Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
NF1AADDDVNVLENDOMETRIUM1056p.V1061fsc.3183_3183delAFrame_Shift_Del20.11HEC59Y1390N
NF1ADDDVNVLQENDOMETRIUM1057p.V1061fsc.3183_3183delAFrame_Shift_Del30.11HEC59N100N
NF1AGCSGTPRFLARGE_INTESTINE671p.T676fsc.2027_2027delCFrame_Shift_Del20.11HCT116Y590N
NF1ALLEQTCILLARGE_INTESTINE2336p.Q2340fsc.7019_7019delAFrame_Shift_Del40.11RKOY20100N
NF1CSGTPRFADLARGE_INTESTINE673p.T676fsc.2027_2027delCFrame_Shift_Del40.11HCT116N000N
NF1DDDVNVLQEENDOMETRIUM1058p.V1061fsc.3183_3183delAFrame_Shift_Del40.11HEC59N000N
NF1DDVNVLQEIENDOMETRIUM1059p.V1061fsc.3183_3183delAFrame_Shift_Del50.11HEC59N600Y
NF1DEFINEFFMCENTRAL_NERVOUS_SYSTEM2632p.D2635fsc.7903_7903delGFrame_Shift_Del50.11KALS1Y890N
NF1DSMQTLFEASOFT_TISSUE1269p.F1275fsc.3825_3825delCFrame_Shift_Del20.11SKLMS1N100N
NF1DVNVLQEIWENDOMETRIUM1060p.V1061fsc.3183_3183delAFrame_Shift_Del50.11HEC59N000N
NF1EFINEFFMNCENTRAL_NERVOUS_SYSTEM2633p.D2635fsc.7903_7903delGFrame_Shift_Del50.11KALS1N000N
NF1EIWTRQAWKENDOMETRIUM1066p.V1061fsc.3183_3183delAFrame_Shift_Del60.11HEC59Y4130N
NF1FEATAWPVKSOFT_TISSUE1275p.F1275fsc.3825_3825delCFrame_Shift_Del60.11SKLMS1N300N
NF1FINEFFMNTCENTRAL_NERVOUS_SYSTEM2634p.D2635fsc.7903_7903delGFrame_Shift_Del50.11KALS1Y4113N
NF1GCSGTPRFALARGE_INTESTINE672p.T676fsc.2027_2027delCFrame_Shift_Del30.11HCT116N000N
NF1GTALLEQTCLARGE_INTESTINE2334p.Q2340fsc.7019_7019delAFrame_Shift_Del20.11RKON100N
NF1GTPRFADKPLARGE_INTESTINE675p.T676fsc.2027_2027delCFrame_Shift_Del50.11HCT116N000N
NF1IWTRQAWKQENDOMETRIUM1067p.V1061fsc.3183_3183delAFrame_Shift_Del50.11HEC59N001N
NF1KYTTDEFINCENTRAL_NERVOUS_SYSTEM2628p.D2635fsc.7903_7903delGFrame_Shift_Del20.11KALS1N200N
NF1LFEATAWPVSOFT_TISSUE1274p.F1275fsc.3825_3825delCFrame_Shift_Del50.11SKLMS1N400N
NF1LQEIWTRQAENDOMETRIUM1064p.V1061fsc.3183_3183delAFrame_Shift_Del50.11HEC59N103N
NF1MQTLFEATASOFT_TISSUE1271p.F1275fsc.3825_3825delCFrame_Shift_Del40.11SKLMS1N600N
NF1NVLQEIWTRENDOMETRIUM1062p.V1061fsc.3183_3183delAFrame_Shift_Del50.11HEC59Y690N
NF1PRFADKPRPLARGE_INTESTINE677p.T676fsc.2027_2027delCFrame_Shift_Del50.11HCT116N000N
NF1QAADDDVNVENDOMETRIUM1055p.V1061fsc.3183_3183delAFrame_Shift_Del20.11HEC59Y6110N
NF1QEIWTRQAWENDOMETRIUM1065p.V1061fsc.3183_3183delAFrame_Shift_Del60.11HEC59Y590N
NF1QTLFEATAWSOFT_TISSUE1272p.F1275fsc.3825_3825delCFrame_Shift_Del40.11SKLMS1N100N
NF1RDDLSFSKRLUNG1026p.C1032fsc.3095_3095delGFrame_Shift_Del30.11HCC1359N000N
NF1RFADKPRPNLARGE_INTESTINE678p.T676fsc.2027_2027delCFrame_Shift_Del50.11HCT116N100N
NF1RRDDLSFSKLUNG1025p.C1032fsc.3095_3095delGFrame_Shift_Del20.11HCC1359Y4100N
NF1SGTPRFADKLARGE_INTESTINE674p.T676fsc.2027_2027delCFrame_Shift_Del50.11HCT116N000N
NF1SMQTLFEATSOFT_TISSUE1270p.F1275fsc.3825_3825delCFrame_Shift_Del30.11SKLMS1N300N
NF1TALLEQTCILARGE_INTESTINE2335p.Q2340fsc.7019_7019delAFrame_Shift_Del30.11RKON800N
NF1TDEFINEFFCENTRAL_NERVOUS_SYSTEM2631p.D2635fsc.7903_7903delGFrame_Shift_Del50.11KALS1N400N
NF1TLFEATAWPSOFT_TISSUE1273p.F1275fsc.3825_3825delCFrame_Shift_Del50.11SKLMS1N100N
NF1TPRFADKPRLARGE_INTESTINE676p.T676fsc.2027_2027delCFrame_Shift_Del50.11HCT116N400N
NF1TTDEFINEFCENTRAL_NERVOUS_SYSTEM2630p.D2635fsc.7903_7903delGFrame_Shift_Del40.11KALS1Y690N
NF1VLQEIWTRQENDOMETRIUM1063p.V1061fsc.3183_3183delAFrame_Shift_Del50.11HEC59N000N
NF1VNVLQEIWTENDOMETRIUM1061p.V1061fsc.3183_3183delAFrame_Shift_Del40.11HEC59N000N
NF1YTTDEFINECENTRAL_NERVOUS_SYSTEM2629p.D2635fsc.7903_7903delGFrame_Shift_Del30.11KALS1N200N
NF1ARVLVTLILCENTRAL_NERVOUS_SYSTEM1240p.L1246fsc.3737_3740delTGTTFrame_Shift_Del20.22TM31Y9100N
NF1ARVLVTLILCENTRAL_NERVOUS_SYSTEM1240p.L1246fsc.3737_3740delTGTTFrame_Shift_Del20.22U87MGY9100N
NF1CSGTCFLKKCENTRAL_NERVOUS_SYSTEM1255p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31N300Y
NF1CSGTCFLKKCENTRAL_NERVOUS_SYSTEM1255p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGN300Y
NF1GIYSTNCSGCENTRAL_NERVOUS_SYSTEM1249p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22TM31N000N
NF1GIYSTNCSGCENTRAL_NERVOUS_SYSTEM1249p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22U87MGN000N
NF1ILGIYSTNCCENTRAL_NERVOUS_SYSTEM1247p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22TM31N4010N
NF1ILGIYSTNCCENTRAL_NERVOUS_SYSTEM1247p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22U87MGN4010N
NF1IYSTNCSGTCENTRAL_NERVOUS_SYSTEM1250p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31N200N
NF1IYSTNCSGTCENTRAL_NERVOUS_SYSTEM1250p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGN200N
NF1LGIYSTNCSCENTRAL_NERVOUS_SYSTEM1248p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22TM31N0034N
NF1LGIYSTNCSCENTRAL_NERVOUS_SYSTEM1248p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22U87MGN0034N
NF1LILGIYSTNCENTRAL_NERVOUS_SYSTEM1246p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22TM31N000Y
NF1LILGIYSTNCENTRAL_NERVOUS_SYSTEM1246p.L1246fsc.3737_3740delTGTTFrame_Shift_Del60.22U87MGN000Y
NF1LVTLILGIYCENTRAL_NERVOUS_SYSTEM1243p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31N609N
NF1LVTLILGIYCENTRAL_NERVOUS_SYSTEM1243p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGN609N
NF1NCSGTCFLKCENTRAL_NERVOUS_SYSTEM1254p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31N200N
NF1NCSGTCFLKCENTRAL_NERVOUS_SYSTEM1254p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGN200N
NF1RVLVTLILGCENTRAL_NERVOUS_SYSTEM1241p.L1246fsc.3737_3740delTGTTFrame_Shift_Del30.22TM31N000N
NF1RVLVTLILGCENTRAL_NERVOUS_SYSTEM1241p.L1246fsc.3737_3740delTGTTFrame_Shift_Del30.22U87MGN000N
NF1STNCSGTCFCENTRAL_NERVOUS_SYSTEM1252p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31Y490Y
NF1STNCSGTCFCENTRAL_NERVOUS_SYSTEM1252p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGY490Y
NF1TLILGIYSTCENTRAL_NERVOUS_SYSTEM1245p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31N400N
NF1TLILGIYSTCENTRAL_NERVOUS_SYSTEM1245p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGN400N
NF1TNCSGTCFLCENTRAL_NERVOUS_SYSTEM1253p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31Y5110N
NF1TNCSGTCFLCENTRAL_NERVOUS_SYSTEM1253p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGY5110N
NF1VLVTLILGICENTRAL_NERVOUS_SYSTEM1242p.L1246fsc.3737_3740delTGTTFrame_Shift_Del40.22TM31N16012N
NF1VLVTLILGICENTRAL_NERVOUS_SYSTEM1242p.L1246fsc.3737_3740delTGTTFrame_Shift_Del40.22U87MGN16012N
NF1VTLILGIYSCENTRAL_NERVOUS_SYSTEM1244p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31N0010N
NF1VTLILGIYSCENTRAL_NERVOUS_SYSTEM1244p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGN0010N
NF1YSTNCSGTCCENTRAL_NERVOUS_SYSTEM1251p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22TM31N300Y
NF1YSTNCSGTCCENTRAL_NERVOUS_SYSTEM1251p.L1246fsc.3737_3740delTGTTFrame_Shift_Del50.22U87MGN300Y
NF1AGNPIFLLCLARGE_INTESTINE1601p.I1605fsc.4813_4814insTFrame_Shift_Ins30.11SNU1040Y0100N
NF1CCTEVQNWSLARGE_INTESTINE1609p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N000N
NF1CGLCKIKTTLUNG185p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N200Y
NF1CKIKTTPEGLUNG188p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N000N
NF1CSGTPPDLPLARGE_INTESTINE673p.T676fsc.2026_2027insCFrame_Shift_Ins30.11SNUC4N000Y
NF1CTEVQNWSNLARGE_INTESTINE1610p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N100N
NF1CVPLFIPGNENDOMETRIUM1364p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N000N
NF1DLPTSPDQTLARGE_INTESTINE679p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N200N
NF1DQTRSGPVHLARGE_INTESTINE685p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000N
NF1EFPPSTSKCENDOMETRIUM1356p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N100N
NF1ELLQYIQCGLUNG178p.I183fsc.548_549insAFrame_Shift_Ins30.11NCIH1838N100N
NF1EVLTKNPSTENDOMETRIUM1181p.T1184fsc.3551_3552insAFrame_Shift_Ins40.11ENN200N
NF1EVQNWSNQWLARGE_INTESTINE1612p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N000N
NF1FIPGNLPLPENDOMETRIUM1368p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N201N
NF1FLLCCTEVQLARGE_INTESTINE1606p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N3023N
NF1FMEVLTKNPENDOMETRIUM1179p.T1184fsc.3551_3552insAFrame_Shift_Ins20.11ENN200N
NF1FPPSTSKCVENDOMETRIUM1357p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N1402N
NF1GCSGTPPDLLARGE_INTESTINE672p.T676fsc.2026_2027insCFrame_Shift_Ins20.11SNUC4N500Y
NF1GLCKIKTTPLUNG186p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N000N
NF1GNPIFLLCCLARGE_INTESTINE1602p.I1605fsc.4813_4814insTFrame_Shift_Ins40.11SNU1040N000N
NF1GPVHVSVEPLARGE_INTESTINE690p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000N
NF1GTPPDLPTSLARGE_INTESTINE675p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N100Y
NF1IELLQYIQCLUNG177p.I183fsc.548_549insAFrame_Shift_Ins20.11NCIH1838Y692N
NF1IFLLCCTEVLARGE_INTESTINE1605p.I1605fsc.4813_4814insTFrame_Shift_Ins40.11SNU1040Y496N
NF1IKTTPEGNSLUNG190p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N100N
NF1IPGNLPLPTENDOMETRIUM1369p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N600N
NF1IQCGLCKIKLUNG183p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N300N
NF1IRMAPSLHIBREAST460p.L466fsc.1398_1399insCFrame_Shift_Ins20.11MDAMB231N7051N
NF1KAGNPIFLLLARGE_INTESTINE1600p.I1605fsc.4813_4814insTFrame_Shift_Ins20.11SNU1040N1600N
NF1KCVPLFIPGENDOMETRIUM1363p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N100N
NF1KIKTTPEGNLUNG189p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N000N
NF1KNPSTRHRIENDOMETRIUM1185p.T1184fsc.3551_3552insAFrame_Shift_Ins50.11ENY4140Y
NF1KTTPEGNSILUNG191p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N100N
NF1LCCTEVQNWLARGE_INTESTINE1608p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N200N
NF1LCKIKTTPELUNG187p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N103N
NF1LFIPGNLPLENDOMETRIUM1367p.F1357fsc.4070_4071insCFrame_Shift_Ins40.11JHUEM1N907N
NF1LLCCTEVQNLARGE_INTESTINE1607p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N000N
NF1LLQYIQCGLLUNG179p.I183fsc.548_549insAFrame_Shift_Ins40.11NCIH1838N1604N
NF1LPTSPDQTRLARGE_INTESTINE680p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N500N
NF1LQYIQCGLCLUNG180p.I183fsc.548_549insAFrame_Shift_Ins40.11NCIH1838N5013N
NF1LTKNPSTRHENDOMETRIUM1183p.T1184fsc.3551_3552insAFrame_Shift_Ins50.11ENN000Y
NF1MEVLTKNPSENDOMETRIUM1180p.T1184fsc.3551_3552insAFrame_Shift_Ins30.11ENN4024N
NF1NPIFLLCCTLARGE_INTESTINE1603p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N400N
NF1PDLPTSPDQLARGE_INTESTINE678p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000N
NF1PDQTRSGPVLARGE_INTESTINE684p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000N
NF1PGNLPLPTEENDOMETRIUM1370p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N000N
NF1PIFLLCCTELARGE_INTESTINE1604p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N000N
NF1PLFIPGNLPENDOMETRIUM1366p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N000N
NF1PPDLPTSPDLARGE_INTESTINE677p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000Y
NF1PPSTSKCVPENDOMETRIUM1358p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N000N
NF1PSTSKCVPLENDOMETRIUM1359p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N100N
NF1PTSPDQTRSLARGE_INTESTINE681p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000N
NF1QCGLCKIKTLUNG184p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N000N
NF1QTRSGPVHVLARGE_INTESTINE686p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4Y2130N
NF1QYIQCGLCKLUNG181p.I183fsc.548_549insAFrame_Shift_Ins50.11NCIH1838N200N
NF1RSGPVHVSVLARGE_INTESTINE688p.T676fsc.2026_2027insCFrame_Shift_Ins40.11SNUC4Y5160N
NF1SEFPPSTSKENDOMETRIUM1355p.F1357fsc.4070_4071insCFrame_Shift_Ins40.11JHUEM1Y5100N
NF1SGPVHVSVELARGE_INTESTINE689p.T676fsc.2026_2027insCFrame_Shift_Ins40.11SNUC4N100N
NF1SGTPPDLPTLARGE_INTESTINE674p.T676fsc.2026_2027insCFrame_Shift_Ins40.11SNUC4N000Y
NF1SKCVPLFIPENDOMETRIUM1362p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N000N
NF1SPDQTRSGPLARGE_INTESTINE683p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000N
NF1SSEFPPSTSENDOMETRIUM1354p.F1357fsc.4070_4071insCFrame_Shift_Ins30.11JHUEM1N100N
NF1SSSEFPPSTENDOMETRIUM1353p.F1357fsc.4070_4071insCFrame_Shift_Ins20.11JHUEM1N100N
NF1STSKCVPLFENDOMETRIUM1360p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N400N
NF1TEVQNWSNQLARGE_INTESTINE1611p.I1605fsc.4813_4814insTFrame_Shift_Ins50.11SNU1040N100N
NF1TKNPSTRHRENDOMETRIUM1184p.T1184fsc.3551_3552insAFrame_Shift_Ins50.11ENN100Y
NF1TPPDLPTSPLARGE_INTESTINE676p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000Y
NF1TRSGPVHVSLARGE_INTESTINE687p.T676fsc.2026_2027insCFrame_Shift_Ins40.11SNUC4N200N
NF1TSKCVPLFIENDOMETRIUM1361p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1Y5120N
NF1TSPDQTRSGLARGE_INTESTINE682p.T676fsc.2026_2027insCFrame_Shift_Ins50.11SNUC4N000N
NF1VLTKNPSTRENDOMETRIUM1182p.T1184fsc.3551_3552insAFrame_Shift_Ins50.11ENN501N
NF1VPLFIPGNLENDOMETRIUM1365p.F1357fsc.4070_4071insCFrame_Shift_Ins50.11JHUEM1N2401N
NF1YIQCGLCKILUNG182p.I183fsc.548_549insAFrame_Shift_Ins60.11NCIH1838N902N