Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
SMAD4AAIVKDCCRUPPER_AERODIGESTIVE_TRACT231p.L229fsc.687_687delGFrame_Shift_Del50.11PECAPJ34CLONEC12N400N
SMAD4ADCRPTTFRBILIARY_TRACT539p.V539fsc.1615_1628delGTACTTCATACCATFrame_Shift_Del70.11SNU245N100N
SMAD4AIFSTTRLCPANCREAS282p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4AITTMELILOVARY60p.T63fsc.189_189delAFrame_Shift_Del50.11JHOM2BN500N
SMAD4ALPPGLEVGPANCREAS260p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N000N
SMAD4CLTTKTAIFPANCREAS276p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N500N
SMAD4CRPIPDITGPANCREAS290p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N100N
SMAD4DCRPTTFRLBILIARY_TRACT540p.V539fsc.1615_1628delGTACTTCATACCATFrame_Shift_Del60.11SNU245Y5100N
SMAD4DEADCRPTTBILIARY_TRACT537p.V539fsc.1615_1628delGTACTTCATACCATFrame_Shift_Del50.11SNU245N500N
SMAD4DITGLFTMSPANCREAS295p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4EADCRPTTFBILIARY_TRACT538p.V539fsc.1615_1628delGTACTTCATACCATFrame_Shift_Del60.11SNU245Y490N
SMAD4EHWMGGFRWOVARY76p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN200N
SMAD4EKLGVHLEMPANCREAS415p.L414fsc.1242_1245delAGACFrame_Shift_Del50.11KP2N400N
SMAD4ELILVNVLPOVARY65p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN000N
SMAD4EMLFIRSTQPANCREAS422p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2N100N
SMAD4EVGLHHTHLPANCREAS266p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N500N
SMAD4FIRSTQVHIPANCREAS425p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2N806N
SMAD4FPIILLLSIPANCREAS310p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N16018N
SMAD4FRWLVGKDFOVARY82p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN6011N
SMAD4FSTTRLCRPPANCREAS284p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N200N
SMAD4FTMSLHSSLPANCREAS300p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N1402N
SMAD4GAAIVKDCCUPPER_AERODIGESTIVE_TRACT230p.L229fsc.687_687delGFrame_Shift_Del60.11PECAPJ34CLONEC12N300N
SMAD4GFRWLVGKDOVARY81p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN000N
SMAD4GGFRWLVGKOVARY80p.T63fsc.189_189delAFrame_Shift_Del50.11JHOM2BN200N
SMAD4GLEVGLHHTPANCREAS264p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N200N
SMAD4GLFTMSLHSPANCREAS298p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N200N
SMAD4GLHHTHLICPANCREAS268p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N200N
SMAD4GQQLVSQLLPANCREAS247p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N1100N
SMAD4GVHLEMLFIPANCREAS418p.L414fsc.1242_1245delAGACFrame_Shift_Del50.11KP2Y6120N
SMAD4GVPLLTLKWPANCREAS319p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N100N
SMAD4HHTHLICLTPANCREAS270p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N100N
SMAD4HLEMLFIRSPANCREAS420p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2N100N
SMAD4HLICLTTKTPANCREAS273p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N200N
SMAD4HSSLPFPIIPANCREAS305p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N800N
SMAD4HTHLICLTTPANCREAS271p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N100N
SMAD4HWMGGFRWLOVARY77p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BY8130N
SMAD4ICLTTKTAIPANCREAS275p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N902N
SMAD4IFSTTRLCRPANCREAS283p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N202N
SMAD4IGVPLLTLKPANCREAS318p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N000N
SMAD4IILLLSIGVPANCREAS312p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N8024N
SMAD4IITALPPGLPANCREAS257p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N602N
SMAD4ILGAAIVKDUPPER_AERODIGESTIVE_TRACT228p.L229fsc.687_687delGFrame_Shift_Del50.11PECAPJ34CLONEC12N001N
SMAD4ILLLSIGVPPANCREAS313p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N006N
SMAD4ILVNVLPYROVARY67p.T63fsc.189_189delAFrame_Shift_Del50.11JHOM2BN501N
SMAD4IPDITGLFTPANCREAS293p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N600N
SMAD4ITALPPGLEPANCREAS258p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4ITGLFTMSLPANCREAS296p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2Y101115N
SMAD4ITTMELILVOVARY61p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN500N
SMAD4KLGVHLEMLPANCREAS416p.L414fsc.1242_1245delAGACFrame_Shift_Del50.11KP2Y16120N
SMAD4KTAIFSTTRPANCREAS280p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2Y690N
SMAD4LCRPIPDITPANCREAS289p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4LDEADCRPTBILIARY_TRACT536p.V539fsc.1615_1628delGTACTTCATACCATFrame_Shift_Del50.11SNU245N100N
SMAD4LEKLGVHLEPANCREAS414p.L414fsc.1242_1245delAGACFrame_Shift_Del50.11KP2N004N
SMAD4LEMLFIRSTPANCREAS421p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2N5011N
SMAD4LEVGLHHTHPANCREAS265p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N100N
SMAD4LFIRSTQVHPANCREAS424p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2N0019N
SMAD4LFTMSLHSSPANCREAS299p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N0022N
SMAD4LGAAIVKDCUPPER_AERODIGESTIVE_TRACT229p.L229fsc.687_687delGFrame_Shift_Del60.11PECAPJ34CLONEC12N000N
SMAD4LGVHLEMLFPANCREAS417p.L414fsc.1242_1245delAGACFrame_Shift_Del50.11KP2N800N
SMAD4LHHTHLICLPANCREAS269p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N802N
SMAD4LHSSLPFPIPANCREAS304p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N607N
SMAD4LICLTTKTAPANCREAS274p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N1019N
SMAD4LILVNVLPYOVARY66p.T63fsc.189_189delAFrame_Shift_Del50.11JHOM2BN11040N
SMAD4LLDEADCRPBILIARY_TRACT535p.V539fsc.1615_1628delGTACTTCATACCATFrame_Shift_Del50.11SNU245N000N
SMAD4LLLSIGVPLPANCREAS314p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N1904N
SMAD4LLSIGVPLLPANCREAS315p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N12014N
SMAD4LLTIITALPPANCREAS254p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N006N
SMAD4LLTLKWMFRPANCREAS322p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N600N
SMAD4LPFPIILLLPANCREAS308p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2Y30100N
SMAD4LPPGLEVGLPANCREAS261p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N1900N
SMAD4LPYREHWMGOVARY72p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN300N
SMAD4LSIGVPLLTPANCREAS316p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4LTIITALPPPANCREAS255p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N008N
SMAD4LTTKTAIFSPANCREAS277p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N004N
SMAD4LVNVLPYREOVARY68p.T63fsc.189_189delAFrame_Shift_Del50.11JHOM2BN0010N
SMAD4LVSQLLTIIPANCREAS250p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N8014N
SMAD4MELILVNVLOVARY64p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BY13913N
SMAD4MGGFRWLVGOVARY79p.T63fsc.189_189delAFrame_Shift_Del50.11JHOM2BN002N
SMAD4MLFIRSTQVPANCREAS423p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2Y15915N
SMAD4MSLHSSLPFPANCREAS302p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N9012N
SMAD4NVLPYREHWOVARY70p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BY190N
SMAD4PDITGLFTMPANCREAS294p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N100N
SMAD4PFPIILLLSPANCREAS309p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N000N
SMAD4PGLEVGLHHPANCREAS263p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4PGQQLVSQLPANCREAS246p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4PIILLLSIGPANCREAS311p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4PIPDITGLFPANCREAS292p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4PLLTLKWMFPANCREAS321p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N300N
SMAD4PPGLEVGLHPANCREAS262p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N000N
SMAD4PYREHWMGGOVARY73p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN000N
SMAD4QLLTIITALPANCREAS253p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N1800N
SMAD4QLVSQLLTIPANCREAS249p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2Y11110N
SMAD4QQLVSQLLTPANCREAS248p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N300N
SMAD4REHWMGGFROVARY75p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN100N
SMAD4RLCRPIPDIPANCREAS288p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2Y9150N
SMAD4RPIPDITGLPANCREAS291p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2Y2290N
SMAD4RWLVGKDFLOVARY83p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN900N
SMAD4SIGVPLLTLPANCREAS317p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2Y590N
SMAD4SILGAAIVKUPPER_AERODIGESTIVE_TRACT227p.L229fsc.687_687delGFrame_Shift_Del50.11PECAPJ34CLONEC12N400N
SMAD4SLHSSLPFPPANCREAS303p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4SLPFPIILLPANCREAS307p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2Y15100N
SMAD4SQLLTIITAPANCREAS252p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2Y490N
SMAD4SSLPFPIILPANCREAS306p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2Y1890N
SMAD4STTRLCRPIPANCREAS285p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N300N
SMAD4SYYLEKLGVPANCREAS411p.L414fsc.1242_1245delAGACFrame_Shift_Del50.11KP2N500N
SMAD4TAIFSTTRLPANCREAS281p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2Y16100N
SMAD4TALPPGLEVPANCREAS259p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N700N
SMAD4TGLFTMSLHPANCREAS297p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4THLICLTTKPANCREAS272p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4TIITALPPGPANCREAS256p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4TKTAIFSTTPANCREAS279p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4TMELILVNVOVARY63p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN600N
SMAD4TMSLHSSLPPANCREAS301p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N000N
SMAD4TRLCRPIPDPANCREAS287p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N200N
SMAD4TTKTAIFSTPANCREAS278p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4TTMELILVNOVARY62p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN100N
SMAD4TTRLCRPIPPANCREAS286p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N000N
SMAD4VGLHHTHLIPANCREAS267p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N11020N
SMAD4VHLEMLFIRPANCREAS419p.L414fsc.1242_1245delAGACFrame_Shift_Del50.11KP2N202N
SMAD4VLPYREHWMOVARY71p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN702N
SMAD4VNVLPYREHOVARY69p.T63fsc.189_189delAFrame_Shift_Del50.11JHOM2BN001N
SMAD4VPLLTLKWMPANCREAS320p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del60.11TCCPAN2N1300N
SMAD4VSQLLTIITPANCREAS251p.Q250fsc.748_760delCAGAATGGATTTAFrame_Shift_Del50.11TCCPAN2N100N
SMAD4WLVGKDFLMOVARY84p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BY1090N
SMAD4WMGGFRWLVOVARY78p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BY8101N
SMAD4YLEKLGVHLPANCREAS413p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2Y13110N
SMAD4YREHWMGGFOVARY74p.T63fsc.189_189delAFrame_Shift_Del60.11JHOM2BN600N
SMAD4YYLEKLGVHPANCREAS412p.L414fsc.1242_1245delAGACFrame_Shift_Del60.11KP2N201N