Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
MAP3K4AAAAAAAASSTOMACH1194p.V1200delc.3597_3599delTGTIn_Frame_Del10.11SNU520N100Y
MAP3K4AAAAAAASRSTOMACH1195p.V1200delc.3597_3599delTGTIn_Frame_Del10.11SNU520N300N
MAP3K4AAAAAASRPSTOMACH1196p.V1200delc.3597_3599delTGTIn_Frame_Del10.11SNU520N000N
MAP3K4AAAAASRPSSTOMACH1197p.V1200delc.3597_3599delTGTIn_Frame_Del10.11SNU520N100N
MAP3K4AAAASRPSPSTOMACH1198p.V1200delc.3597_3599delTGTIn_Frame_Del10.11SNU520N000N
MAP3K4AAASRPSPSSTOMACH1199p.V1200delc.3597_3599delTGTIn_Frame_Del10.11SNU520N100N