Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
MEN1	AARLRCQHP	PROSTATE	537	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	1	0	0	N
MEN1	ALKVAARLR	PROSTATE	533	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	Y	3	10	0	N
MEN1	AQPEALKVA	PROSTATE	529	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	4	0	0	N
MEN1	ARLRCQHPQ	PROSTATE	538	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	1	0	0	N
MEN1	AVSGPPGSL	PROSTATE	515	p.R521fs	c.1561_1561delC	Frame_Shift_Del	3	0.11	22RV1	N	5	0	0	N
MEN1	CQHPQHHHR	PROSTATE	542	p.R521fs	c.1561_1561delC	Frame_Shift_Del	7	0.11	22RV1	N	5	0	0	N
MEN1	EALKVAARL	PROSTATE	532	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	15	0	0	N
MEN1	GAVSGPPGS	PROSTATE	514	p.R521fs	c.1561_1561delC	Frame_Shift_Del	2	0.11	22RV1	N	2	0	0	N
MEN1	GLSLAQPEA	PROSTATE	525	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	4	0	0	N
MEN1	GPPGSLLGL	PROSTATE	518	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	20	0	0	N
MEN1	GSLLGLSLA	PROSTATE	521	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	3	0	0	N
MEN1	HHHRRRVQC	PROSTATE	547	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	2	0	0	N
MEN1	HHRRRVQCS	PROSTATE	548	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	1	0	0	N
MEN1	HPQHHHRRR	PROSTATE	544	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	4	0	0	N
MEN1	HRRRVQCSL	PROSTATE	549	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	Y	6	9	0	N
MEN1	KVAARLRCQ	PROSTATE	535	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	0	0	0	N
MEN1	LAQPEALKV	PROSTATE	528	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	6	0	0	N
MEN1	LGLSLAQPE	PROSTATE	524	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	0	0	0	N
MEN1	LKVAARLRC	PROSTATE	534	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	1	0	30	N
MEN1	LLGLSLAQP	PROSTATE	523	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	0	0	0	N
MEN1	LRCQHPQHH	PROSTATE	540	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	2	0	22	N
MEN1	LSLAQPEAL	PROSTATE	526	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	12	0	0	N
MEN1	PEALKVAAR	PROSTATE	531	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	0	0	0	N
MEN1	PGSLLGLSL	PROSTATE	520	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	0	0	0	N
MEN1	PPGSLLGLS	PROSTATE	519	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	0	0	0	N
MEN1	PQHHHRRRV	PROSTATE	545	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	1	0	0	N
MEN1	QCSLSRVRR	PROSTATE	554	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	Y	3	9	0	N
MEN1	QGAVSGPPG	PROSTATE	513	p.R521fs	c.1561_1561delC	Frame_Shift_Del	1	0.11	22RV1	N	0	0	0	N
MEN1	QHHHRRRVQ	PROSTATE	546	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	0	0	0	N
MEN1	QHPQHHHRR	PROSTATE	543	p.R521fs	c.1561_1561delC	Frame_Shift_Del	7	0.11	22RV1	N	1	0	0	N
MEN1	QPEALKVAA	PROSTATE	530	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	6	0	0	N
MEN1	RCQHPQHHH	PROSTATE	541	p.R521fs	c.1561_1561delC	Frame_Shift_Del	7	0.11	22RV1	N	0	0	0	N
MEN1	RLRCQHPQH	PROSTATE	539	p.R521fs	c.1561_1561delC	Frame_Shift_Del	6	0.11	22RV1	N	1	0	0	N
MEN1	RRRVQCSLS	PROSTATE	550	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	2	0	0	N
MEN1	RRVQCSLSR	PROSTATE	551	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	4	0	0	N
MEN1	RVQCSLSRV	PROSTATE	552	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	Y	3	11	0	N
MEN1	SGPPGSLLG	PROSTATE	517	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	1	0	0	N
MEN1	SLAQPEALK	PROSTATE	527	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	Y	5	16	0	N
MEN1	SLLGLSLAQ	PROSTATE	522	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	0	0	0	N
MEN1	VAARLRCQH	PROSTATE	536	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	0	0	6	N
MEN1	VQCSLSRVR	PROSTATE	553	p.R521fs	c.1561_1561delC	Frame_Shift_Del	5	0.11	22RV1	N	4	0	3	N
MEN1	VSGPPGSLL	PROSTATE	516	p.R521fs	c.1561_1561delC	Frame_Shift_Del	4	0.11	22RV1	N	11	0	0	N
MEN1	ASWDCRWHS	PANCREAS	523	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	6	0.11	T3M4	N	0	0	0	N
MEN1	AVSGPPPEA	PANCREAS	515	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	3	0.11	T3M4	N	0	0	0	N
MEN1	DCRWHSPRP	PANCREAS	526	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	6	0.11	T3M4	N	0	0	0	N
MEN1	EASWDCRWH	PANCREAS	522	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	6	0.11	T3M4	N	0	0	0	N
MEN1	GAVSGPPPE	PANCREAS	514	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	2	0.11	T3M4	N	0	0	0	N
MEN1	GPPPEASWD	PANCREAS	518	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	5	0.11	T3M4	N	0	0	0	N
MEN1	PEASWDCRW	PANCREAS	521	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	6	0.11	T3M4	N	2	0	0	N
MEN1	PPEASWDCR	PANCREAS	520	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	6	0.11	T3M4	N	0	0	0	N
MEN1	PPPEASWDC	PANCREAS	519	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	5	0.11	T3M4	N	0	0	0	N
MEN1	QGAVSGPPP	PANCREAS	513	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	1	0.11	T3M4	N	0	0	0	N
MEN1	SGPPPEASW	PANCREAS	517	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	5	0.11	T3M4	N	3	0	0	N
MEN1	SWDCRWHSP	PANCREAS	524	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	6	0.11	T3M4	N	0	0	0	N
MEN1	VSGPPPEAS	PANCREAS	516	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	4	0.11	T3M4	N	0	0	0	N
MEN1	WDCRWHSPR	PANCREAS	525	p.R521fs	c.1561_1562insC	Frame_Shift_Ins	6	0.11	T3M4	N	2	0	0	N
MEN1	AHLLRLYDG	LARGE_INTESTINE	416	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	0	0	0	Y
MEN1	AINPSINLH	SKIN	247	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	Y	0	12	0	N
MEN1	ALDKDLGTG	CENTRAL_NERVOUS_SYSTEM	504	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	0	0	0	N
MEN1	ANDVTPNLL	ENDOMETRIUM	373	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	Y	6	16	0	N
MEN1	AREGRQRGP	LARGE_INTESTINE	480	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	0	0	0	N
MEN1	ATKINLSAI	SKIN	572	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	Y	5	13	0	N
MEN1	CAINPSINL	SKIN	246	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	Y	14	9	0	N
MEN1	CDRKMEVVF	LUNG	235	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	N	5	0	0	N
MEN1	CFAHLLRLY	LARGE_INTESTINE	414	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	3	0	0	N
MEN1	CLLYDLGHL	LUNG	270	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	15	0	0	N
MEN1	DKDLGTGQG	CENTRAL_NERVOUS_SYSTEM	506	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	0	0	0	N
MEN1	DLGTGQGAV	CENTRAL_NERVOUS_SYSTEM	508	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	3	0	0	N
MEN1	DLHTDLLEL	PROSTATE	253	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	Y	9	10	0	N
MEN1	DLLELLQLQ	PROSTATE	257	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
MEN1	DRKMEVVFM	LUNG	236	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	N	3	0	0	N
MEN1	DVTPNLLKE	ENDOMETRIUM	375	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
MEN1	DYILSFLKR	SKIN	602	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	2	0	0	N
MEN1	DYTLSFLKW	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	602	p.R610W	c.1828C>T	Missense_Mutation	1	0.11	REH	N	3	0	0	N
MEN1	EAREGRQRG	LARGE_INTESTINE	479	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	0	0	0	Y
MEN1	ECFAHLLRL	LARGE_INTESTINE	413	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	11	0	0	N
MEN1	EEAREGRQR	LARGE_INTESTINE	478	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	1	0	0	N
MEN1	EGRQRGPRR	LARGE_INTESTINE	482	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	1	0	0	Y
MEN1	EVANDVTPN	ENDOMETRIUM	371	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
MEN1	EVVFMVCAI	LUNG	240	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	Y	8	12	0	N
MEN1	FAHLLRLYD	LARGE_INTESTINE	415	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	2	0	6	N
MEN1	FEVANDVTP	ENDOMETRIUM	370	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	N	3	0	0	N
MEN1	FFEVANDVT	ENDOMETRIUM	369	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	N	3	0	0	N
MEN1	FLKWQRKGL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	607	p.R610W	c.1828C>T	Missense_Mutation	1	0.11	REH	N	12	0	4	N
MEN1	GEEAREGRQ	LARGE_INTESTINE	477	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	0	0	0	Y
MEN1	GRQRGPRRE	LARGE_INTESTINE	483	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	0	0	0	Y
MEN1	GSHMRCDRK	PROSTATE	230	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
MEN1	GSYMHCDRK	LARGE_INTESTINE	230	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	N	3	0	0	N
MEN1	GTILDSSGV	LARGE_INTESTINE	154	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	N	2	0	0	N
MEN1	GWSPVGTIL	LARGE_INTESTINE	149	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	Y	7	10	0	N
MEN1	HCDRKMEVA	LARGE_INTESTINE	234	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	N	1	0	0	N
MEN1	HLLRLYDGI	LARGE_INTESTINE	417	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	12	0	0	N
MEN1	HMRCDRKME	PROSTATE	232	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
MEN1	HTDLLELLQ	PROSTATE	255	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
MEN1	IDLHTDLLE	PROSTATE	252	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
MEN1	ILDSSGVAF	LARGE_INTESTINE	156	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	N	7	0	0	N
MEN1	ILSFLKRQR	SKIN	604	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	3	0	11	N
MEN1	INLHTDSLE	SKIN	252	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	N	0	0	0	N
MEN1	INLSAIKLQ	SKIN	575	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	N	0	0	18	N
MEN1	INPSINLHT	SKIN	248	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	N	0	0	4	N
MEN1	KDLGTGQGA	CENTRAL_NERVOUS_SYSTEM	507	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	5	0	0	N
MEN1	KGSHMRCDR	PROSTATE	229	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
MEN1	KGSYMHCDR	LARGE_INTESTINE	229	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	N	0	0	0	N
MEN1	KINLSAIKL	SKIN	574	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	Y	9	9	0	N
MEN1	KKPALDKDL	CENTRAL_NERVOUS_SYSTEM	501	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	7	0	0	N
MEN1	KLLCLLYDL	LUNG	267	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	Y	21	13	0	N
MEN1	KMEVVFMVC	LUNG	238	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	N	3	0	0	N
MEN1	KPALDKDLG	CENTRAL_NERVOUS_SYSTEM	502	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	1	0	0	N
MEN1	KVSTPSDYI	SKIN	596	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	5	0	0	N
MEN1	LCLLYDLGH	LUNG	269	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	0	0	0	N
MEN1	LDKDLGTGQ	CENTRAL_NERVOUS_SYSTEM	505	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	0	0	0	N
MEN1	LHTDLLELL	PROSTATE	254	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	6	0	6	N
MEN1	LKGSHMRCD	PROSTATE	228	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
MEN1	LKGSYMHCD	LARGE_INTESTINE	228	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	N	0	0	0	N
MEN1	LLCLLYDLG	LUNG	268	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	0	0	0	N
MEN1	LLELLQLQQ	PROSTATE	258	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	1	0	5	N
MEN1	LLRLYDGIC	LARGE_INTESTINE	418	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	2	0	0	N
MEN1	LLVATKINL	SKIN	569	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	Y	13	12	12	N
MEN1	LQLQQKLLC	LUNG	262	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	4	0	30	Y
MEN1	LQQKLLCLL	LUNG	264	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	17	0	4	Y
MEN1	LRLYDGICK	LARGE_INTESTINE	419	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	2	0	19	N
MEN1	LSAIKLQLT	SKIN	577	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	N	1	0	0	N
MEN1	LSFLKWQRK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	605	p.R610W	c.1828C>T	Missense_Mutation	1	0.11	REH	N	3	0	0	N
MEN1	LVATKINLS	SKIN	570	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	N	0	0	22	N
MEN1	LYDGICKWE	LARGE_INTESTINE	421	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	N	0	0	0	N
MEN1	LYLKGSHMR	PROSTATE	226	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	2	0	13	N
MEN1	LYLKGSYMH	LARGE_INTESTINE	226	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	N	0	0	13	N
MEN1	MEVVFMVCA	LUNG	239	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	N	8	0	0	N
MEN1	MHCDRKMEV	LARGE_INTESTINE	233	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	Y	3	9	8	N
MEN1	NDVTPNLLK	ENDOMETRIUM	374	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	N	1	0	0	N
MEN1	NLHTDSLEL	SKIN	253	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	Y	11	9	0	N
MEN1	NLSAIKLQL	SKIN	576	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	Y	11	9	0	N
MEN1	NPSINLHTD	SKIN	249	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	N	1	0	0	N
MEN1	PALDKDLGT	CENTRAL_NERVOUS_SYSTEM	503	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	0	0	0	N
MEN1	PKKPALDKD	CENTRAL_NERVOUS_SYSTEM	500	p.G508D	c.1523G>A	Missense_Mutation	1	0.11	ONS76	N	0	0	0	N
MEN1	PSDYILSFL	SKIN	600	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	0	0	0	N
MEN1	PSIDLHTDL	PROSTATE	250	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
MEN1	PSINLHTDS	SKIN	250	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	N	0	0	0	N
MEN1	PVGTILDSS	LARGE_INTESTINE	152	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	N	0	0	0	N
MEN1	QKLLCLLYD	LUNG	266	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	0	0	0	N
MEN1	QLQQKLLCL	LUNG	263	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	14	0	0	N
MEN1	QQKLLCLLY	LUNG	265	p.W270C	c.810G>T	Missense_Mutation	1	0.11	NCIH1930	N	6	0	0	Y
MEN1	QRGPRRESK	LARGE_INTESTINE	485	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	3	0	0	N
MEN1	RCDRKMEVV	LUNG	234	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	N	4	0	0	N
MEN1	REGRQRGPR	LARGE_INTESTINE	481	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	2	0	0	Y
MEN1	RKMEVVFMV	LUNG	237	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	Y	6	13	0	N
MEN1	RLYDGICKW	LARGE_INTESTINE	420	p.F421L	c.1261T>C	Missense_Mutation	1	0.11	SNUC5	Y	9	12	0	N
MEN1	RQRGPRRES	LARGE_INTESTINE	484	p.R485Q	c.1454G>A	Missense_Mutation	1	0.11	LOVO	N	1	0	0	N
MEN1	SDYILSFLK	SKIN	601	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	1	0	0	N
MEN1	SFLKWQRKG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	606	p.R610W	c.1828C>T	Missense_Mutation	1	0.11	REH	N	0	0	0	N
MEN1	SHMRCDRKM	PROSTATE	231	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	2	0	0	N
MEN1	SIDLHTDLL	PROSTATE	251	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	5	0	0	N
MEN1	SINLHTDSL	SKIN	251	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	N	5	0	0	N
MEN1	SPVGTILDS	LARGE_INTESTINE	151	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	N	4	0	0	N
MEN1	STPSDYILS	SKIN	598	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	2	0	0	N
MEN1	SWLYLKGSH	PROSTATE	224	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
MEN1	SYMHCDRKM	LARGE_INTESTINE	231	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	N	3	0	0	N
MEN1	TDLLELLQL	PROSTATE	256	p.S258L	c.773C>T	Missense_Mutation	1	0.11	22RV1	N	7	0	0	N
MEN1	TGWSPVGTI	LARGE_INTESTINE	148	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	Y	10	11	0	N
MEN1	TILDSSGVA	LARGE_INTESTINE	155	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	N	1	0	0	N
MEN1	TKINLSAIK	SKIN	573	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	N	1	0	0	N
MEN1	TLSFLKWQR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	604	p.R610W	c.1828C>T	Missense_Mutation	1	0.11	REH	Y	6	11	0	N
MEN1	TPNLLKEAA	ENDOMETRIUM	377	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	N	9	0	0	N
MEN1	TPSDYILSF	SKIN	599	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	Y	11	9	0	N
MEN1	VANDVTPNL	ENDOMETRIUM	372	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	Y	16	11	4	N
MEN1	VATKINLSA	SKIN	571	p.S577L	c.1730C>T	Missense_Mutation	1	0.11	SKMEL3	N	5	0	1	N
MEN1	VCAINPSIN	SKIN	245	p.D253N	c.757G>A	Missense_Mutation	1	0.11	SKMEL1	N	0	0	0	N
MEN1	VFMVCAINP	LUNG	242	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	N	0	0	8	N
MEN1	VGTILDSSG	LARGE_INTESTINE	153	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	N	0	0	0	N
MEN1	VSTPSDYIL	SKIN	597	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	9	0	0	N
MEN1	VTPNLLKEA	ENDOMETRIUM	376	p.I377T	c.1130T>C	Missense_Mutation	1	0.11	HEC59	N	2	0	0	N
MEN1	VVFMVCAIN	LUNG	241	p.A242V	c.725C>T	Missense_Mutation	1	0.11	NCIH209	N	0	0	35	N
MEN1	WLYLKGSHM	PROSTATE	225	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	Y	13	10	7	N
MEN1	WSPVGTILD	LARGE_INTESTINE	150	p.K156I	c.467A>T	Missense_Mutation	1	0.11	SNUC5	N	2	0	3	N
MEN1	YILSFLKRQ	SKIN	603	p.T604I	c.1811C>T	Missense_Mutation	1	0.11	CHL1	N	2	0	14	N
MEN1	YLKGSHMRC	PROSTATE	227	p.Y232H	c.694T>C	Missense_Mutation	1	0.11	22RV1	N	4	0	2	N
MEN1	YLKGSYMHC	LARGE_INTESTINE	227	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	Y	4	9	0	N
MEN1	YMHCDRKME	LARGE_INTESTINE	232	p.R234H	c.701G>A	Missense_Mutation	1	0.11	LS180	N	3	0	4	N
MEN1	YTLSFLKWQ	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	603	p.R610W	c.1828C>T	Missense_Mutation	1	0.11	REH	N	3	0	0	N
MEN1	DVHLTLSED	ENDOMETRIUM	177	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	N	0	0	0	N
MEN1	DVHLTLSED	OVARY	177	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	N	0	0	0	N
MEN1	EERRGQTVN	SKIN	209	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	3	0	0	N
MEN1	EERRGQTVN	SKIN	209	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	3	0	0	N
MEN1	ERRGQTVNA	SKIN	210	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	1	0	0	N
MEN1	ERRGQTVNA	SKIN	210	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	1	0	0	N
MEN1	GKGNEERRG	SKIN	205	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	0	0	0	N
MEN1	GKGNEERRG	SKIN	205	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	0	0	0	N
MEN1	GLRDVHLTL	ENDOMETRIUM	174	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	Y	12	12	0	N
MEN1	GLRDVHLTL	OVARY	174	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	Y	12	12	0	N
MEN1	GNEERRGQT	SKIN	207	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	0	0	0	N
MEN1	GNEERRGQT	SKIN	207	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	0	0	0	N
MEN1	HGKGNEERR	SKIN	204	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	1	0	0	N
MEN1	HGKGNEERR	SKIN	204	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	1	0	0	N
MEN1	HLTLSEDHA	ENDOMETRIUM	179	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	N	1	0	0	N
MEN1	HLTLSEDHA	OVARY	179	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	N	1	0	0	N
MEN1	KGNEERRGQ	SKIN	206	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	0	0	0	N
MEN1	KGNEERRGQ	SKIN	206	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	0	0	0	N
MEN1	LGLRDVHLT	ENDOMETRIUM	173	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	N	1	0	14	N
MEN1	LGLRDVHLT	OVARY	173	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	N	1	0	14	N
MEN1	LRDVHLTLS	ENDOMETRIUM	175	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	N	3	0	0	N
MEN1	LRDVHLTLS	OVARY	175	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	N	3	0	0	N
MEN1	LTLSEDHAW	ENDOMETRIUM	180	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	N	3	0	0	N
MEN1	LTLSEDHAW	OVARY	180	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	N	3	0	0	N
MEN1	NEERRGQTV	SKIN	208	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	Y	6	9	0	N
MEN1	NEERRGQTV	SKIN	208	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	Y	6	9	0	N
MEN1	RDVHLTLSE	ENDOMETRIUM	176	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	N	0	0	0	N
MEN1	RDVHLTLSE	OVARY	176	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	N	0	0	0	N
MEN1	TLSEDHAWV	ENDOMETRIUM	181	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	Y	5	10	0	N
MEN1	TLSEDHAWV	OVARY	181	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	Y	5	10	0	N
MEN1	TWHGKGNEE	SKIN	202	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	0	0	0	N
MEN1	TWHGKGNEE	SKIN	202	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	0	0	0	N
MEN1	VHLTLSEDH	ENDOMETRIUM	178	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO684	N	0	0	2	N
MEN1	VHLTLSEDH	OVARY	178	p.A181T	c.541G>A	Missense_Mutation	1	0.22	COLO704	N	0	0	2	N
MEN1	WHGKGNEER	SKIN	203	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR37	N	2	0	0	N
MEN1	WHGKGNEER	SKIN	203	p.D210E	c.630C>A	Missense_Mutation	1	0.22	IGR39	N	2	0	0	N