Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
FLT3	DLGLLSAGS	LARGE_INTESTINE	980	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	3	0.33	GP2D	N	0	0	0	N
FLT3	DLGLLSAGS	LARGE_INTESTINE	980	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	3	0.33	HCT116	N	0	0	0	N
FLT3	DLGLLSAGS	LARGE_INTESTINE	980	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	3	0.33	LS411N	N	0	0	0	N
FLT3	EMDLGLLSA	LARGE_INTESTINE	978	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	1	0.33	GP2D	N	2	0	0	N
FLT3	EMDLGLLSA	LARGE_INTESTINE	978	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	1	0.33	HCT116	N	2	0	0	N
FLT3	EMDLGLLSA	LARGE_INTESTINE	978	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	1	0.33	LS411N	N	2	0	0	N
FLT3	GLLSAGSGR	LARGE_INTESTINE	982	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	5	0.33	GP2D	N	6	0	0	N
FLT3	GLLSAGSGR	LARGE_INTESTINE	982	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	5	0.33	HCT116	N	6	0	0	N
FLT3	GLLSAGSGR	LARGE_INTESTINE	982	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	5	0.33	LS411N	N	6	0	0	N
FLT3	LGLLSAGSG	LARGE_INTESTINE	981	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	4	0.33	GP2D	N	0	0	0	N
FLT3	LGLLSAGSG	LARGE_INTESTINE	981	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	4	0.33	HCT116	N	0	0	0	N
FLT3	LGLLSAGSG	LARGE_INTESTINE	981	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	4	0.33	LS411N	N	0	0	0	N
FLT3	LLSAGSGRR	LARGE_INTESTINE	983	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	6	0.33	GP2D	N	5	0	2	N
FLT3	LLSAGSGRR	LARGE_INTESTINE	983	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	6	0.33	HCT116	N	5	0	2	N
FLT3	LLSAGSGRR	LARGE_INTESTINE	983	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	6	0.33	LS411N	N	5	0	2	N
FLT3	LSAGSGRRF	LARGE_INTESTINE	984	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	6	0.33	GP2D	N	6	0	0	N
FLT3	LSAGSGRRF	LARGE_INTESTINE	984	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	6	0.33	HCT116	N	6	0	0	N
FLT3	LSAGSGRRF	LARGE_INTESTINE	984	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	6	0.33	LS411N	N	6	0	0	N
FLT3	MDLGLLSAG	LARGE_INTESTINE	979	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	2	0.33	GP2D	N	0	0	0	N
FLT3	MDLGLLSAG	LARGE_INTESTINE	979	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	2	0.33	HCT116	N	0	0	0	N
FLT3	MDLGLLSAG	LARGE_INTESTINE	979	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	2	0.33	LS411N	N	0	0	0	N
FLT3	SAGSGRRFV	LARGE_INTESTINE	985	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	5	0.33	GP2D	Y	3	9	0	N
FLT3	SAGSGRRFV	LARGE_INTESTINE	985	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	5	0.33	HCT116	Y	3	9	0	N
FLT3	SAGSGRRFV	LARGE_INTESTINE	985	p.S985fs	c.2955_2956delTC	Frame_Shift_Del	5	0.33	LS411N	Y	3	9	0	N
FLT3	AARNVLATH	ENDOMETRIUM	813	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	Y	0	11	0	N
FLT3	AARNVLVNH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	813	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	Y	0	15	0	N
FLT3	AAVEVDVSP	LUNG	79	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	N	0	0	0	N
FLT3	ACLPVKWMA	ENDOMETRIUM	848	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	1	0	0	N
FLT3	ACPQIRCTW	PROSTATE	375	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
FLT3	ACQASCFSD	LUNG	447	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	0	0	0	N
FLT3	ADAEEVMYQ	ENDOMETRIUM	948	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	0	0	0	N
FLT3	AEASACQAS	LUNG	443	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	4	0	0	N
FLT3	AEEVMYQNV	ENDOMETRIUM	950	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	6	0	0	N
FLT3	AFVSSVARK	LUNG	315	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	Y	2	13	0	N
FLT3	ALMSVLKMM	LUNG	657	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	Y	8	10	0	N
FLT3	ALRPQCSGT	LUNG	66	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	1	0	0	N
FLT3	AMYQNVDGS	LUNG	953	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	4	0	0	N
FLT3	ARKDTGYYT	LUNG	321	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	Y	2	10	0	N
FLT3	ARNVLATHG	ENDOMETRIUM	814	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
FLT3	ARNVLVNHG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	814	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	Y	1	9	0	N
FLT3	ASACQASCF	LUNG	445	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	Y	4	10	0	N
FLT3	ATAYGISNT	SKIN	627	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	1	0	0	N
FLT3	ATHGKVVKI	ENDOMETRIUM	819	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	Y	6	17	0	N
FLT3	AVEVDVSPS	LUNG	80	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	N	1	0	0	N
FLT3	AYGISNTGV	SKIN	629	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	Y	2	11	0	N
FLT3	CALRPQCSG	LUNG	65	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	0	0	0	N
FLT3	CFSVRFKAC	PROSTATE	368	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
FLT3	CLPVKWMAP	ENDOMETRIUM	849	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
FLT3	CPQIRCTWT	PROSTATE	376	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	5	0	0	N
FLT3	CQASCFSDG	LUNG	448	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	0	0	0	N
FLT3	CQLADAEEV	ENDOMETRIUM	945	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	8	0	0	Y
FLT3	CQLTDAEEA	LARGE_INTESTINE	945	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	3	0	0	N
FLT3	CQSHFDLQN	LARGE_INTESTINE	114	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
FLT3	CSGTVYEAA	LUNG	71	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	2	0	0	N
FLT3	DAEEVMYQN	ENDOMETRIUM	949	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	3	0	0	N
FLT3	DGSVSECPH	LUNG	959	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	0	0	0	N
FLT3	DLAARNVLA	ENDOMETRIUM	811	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	N	2	0	0	N
FLT3	DNGYSIFKF	SKIN	398	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	4	0	0	N
FLT3	DQISGLHEN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	750	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	0	0	0	N
FLT3	DQPFYTTEE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	909	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	0	0	0	N
FLT3	DSRKRPSFH	LUNG	929	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	N	2	0	0	N
FLT3	DVSPSITLQ	LUNG	84	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	N	1	0	0	N
FLT3	EALMSVLKM	LUNG	656	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	N	7	0	0	N
FLT3	EASACQASC	LUNG	444	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	2	0	0	N
FLT3	EEVMYQNVD	ENDOMETRIUM	951	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	1	0	0	N
FLT3	EFKSGVHRD	LUNG	803	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	0	0	0	N
FLT3	EFLEFKSGV	LUNG	800	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	3	0	0	N
FLT3	EGVWNTKAN	LUNG	480	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	1	0	0	N
FLT3	EITEGVWNT	LUNG	477	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	2	0	0	N
FLT3	ENIVNLLGV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	672	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	3	0	0	N
FLT3	ENSFHSEDE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	757	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	0	0	0	N
FLT3	EREALMSVL	LUNG	654	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	Y	8	11	0	N
FLT3	ETFHRTWTE	LARGE_INTESTINE	708	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	N	0	0	0	N
FLT3	EVDVSPSIT	LUNG	82	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	N	2	0	0	N
FLT3	EVMYQNVDG	ENDOMETRIUM	952	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	0	0	0	N
FLT3	FHNLTSFLG	LUNG	936	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	N	2	0	12	N
FLT3	FKACPQIRC	PROSTATE	373	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	3	0	1	N
FLT3	FKFCNHKHQ	SKIN	404	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	2	0	10	N
FLT3	FKMDQPFYT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	906	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	4	0	11	N
FLT3	FKSGVHRDL	LUNG	804	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	6	0	0	N
FLT3	FLEFKSGVH	LUNG	801	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	3	0	0	N
FLT3	FLGCQLTDA	LARGE_INTESTINE	942	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	7	0	0	N
FLT3	FQSHPNSSV	LARGE_INTESTINE	729	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	11	0	6	N
FLT3	FRRPYFRKM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	168	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	Y	6	9	2	N
FLT3	FSVRFKACP	PROSTATE	369	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	2	0	4	N
FLT3	FVSSVARKD	LUNG	316	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	N	2	0	4	N
FLT3	FYTTEEIYI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	912	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	9	0	2	N
FLT3	GCALRPQCS	LUNG	64	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	0	0	0	N
FLT3	GCQLTDAEE	LARGE_INTESTINE	944	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
FLT3	GISNTGVSI	SKIN	631	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	1	0	0	N
FLT3	GLDNGYSIF	SKIN	396	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	6	0	0	N
FLT3	GLHENSFHS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	754	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	1	0	0	N
FLT3	GNACLPVKW	ENDOMETRIUM	846	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	2	0	0	N
FLT3	GSVSECPHT	LUNG	960	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	1	0	0	N
FLT3	GVCTLSGPI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	679	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	3	0	0	N
FLT3	GVHRDLAAR	LUNG	807	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	Y	6	10	0	N
FLT3	GVWNTKANR	LUNG	481	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	7	0	0	N
FLT3	GYSIFKFCN	SKIN	400	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	0	0	0	N
FLT3	HENSFHSED	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	756	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	0	0	0	N
FLT3	HGSREVQIH	LUNG	738	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	0	0	0	N
FLT3	HNLTSFLGC	LUNG	937	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	N	0	0	0	N
FLT3	HPNSSMHGS	LUNG	732	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	4	0	0	N
FLT3	HPNSSMPRS	AUTONOMIC_GANGLIA	732	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	5	0	0	N
FLT3	HPNSSMRGS	BONE	732	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	N	4	0	0	N
FLT3	HPNSSVPGS	LARGE_INTESTINE	732	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	4	0	0	N
FLT3	HSSLNCQSH	LARGE_INTESTINE	109	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	1	0	0	N
FLT3	IFKFCNHKH	SKIN	403	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	0	0	9	N
FLT3	IRNTLLYTF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	160	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	N	5	0	4	N
FLT3	IRRKPQVPA	ENDOMETRIUM	435	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	5	0	17	N
FLT3	ISGLHENSF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	752	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	4	0	0	N
FLT3	ISNTGVSIQ	SKIN	632	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	0	0	0	N
FLT3	ITEGVWNTK	LUNG	478	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	Y	3	20	0	N
FLT3	IVNLLGVCT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	674	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	1	0	4	N
FLT3	IWILFAFVS	ENDOMETRIUM	310	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	N	0	0	31	N
FLT3	KACPQIRCT	PROSTATE	374	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	2	0	0	N
FLT3	KDTGYYTCS	LUNG	323	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	N	2	0	0	N
FLT3	KHSSLNCQS	LARGE_INTESTINE	108	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	1	0	0	N
FLT3	KMDQPFYTT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	907	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	4	0	0	N
FLT3	KPQVPAEAS	ENDOMETRIUM	438	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	3	0	0	N
FLT3	KRETFHRTW	LARGE_INTESTINE	706	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	N	4	0	0	N
FLT3	KRPSFHNLT	LUNG	932	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	N	3	0	0	N
FLT3	KSGVHRDLA	LUNG	805	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	2	0	0	N
FLT3	LAARNVLAT	ENDOMETRIUM	812	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	N	5	0	5	N
FLT3	LAARNVLVN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	812	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	N	2	0	4	N
FLT3	LADAEEVMY	ENDOMETRIUM	947	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	6	0	0	N
FLT3	LAEASACQA	LUNG	442	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	4	0	0	N
FLT3	LATHGKVVK	ENDOMETRIUM	818	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	N	1	0	5	N
FLT3	LDNGYSIFK	SKIN	397	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	1	0	0	N
FLT3	LEFKSGVHR	LUNG	802	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	3	0	0	N
FLT3	LGCALRPQC	LUNG	63	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	0	0	1	N
FLT3	LGCQLTDAE	LARGE_INTESTINE	943	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
FLT3	LGVCTLSGP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	678	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	0	0	0	N
FLT3	LHENSFHSE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	755	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	0	0	0	N
FLT3	LLGVCTLSG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	677	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	0	0	15	N
FLT3	LLYTFRRPY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	164	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	N	11	0	11	N
FLT3	LMSVLKMMT	LUNG	658	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	N	2	0	14	N
FLT3	LNCQSHFDL	LARGE_INTESTINE	112	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	5	0	0	N
FLT3	LRPQCSGTV	LUNG	67	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	5	0	3	N
FLT3	LRSKRETFH	LARGE_INTESTINE	703	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	N	2	0	1	N
FLT3	LTDAEEAMY	LARGE_INTESTINE	947	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	4	0	0	N
FLT3	LVNHGKVVK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	818	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	Y	3	16	24	N
FLT3	LYTFRRPYF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	165	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	Y	5	9	8	N
FLT3	MDQPFYTTE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	908	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	0	0	0	N
FLT3	MEFLEFKSG	LUNG	799	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	2	0	0	N
FLT3	MHGSREVQI	LUNG	737	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	5	0	1	N
FLT3	MIWILFAFV	ENDOMETRIUM	309	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	Y	10	10	0	N
FLT3	MPRSREVQI	AUTONOMIC_GANGLIA	737	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	13	0	0	N
FLT3	MRGSREVQI	BONE	737	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	N	5	0	3	N
FLT3	MSVLKMMTQ	LUNG	659	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	N	0	0	4	N
FLT3	MYQNVDGSV	LUNG	954	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	5	0	0	N
FLT3	NACLPVKWM	ENDOMETRIUM	847	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	7	0	0	N
FLT3	NATAYGISN	SKIN	626	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	1	0	0	N
FLT3	NCQSHFDLQ	LARGE_INTESTINE	113	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
FLT3	NGYSIFKFC	SKIN	399	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	4	0	0	N
FLT3	NHGKVVKIC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	820	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	N	1	0	0	N
FLT3	NIRRKPQVP	ENDOMETRIUM	434	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	1	0	0	N
FLT3	NIVNLLGVC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	673	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	0	0	0	N
FLT3	NLLGVCTLS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	676	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	0	0	0	Y
FLT3	NRTMIWILF	ENDOMETRIUM	306	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	N	4	0	0	N
FLT3	NSSMHGSRE	LUNG	734	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	0	0	0	N
FLT3	NSSMPRSRE	AUTONOMIC_GANGLIA	734	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	0	N
FLT3	NSSMRGSRE	BONE	734	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	N	0	0	0	N
FLT3	NSSVPGSRE	LARGE_INTESTINE	734	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	0	0	0	N
FLT3	NTGVSIQVA	SKIN	634	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	1	0	0	N
FLT3	NTKANRKVF	LUNG	484	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	5	0	0	N
FLT3	NTLLYTFRR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	162	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	N	7	0	0	N
FLT3	NVDGSVSEC	LUNG	957	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	0	0	0	N
FLT3	NVLATHGKV	ENDOMETRIUM	816	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	Y	3	10	0	N
FLT3	NVLVNHGKV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	816	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	Y	5	11	0	N
FLT3	NYLRSKRET	LARGE_INTESTINE	701	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	N	3	0	0	N
FLT3	NYVVRGNAC	ENDOMETRIUM	841	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	3	0	0	N
FLT3	PAEASASQA	ENDOMETRIUM	442	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	0	0	0	N
FLT3	PFYTTEEIY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	911	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	0	0	0	N
FLT3	PNSSMHGSR	LUNG	733	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	0	0	0	N
FLT3	PNSSMPRSR	AUTONOMIC_GANGLIA	733	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	0	N
FLT3	PNSSMRGSR	BONE	733	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	N	0	0	0	N
FLT3	PNSSVPGSR	LARGE_INTESTINE	733	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	0	0	0	N
FLT3	PQCSGTVYE	LUNG	69	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	0	0	0	N
FLT3	PQVPAEASA	ENDOMETRIUM	439	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	1	0	0	N
FLT3	PRSREVQIH	AUTONOMIC_GANGLIA	738	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	1	0	0	N
FLT3	PSFHNLTSF	LUNG	934	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	N	2	0	0	N
FLT3	PSITLQVLV	LUNG	87	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	N	1	0	0	N
FLT3	QCSGTVYEA	LUNG	70	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	0	0	0	N
FLT3	QISGLHENS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	751	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	0	0	0	N
FLT3	QLADAEEVM	ENDOMETRIUM	946	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	3	0	0	N
FLT3	QLTDAEEAM	LARGE_INTESTINE	946	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	3	0	0	N
FLT3	QNVDGSVSE	LUNG	956	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	0	0	0	N
FLT3	QPFYTTEEI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	910	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	13	0	0	N
FLT3	QSHFDLQNR	LARGE_INTESTINE	115	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	Y	3	10	0	N
FLT3	QSHPNSSMH	LUNG	730	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	1	0	0	N
FLT3	QSHPNSSMR	BONE	730	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	Y	5	12	0	N
FLT3	QSHPNSSVP	LARGE_INTESTINE	730	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	1	0	0	N
FLT3	QVLAEASAC	LUNG	440	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	1	0	0	N
FLT3	QVPAEASAS	ENDOMETRIUM	440	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	0	0	0	N
FLT3	REALMSVLK	LUNG	655	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	N	2	0	0	N
FLT3	RETFHRTWT	LARGE_INTESTINE	707	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	N	5	0	0	N
FLT3	RFKACPQIR	PROSTATE	372	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
FLT3	RGNACLPVK	ENDOMETRIUM	845	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
FLT3	RGSREVQIH	BONE	738	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	N	0	0	0	N
FLT3	RKDTGYYTC	LUNG	322	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	N	1	0	0	N
FLT3	RKPQVPAEA	ENDOMETRIUM	437	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	2	0	0	N
FLT3	RKRPSFHNL	LUNG	931	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	Y	5	14	0	N
FLT3	RNTLLYTFR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	161	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	N	2	0	0	N
FLT3	RNVLATHGK	ENDOMETRIUM	815	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	N	2	0	0	N
FLT3	RNVLVNHGK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	815	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	N	2	0	0	N
FLT3	RPQCSGTVY	LUNG	68	p.S71C	c.211A>T	Missense_Mutation	1	0.11	HCC1438	N	12	0	0	N
FLT3	RPSFHNLTS	LUNG	933	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	N	3	0	0	N
FLT3	RRKPQVPAE	ENDOMETRIUM	436	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	3	0	0	N
FLT3	RSKRETFHR	LARGE_INTESTINE	704	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	Y	3	11	0	N
FLT3	RSREVQIHP	AUTONOMIC_GANGLIA	739	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	1	0	0	N
FLT3	RTMIWILFA	ENDOMETRIUM	307	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	Y	5	12	0	N
FLT3	SACQASCFS	LUNG	446	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	1	0	0	N
FLT3	SDQISGLHE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	749	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	0	0	0	N
FLT3	SEREALMSV	LUNG	653	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	Y	6	10	0	N
FLT3	SFHNLTSFL	LUNG	935	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	Y	9	11	0	N
FLT3	SFLGCQLTD	LARGE_INTESTINE	941	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
FLT3	SGLHENSFH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	753	p.G757E	c.2270G>A	Missense_Mutation	1	0.11	DAUDI	N	0	0	0	N
FLT3	SGVHRDLAA	LUNG	806	p.C807G	c.2419T>G	Missense_Mutation	1	0.11	DMS454	N	2	0	0	N
FLT3	SHFDLQNRG	LARGE_INTESTINE	116	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	Y
FLT3	SHPNSSMHG	LUNG	731	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	0	0	0	N
FLT3	SHPNSSMPR	AUTONOMIC_GANGLIA	731	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	1	0	0	N
FLT3	SHPNSSMRG	BONE	731	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	N	0	0	0	N
FLT3	SHPNSSVPG	LARGE_INTESTINE	731	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	0	0	0	N
FLT3	SIFKFCNHK	SKIN	402	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	N	5	0	0	N
FLT3	SKRETFHRT	LARGE_INTESTINE	705	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	N	1	0	0	N
FLT3	SLNCQSHFD	LARGE_INTESTINE	111	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
FLT3	SMHGSREVQ	LUNG	736	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	N	0	0	0	N
FLT3	SMPRSREVQ	AUTONOMIC_GANGLIA	736	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	N	0	0	0	N
FLT3	SMRGSREVQ	BONE	736	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	N	0	0	0	N
FLT3	SNTGVSIQV	SKIN	633	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	1	0	0	N
FLT3	SPSITLQVL	LUNG	86	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	Y	18	9	0	N
FLT3	SRKRPSFHN	LUNG	930	p.P937H	c.2810C>A	Missense_Mutation	1	0.11	NCIH2172	N	2	0	0	N
FLT3	SSLNCQSHF	LARGE_INTESTINE	110	p.P116S	c.346C>T	Missense_Mutation	1	0.11	HT115	N	4	0	0	N
FLT3	SSMHGSREV	LUNG	735	p.P738H	c.2213C>A	Missense_Mutation	1	0.11	NCIH23	Y	4	9	0	N
FLT3	SSMPRSREV	AUTONOMIC_GANGLIA	735	p.G739R	c.2215G>C	Missense_Mutation	1	0.11	SKNAS	Y	5	11	0	Y
FLT3	SSMRGSREV	BONE	735	p.P738R	c.2213C>G	Missense_Mutation	1	0.11	MHHES1	Y	4	10	0	N
FLT3	SSVARKDTG	LUNG	318	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	N	0	0	0	N
FLT3	SSVPGSREV	LARGE_INTESTINE	735	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	Y	4	9	0	N
FLT3	STNRTMIWI	ENDOMETRIUM	304	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	Y	2	11	0	N
FLT3	SVARKDTGY	LUNG	319	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	N	2	0	0	N
FLT3	SVLKMMTQL	LUNG	660	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	N	14	0	0	N
FLT3	SVPGSREVQ	LARGE_INTESTINE	736	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	0	0	0	N
FLT3	SVRFKACPQ	PROSTATE	370	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
FLT3	SVSECPHTY	LUNG	961	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	4	0	0	N
FLT3	TAYGISNTG	SKIN	628	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	0	0	0	N
FLT3	TDAEEAMYQ	LARGE_INTESTINE	948	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
FLT3	TEGVWNTKA	LUNG	479	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	5	0	0	N
FLT3	TFHRTWTEI	LARGE_INTESTINE	709	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	Y	4	11	0	N
FLT3	TFRRPYFRK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	167	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	Y	1	12	0	N
FLT3	TKANRKVFG	LUNG	485	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	0	0	0	N
FLT3	TLLYTFRRP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	163	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	N	0	0	0	N
FLT3	TMIWILFAF	ENDOMETRIUM	308	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	N	7	0	0	N
FLT3	TNRTMIWIL	ENDOMETRIUM	305	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	Y	7	15	0	N
FLT3	TSFLGCQLT	LARGE_INTESTINE	940	p.A948T	c.2842G>A	Missense_Mutation	1	0.11	SNU1040	N	1	0	0	N
FLT3	TTEEIYIIM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	914	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	Y	4	9	0	N
FLT3	VARKDTGYY	LUNG	320	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	N	5	0	4	N
FLT3	VCTLSGPIY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	680	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	5	0	0	N
FLT3	VDGSVSECP	LUNG	958	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	0	0	0	N
FLT3	VDVSPSITL	LUNG	83	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	N	11	0	2	N
FLT3	VEVDVSPSI	LUNG	81	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	Y	9	9	4	N
FLT3	VLAEASACQ	LUNG	441	p.S448C	c.1342A>T	Missense_Mutation	1	0.11	NCIH1568	N	0	0	3	N
FLT3	VLATHGKVV	ENDOMETRIUM	817	p.V819A	c.2456T>C	Missense_Mutation	1	0.11	HEC108	N	8	0	0	N
FLT3	VLKMMTQLG	LUNG	661	p.E661V	c.1982A>T	Missense_Mutation	1	0.11	ABC1	N	0	0	12	N
FLT3	VLVNHGKVV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	817	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	N	7	0	2	N
FLT3	VMYQNVDGR	ENDOMETRIUM	953	p.A953V	c.2858C>T	Missense_Mutation	1	0.11	HEC151	N	8	0	5	N
FLT3	VNHGKVVKI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	819	p.T820N	c.2459C>A	Missense_Mutation	1	0.11	ME1	Y	7	16	8	N
FLT3	VNLLGVCTL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	675	p.A680V	c.2039C>T	Missense_Mutation	1	0.11	OCIAML2	N	12	0	33	N
FLT3	VPAEASASQ	ENDOMETRIUM	441	p.L442P	c.1325T>C	Missense_Mutation	1	0.11	EN	N	1	0	1	N
FLT3	VPGSREVQI	LARGE_INTESTINE	737	p.M737V	c.2209A>G	Missense_Mutation	1	0.11	LS411N	N	14	0	0	N
FLT3	VRFKACPQI	PROSTATE	371	p.Y376C	c.1127A>G	Missense_Mutation	1	0.11	22RV1	N	7	0	28	N
FLT3	VRGNACLPV	ENDOMETRIUM	844	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	32	N
FLT3	VSPSITLQV	LUNG	85	p.A87P	c.259G>C	Missense_Mutation	1	0.11	HCC1171	N	5	0	5	N
FLT3	VSSVARKDT	LUNG	317	p.N323K	c.969C>A	Missense_Mutation	1	0.11	A549	N	1	0	0	N
FLT3	VVRGNACLP	ENDOMETRIUM	843	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	2	N
FLT3	VWNTKANRK	LUNG	482	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	0	0	2	N
FLT3	WILFAFVSS	ENDOMETRIUM	311	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	N	2	0	11	N
FLT3	WNTKANRKV	LUNG	483	p.R485T	c.1454G>C	Missense_Mutation	1	0.11	NCIH1836	N	4	0	6	N
FLT3	YGISNTGVS	SKIN	630	p.K634N	c.1902A>T	Missense_Mutation	1	0.11	IPC298	N	4	0	19	N
FLT3	YLRSKRETF	LARGE_INTESTINE	702	p.K709T	c.2126A>C	Missense_Mutation	1	0.11	SNU81	Y	10	11	5	N
FLT3	YQNVDGSVS	LUNG	955	p.R961S	c.2881C>A	Missense_Mutation	1	0.11	HCC1359	N	2	0	7	N
FLT3	YSIFKFCNH	SKIN	401	p.S404F	c.1211C>T	Missense_Mutation	1	0.11	MDAMB435S	Y	2	10	1	N
FLT3	YSTNRTMIW	ENDOMETRIUM	303	p.R311W	c.931C>T	Missense_Mutation	1	0.11	HEC1B	N	6	0	3	Y
FLT3	YTFRRPYFR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	166	p.L168F	c.504A>C	Missense_Mutation	1	0.11	WSUDLCL2	Y	9	11	4	Y
FLT3	YTTEEIYII	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	913	p.A914T	c.2740G>A	Missense_Mutation	1	0.11	BCP1	N	11	0	0	N
FLT3	YVVRGNACL	ENDOMETRIUM	842	p.R849C	c.2545C>T	Missense_Mutation	1	0.11	HEC6	N	12	0	12	N
FLT3	ADFREYEYD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	592	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	N	0	0	0	N
FLT3	ADFREYEYD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	592	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	N	0	0	0	N
FLT3	ALCDSQGES	ENDOMETRIUM	197	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	0	0	0	N
FLT3	ALCDSQGES	LARGE_INTESTINE	197	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	0	0	0	N
FLT3	AQFTKMFML	OVARY	425	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	Y	22	9	0	N
FLT3	AQFTKMFML	LIVER	425	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	Y	22	9	0	N
FLT3	CSSSKHLSQ	PANCREAS	330	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	0	0	0	N
FLT3	CSSSKHLSQ	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	330	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	0	0	0	N
FLT3	DAQFTKMFM	OVARY	424	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	N	4	0	0	Y
FLT3	DAQFTKMFM	LIVER	424	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	N	4	0	0	Y
FLT3	DNEYFYADF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	586	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	N	4	0	0	N
FLT3	DNEYFYADF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	586	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	N	4	0	0	N
FLT3	EPIVEWALC	ENDOMETRIUM	191	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	4	0	0	N
FLT3	EPIVEWALC	LARGE_INTESTINE	191	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	4	0	0	N
FLT3	EWALCDSQG	ENDOMETRIUM	195	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	0	0	0	N
FLT3	EWALCDSQG	LARGE_INTESTINE	195	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	0	0	0	N
FLT3	EYFYADFRE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	588	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	N	0	0	0	N
FLT3	EYFYADFRE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	588	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	N	0	0	0	N
FLT3	FMLNIRRKP	OVARY	431	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	N	2	0	15	N
FLT3	FMLNIRRKP	LIVER	431	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	N	2	0	15	N
FLT3	FTKMFMLNI	OVARY	427	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	Y	7	15	6	N
FLT3	FTKMFMLNI	LIVER	427	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	Y	7	15	6	N
FLT3	FYADFREYE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	590	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	N	2	0	2	N
FLT3	FYADFREYE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	590	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	N	2	0	2	N
FLT3	HLSQSALVT	PANCREAS	335	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	1	0	0	N
FLT3	HLSQSALVT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	335	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	1	0	0	N
FLT3	IVEWALCDS	ENDOMETRIUM	193	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	1	0	11	N
FLT3	IVEWALCDS	LARGE_INTESTINE	193	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	1	0	11	N
FLT3	KHLSQSALV	PANCREAS	334	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	4	0	0	N
FLT3	KHLSQSALV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	334	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	4	0	0	N
FLT3	KMFMLNIRR	OVARY	429	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	Y	8	9	0	N
FLT3	KMFMLNIRR	LIVER	429	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	Y	8	9	0	N
FLT3	LSQSALVTI	PANCREAS	336	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	7	0	2	N
FLT3	LSQSALVTI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	336	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	7	0	2	N
FLT3	MFMLNIRRK	OVARY	430	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	Y	0	12	25	N
FLT3	MFMLNIRRK	LIVER	430	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	Y	0	12	25	N
FLT3	MLNIRRKPQ	OVARY	432	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	N	0	0	22	N
FLT3	MLNIRRKPQ	LIVER	432	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	N	0	0	22	N
FLT3	NEYFYADFR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	587	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	Y	1	10	0	N
FLT3	NEYFYADFR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	587	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	Y	1	10	0	N
FLT3	PEPIVEWAL	ENDOMETRIUM	190	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	Y	4	11	0	Y
FLT3	PEPIVEWAL	LARGE_INTESTINE	190	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	Y	4	11	0	Y
FLT3	PIVEWALCD	ENDOMETRIUM	192	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	0	0	0	N
FLT3	PIVEWALCD	LARGE_INTESTINE	192	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	0	0	0	N
FLT3	QFTKMFMLN	OVARY	426	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	N	0	0	0	N
FLT3	QFTKMFMLN	LIVER	426	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	N	0	0	0	N
FLT3	SDNEYFYAD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	585	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	N	0	0	0	N
FLT3	SDNEYFYAD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	585	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	N	0	0	0	N
FLT3	SKHLSQSAL	PANCREAS	333	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	4	0	0	N
FLT3	SKHLSQSAL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	333	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	4	0	0	N
FLT3	SSDNEYFYA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	584	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	N	2	0	0	N
FLT3	SSDNEYFYA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	584	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	N	2	0	0	N
FLT3	SSKHLSQSA	PANCREAS	332	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	1	0	0	N
FLT3	SSKHLSQSA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	332	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	1	0	0	N
FLT3	SSSKHLSQS	PANCREAS	331	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	1	0	0	N
FLT3	SSSKHLSQS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	331	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	1	0	0	N
FLT3	TCSSSKHLS	PANCREAS	329	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	0	0	0	N
FLT3	TCSSSKHLS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	329	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	0	0	0	N
FLT3	TKMFMLNIR	OVARY	428	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	RMUGS	N	1	0	0	N
FLT3	TKMFMLNIR	LIVER	428	p.T432M	c.1295C>T	Missense_Mutation	1	0.22	SNU475	N	1	0	0	N
FLT3	VEWALCDSQ	ENDOMETRIUM	194	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	0	0	0	N
FLT3	VEWALCDSQ	LARGE_INTESTINE	194	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	0	0	0	N
FLT3	VPEPIVEWA	ENDOMETRIUM	189	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	6	0	0	Y
FLT3	VPEPIVEWA	LARGE_INTESTINE	189	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	6	0	0	Y
FLT3	WALCDSQGE	ENDOMETRIUM	196	p.V197A	c.590T>C	Missense_Mutation	1	0.22	EN	N	2	0	1	N
FLT3	WALCDSQGE	LARGE_INTESTINE	196	p.V197A	c.590T>C	Missense_Mutation	1	0.22	HCT116	N	2	0	1	N
FLT3	YADFREYEY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	591	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	Y	6	14	0	N
FLT3	YADFREYEY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	591	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	Y	6	14	0	N
FLT3	YFYADFREY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	589	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC1	N	5	0	2	N
FLT3	YFYADFREY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	589	p.V592A	c.1775T>C	Missense_Mutation	1	0.22	MONOMAC6	N	5	0	2	N
FLT3	YTCSSSKHL	PANCREAS	328	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	KP3	N	9	0	2	N
FLT3	YTCSSSKHL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	328	p.P336L	c.1007C>T	Missense_Mutation	1	0.22	PL21	N	9	0	2	N