Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
PDE4DIP	ASLSPSINQ	LUNG	2083	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	BEN	N	0	0	0	N
PDE4DIP	ASLSPSINQ	PLEURA	2083	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	MPP89	N	0	0	0	N
PDE4DIP	ASLSPSINQ	PLEURA	2083	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	NCIH2452	N	0	0	0	N
PDE4DIP	ASLSPSINQ	UPPER_AERODIGESTIVE_TRACT	2083	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	SCC15	N	0	0	0	N
PDE4DIP	ASLSPSINQ	SKIN	2083	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	WM983B	N	0	0	0	N
PDE4DIP	GKASLSPSI	LUNG	2081	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	BEN	N	2	0	0	N
PDE4DIP	GKASLSPSI	PLEURA	2081	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	MPP89	N	2	0	0	N
PDE4DIP	GKASLSPSI	PLEURA	2081	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	NCIH2452	N	2	0	0	N
PDE4DIP	GKASLSPSI	UPPER_AERODIGESTIVE_TRACT	2081	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	SCC15	N	2	0	0	N
PDE4DIP	GKASLSPSI	SKIN	2081	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	WM983B	N	2	0	0	N
PDE4DIP	KASLSPSIN	LUNG	2082	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	BEN	N	1	0	0	Y
PDE4DIP	KASLSPSIN	PLEURA	2082	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	MPP89	N	1	0	0	Y
PDE4DIP	KASLSPSIN	PLEURA	2082	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	NCIH2452	N	1	0	0	Y
PDE4DIP	KASLSPSIN	UPPER_AERODIGESTIVE_TRACT	2082	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	SCC15	N	1	0	0	Y
PDE4DIP	KASLSPSIN	SKIN	2082	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	WM983B	N	1	0	0	Y
PDE4DIP	LSPSINQNF	LUNG	2085	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	BEN	N	8	0	0	N
PDE4DIP	LSPSINQNF	PLEURA	2085	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	MPP89	N	8	0	0	N
PDE4DIP	LSPSINQNF	PLEURA	2085	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	NCIH2452	N	8	0	0	N
PDE4DIP	LSPSINQNF	UPPER_AERODIGESTIVE_TRACT	2085	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	SCC15	N	8	0	0	N
PDE4DIP	LSPSINQNF	SKIN	2085	p.S2089del	c.6265_6267delTCC	In_Frame_Del	3	0.55	WM983B	N	8	0	0	N
PDE4DIP	PSINQNFPA	LUNG	2087	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	BEN	N	0	0	0	N
PDE4DIP	PSINQNFPA	PLEURA	2087	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	MPP89	N	0	0	0	N
PDE4DIP	PSINQNFPA	PLEURA	2087	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	NCIH2452	N	0	0	0	N
PDE4DIP	PSINQNFPA	UPPER_AERODIGESTIVE_TRACT	2087	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	SCC15	N	0	0	0	N
PDE4DIP	PSINQNFPA	SKIN	2087	p.S2089del	c.6265_6267delTCC	In_Frame_Del	1	0.55	WM983B	N	0	0	0	N
PDE4DIP	SLSPSINQN	LUNG	2084	p.S2089del	c.6265_6267delTCC	In_Frame_Del	4	0.55	BEN	N	0	0	0	N
PDE4DIP	SLSPSINQN	PLEURA	2084	p.S2089del	c.6265_6267delTCC	In_Frame_Del	4	0.55	MPP89	N	0	0	0	N
PDE4DIP	SLSPSINQN	PLEURA	2084	p.S2089del	c.6265_6267delTCC	In_Frame_Del	4	0.55	NCIH2452	N	0	0	0	N
PDE4DIP	SLSPSINQN	UPPER_AERODIGESTIVE_TRACT	2084	p.S2089del	c.6265_6267delTCC	In_Frame_Del	4	0.55	SCC15	N	0	0	0	N
PDE4DIP	SLSPSINQN	SKIN	2084	p.S2089del	c.6265_6267delTCC	In_Frame_Del	4	0.55	WM983B	N	0	0	0	N
PDE4DIP	SPSINQNFP	LUNG	2086	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	BEN	N	0	0	0	N
PDE4DIP	SPSINQNFP	PLEURA	2086	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	MPP89	N	0	0	0	N
PDE4DIP	SPSINQNFP	PLEURA	2086	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	NCIH2452	N	0	0	0	N
PDE4DIP	SPSINQNFP	UPPER_AERODIGESTIVE_TRACT	2086	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	SCC15	N	0	0	0	N
PDE4DIP	SPSINQNFP	SKIN	2086	p.S2089del	c.6265_6267delTCC	In_Frame_Del	2	0.55	WM983B	N	0	0	0	N