Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
TTBK1FSALPEGEQLARGE_INTESTINE448p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4N200N
TTBK1HNPSPFSALLARGE_INTESTINE443p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4Y10140N
TTBK1LPHNPSPFSLARGE_INTESTINE441p.A437fsc.1309_1310insCFrame_Shift_Ins40.11SNUC4N500N
TTBK1NPSPFSALPLARGE_INTESTINE444p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4N000N
TTBK1PFSALPEGELARGE_INTESTINE447p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4N000N
TTBK1PHNPSPFSALARGE_INTESTINE442p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4N000N
TTBK1PRLPHNPSPLARGE_INTESTINE439p.A437fsc.1309_1310insCFrame_Shift_Ins40.11SNUC4N000N
TTBK1PSPFSALPELARGE_INTESTINE445p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4N000N
TTBK1RAPPRLPHNLARGE_INTESTINE436p.A437fsc.1309_1310insCFrame_Shift_Ins40.11SNUC4N300N
TTBK1RLPHNPSPFLARGE_INTESTINE440p.A437fsc.1309_1310insCFrame_Shift_Ins40.11SNUC4N900N
TTBK1SALPEGEQPLARGE_INTESTINE449p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4N000N
TTBK1SPFSALPEGLARGE_INTESTINE446p.A437fsc.1309_1310insCFrame_Shift_Ins50.11SNUC4N100N