Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
VHLEIWKTTQMCKIDNEY186p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN100N
VHLFLPISHCQCKIDNEY146p.V142fsc.426_429delTGACFrame_Shift_Del70.11A498N504N
VHLIWKTTQMCRKIDNEY187p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN200N
VHLKTTQMCRKTKIDNEY189p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN100N
VHLPISHCQCILKIDNEY148p.V142fsc.426_429delTGACFrame_Shift_Del70.11A498N000N
VHLQMCRKTWSGKIDNEY192p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN000N
VHLTQMCRKTWSKIDNEY191p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN000N
VHLTTQMCRKTWKIDNEY190p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN100N
VHLWKTTQMCRKKIDNEY188p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN302N
VHLYEIWKTTQMKIDNEY185p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN10015N