Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
HSP90B1KSLPSKPKLHAEMATOPOIETIC_AND_LYMPHOID_TISSUE73p.R70fsc.208_211delAGAGFrame_Shift_Del60.11KMS11N1700N
HSP90B1LPSKPKLTEHAEMATOPOIETIC_AND_LYMPHOID_TISSUE75p.R70fsc.208_211delAGAGFrame_Shift_Del60.11KMS11N205N
HSP90B1NLVKNIHSSLARGE_INTESTINE266p.K269fsc.805_805delAFrame_Shift_Del50.11SNU175N200Y
HSP90B1RKSLPSKPKHAEMATOPOIETIC_AND_LYMPHOID_TISSUE72p.R70fsc.208_211delAGAGFrame_Shift_Del50.11KMS11N200N
HSP90B1RSRKSLPSKHAEMATOPOIETIC_AND_LYMPHOID_TISSUE70p.R70fsc.208_211delAGAGFrame_Shift_Del50.11KMS11N300N
HSP90B1SLPSKPKLTHAEMATOPOIETIC_AND_LYMPHOID_TISSUE74p.R70fsc.208_211delAGAGFrame_Shift_Del60.11KMS11N300Y