSL	LUNG	436	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	N	8	0	0	N
RB1	QIMMFSMYG	LUNG	702	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	N	0	0	0	N
RB1	QIPGGNIYI	LARGE_INTESTINE	798	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	Y	4	10	0	N
RB1	QKINQMLCN	CENTRAL_NERVOUS_SYSTEM	846	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	N	1	0	0	N
RB1	QKKKEPWGI	KIDNEY	93	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	N	1	0	0	N
RB1	QKLKIPDNV	STOMACH	62	p.H69N	c.205C>A	Missense_Mutation	1	0.11	GSU	N	2	0	0	N
RB1	QKNIEIIVH	LUNG	121	p.S127I	c.380G>T	Missense_Mutation	1	0.11	NCIH1734	N	1	0	0	N
RB1	QLMMSLNSA	BREAST	384	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	5	0	0	N
RB1	QMLCNSDRV	CENTRAL_NERVOUS_SYSTEM	850	p.V852L	c.2554G>C	Missense_Mutation	1	0.11	A172	Y	8	11	0	N
RB1	QNFSKLPND	AUTONOMIC_GANGLIA	471	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	0	N
RB1	QNKKELWGI	ENDOMETRIUM	93	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	N	1	0	0	N
RB1	QQLMMSLNS	BREAST	383	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	0	0	0	N
RB1	QRYKLEVRL	LUNG	444	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	Y	9	12	0	N
RB1	RDIHLDQIM	BONE	696	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	N	7	0	0	N
RB1	REGPTEHLE	LUNG	579	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	0	0	0	N
RB1	RHLDQIMMF	LUNG	698	p.C706F	c.2117G>T	Missense_Mutation	1	0.11	NCIH209	Y	5	9	0	N
RB1	RILVSIGKS	LUNG	830	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	0	0	0	N
RB1	RIMESLPWL	LUNG	556	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	Y	16	10	0	N
RB1	RLSPPMLLK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	228	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	Y	6	15	0	N
RB1	RTYELIYLT	ENDOMETRIUM	167	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	N	3	0	0	N
RB1	RYKEIYLKN	ENDOMETRIUM	320	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	N	2	0	0	N
RB1	RYKLEVRLY	LUNG	445	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	N	4	0	0	N
RB1	SFLWILNVL	BREAST	513	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	Y	11	9	0	N
RB1	SFPWVLNVL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	513	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	Y	11	9	0	N
RB1	SGTDLSFLW	BREAST	508	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	N	2	0	0	N
RB1	SIGKSFGTS	LUNG	834	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	1	0	0	N
RB1	SIQNFSKLP	AUTONOMIC_GANGLIA	469	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	0	N
RB1	SIVFYNSVF	ENDOMETRIUM	752	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	N	3	0	0	N
RB1	SKDREGPTE	LUNG	576	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	0	0	0	N
RB1	SKLERTYEL	ENDOMETRIUM	163	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	Y	8	11	0	N
RB1	SKLPNDNIF	AUTONOMIC_GANGLIA	474	p.L477P	c.1430T>C	Missense_Mutation	1	0.11	SKNAS	N	5	0	0	N
RB1	SKRYKEIYL	ENDOMETRIUM	318	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	Y	6	9	0	N
RB1	SLFYKKMYR	PLEURA	648	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	Y	7	9	0	N
RB1	SLLVCALEV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	485	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	Y	7	10	0	N
RB1	SLNSASDQP	BREAST	388	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	N	0	0	0	N
RB1	SLPWLSDSP	LUNG	560	p.A562P	c.1684G>C	Missense_Mutation	1	0.11	NCIH2172	N	0	0	0	N
RB1	SLRYKLGVR	LUNG	443	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	Y	6	9	0	Y
RB1	SLSLFYKKM	PLEURA	646	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	Y	7	9	0	N
RB1	SPLQIPGGN	LARGE_INTESTINE	795	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	N	4	0	0	N
RB1	SQRYKLEVR	LUNG	443	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	N	5	0	0	N
RB1	SRILVSIGK	LUNG	829	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	2	0	0	N
RB1	SSIVFYNSV	ENDOMETRIUM	751	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	Y	7	10	0	N
RB1	SSPLQIPGG	LARGE_INTESTINE	794	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	N	0	0	0	N
RB1	SVHKLFNLL	ENDOMETRIUM	127	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	Y	13	10	0	N
RB1	TDLSFLWIL	BREAST	510	p.P515L	c.1544C>T	Missense_Mutation	1	0.11	BT20	Y	13	10	0	N
RB1	TDLSFPWVL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	510	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	N	10	0	0	N
RB1	TEHLESACP	LUNG	583	p.D584E	c.1752T>G	Missense_Mutation	1	0.11	CORL24	N	0	0	0	N
RB1	TIQQLMMSL	BREAST	381	p.I388S	c.1163T>G	Missense_Mutation	1	0.11	BT20	Y	9	9	0	N
RB1	TYELIYLTQ	ENDOMETRIUM	168	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
RB1	VCALEVVMA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	488	p.A488V	c.1463C>T	Missense_Mutation	1	0.11	P31FUJ	N	2	0	2	N
RB1	VEIGSLRYK	LUNG	439	p.Q444L	c.1331A>T	Missense_Mutation	1	0.11	NCIH1694	Y	2	14	0	N
RB1	VENLSKRYK	ENDOMETRIUM	314	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	N	0	0	18	N
RB1	VHKLFNLLK	ENDOMETRIUM	128	p.F131L	c.393C>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	13	N
RB1	VLDYFIRLS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	222	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	N	1	0	14	N
RB1	VLGGYIQNK	ENDOMETRIUM	87	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	Y	7	17	4	N
RB1	VLNVLNLKA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	517	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	N	5	0	15	N
RB1	VSIGKSFGT	LUNG	833	p.E837K	c.2509G>A	Missense_Mutation	1	0.11	CHAGOK1	N	2	0	0	N
RB1	WGICIFIEA	BILIARY_TRACT	99	p.A106E	c.317C>A	Missense_Mutation	1	0.11	HUCCT1	N	4	0	2	N
RB1	WVLNVLNLK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	516	p.I517V	c.1549A>G	Missense_Mutation	1	0.11	HT	Y	6	15	24	N
RB1	YDSSIVFYN	ENDOMETRIUM	749	p.I752S	c.2255T>G	Missense_Mutation	1	0.11	HEC251	N	4	0	0	N
RB1	YELIYLTQP	ENDOMETRIUM	169	p.C169Y	c.506G>A	Missense_Mutation	1	0.11	HEC108	N	3	0	0	N
RB1	YELMRDIHL	BONE	692	p.R698I	c.2093_2094GG>TT	Missense_Mutation	1	0.11	SKNMC	Y	15	9	5	N
RB1	YFIRLSPPM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	225	p.K228R	c.683A>G	Missense_Mutation	1	0.11	U266B1	N	6	0	15	N
RB1	YIQKKKEPW	KIDNEY	91	p.L98P	c.293T>C	Missense_Mutation	1	0.11	CAKI1	N	5	0	4	N
RB1	YIQNKKELW	ENDOMETRIUM	91	p.K94N	c.282G>T	Missense_Mutation	1	0.11	HEC251	N	3	0	0	N
RB1	YKEIYLKNK	ENDOMETRIUM	321	p.E322K	c.964G>A	Missense_Mutation	1	0.11	ESS1	N	4	0	2	N
RB1	YKFPSSPLQ	LARGE_INTESTINE	790	p.R798Q	c.2393G>A	Missense_Mutation	1	0.11	SNU175	N	2	0	1	N
RB1	YKKMYRLAY	PLEURA	651	p.V654M	c.1960G>A	Missense_Mutation	1	0.11	MPP89	N	6	0	24	N
RB1	YKLEVRLYY	LUNG	446	p.G449E	c.1346G>A	Missense_Mutation	1	0.11	NCIH2110	Y	6	14	12	N
RB1	GSTTSVNST	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	617	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	1	0	0	N
RB1	GSTTSVNST	OVARY	617	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	1	0	0	N
RB1	GSTTSVNST	STOMACH	617	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	1	0	0	N
RB1	KGSTTSVNS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	616	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	1	0	0	N
RB1	KGSTTSVNS	OVARY	616	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	1	0	0	N
RB1	KGSTTSVNS	STOMACH	616	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	1	0	0	N
RB1	KKGSTTSVN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	615	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	1	0	0	N
RB1	KKGSTTSVN	OVARY	615	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	1	0	0	N
RB1	KKGSTTSVN	STOMACH	615	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	1	0	0	N
RB1	KKKGSTTSV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	614	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	2	0	0	N
RB1	KKKGSTTSV	OVARY	614	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	2	0	0	N
RB1	KKKGSTTSV	STOMACH	614	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	2	0	0	N
RB1	PKKKGSTTS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	613	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	0	0	0	N
RB1	PKKKGSTTS	OVARY	613	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	0	0	0	N
RB1	PKKKGSTTS	STOMACH	613	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	0	0	0	N
RB1	STTSVNSTA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	618	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	1	0	0	N
RB1	STTSVNSTA	OVARY	618	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	1	0	0	N
RB1	STTSVNSTA	STOMACH	618	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	1	0	0	N
RB1	SVNSTANAE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	621	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	0	0	0	N
RB1	SVNSTANAE	OVARY	621	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	0	0	0	N
RB1	SVNSTANAE	STOMACH	621	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	0	0	0	N
RB1	TSVNSTANA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	620	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	3	0	0	N
RB1	TSVNSTANA	OVARY	620	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	3	0	0	N
RB1	TSVNSTANA	STOMACH	620	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	3	0	0	N
RB1	TTSVNSTAN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	619	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JEKO1	N	0	0	0	N
RB1	TTSVNSTAN	OVARY	619	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	JHOM1	N	0	0	0	N
RB1	TTSVNSTAN	STOMACH	619	p.R621S	c.1861C>A	Missense_Mutation	1	0.33	SNU719	N	0	0	0	N