Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
HSP90B1	ASQIRELRS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	63	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	1	0.11	KMS11	N	0	0	0	N
HSP90B1	DTIKNLVKN	LARGE_INTESTINE	262	p.K269fs	c.805_805delA	Frame_Shift_Del	1	0.11	SNU175	N	1	0	0	N
HSP90B1	ELRSRKSLP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	68	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	4	0.11	KMS11	N	1	0	0	N
HSP90B1	IKNLVKNIH	LARGE_INTESTINE	264	p.K269fs	c.805_805delA	Frame_Shift_Del	3	0.11	SNU175	N	1	0	27	N
HSP90B1	IRELRSRKS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	66	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	4	0.11	KMS11	N	2	0	23	N
HSP90B1	KNLVKNIHS	LARGE_INTESTINE	265	p.K269fs	c.805_805delA	Frame_Shift_Del	4	0.11	SNU175	N	0	0	0	N
HSP90B1	KSLPSKPKL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	73	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	6	0.11	KMS11	N	17	0	0	N
HSP90B1	LPSKPKLTE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	75	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	6	0.11	KMS11	N	2	0	5	N
HSP90B1	LRSRKSLPS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	69	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	4	0.11	KMS11	N	2	0	39	N
HSP90B1	NLVKNIHSS	LARGE_INTESTINE	266	p.K269fs	c.805_805delA	Frame_Shift_Del	5	0.11	SNU175	N	2	0	0	Y
HSP90B1	QIRELRSRK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	65	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	3	0.11	KMS11	Y	2	15	0	N
HSP90B1	RELRSRKSL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	67	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	4	0.11	KMS11	N	10	0	0	N
HSP90B1	RKSLPSKPK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	72	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	5	0.11	KMS11	N	2	0	0	N
HSP90B1	RSRKSLPSK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	70	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	5	0.11	KMS11	N	3	0	0	N
HSP90B1	SLPSKPKLT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	74	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	6	0.11	KMS11	N	3	0	0	Y
HSP90B1	SQIRELRSR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	64	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	2	0.11	KMS11	N	5	0	0	N
HSP90B1	SRKSLPSKP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	71	p.R70fs	c.208_211delAGAG	Frame_Shift_Del	4	0.11	KMS11	N	1	0	0	N
HSP90B1	TIKNLVKNI	LARGE_INTESTINE	263	p.K269fs	c.805_805delA	Frame_Shift_Del	2	0.11	SNU175	Y	3	11	0	N
HSP90B1	AGSIRKEAE	LARGE_INTESTINE	542	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
HSP90B1	AIQLDGLNS	LARGE_INTESTINE	55	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
HSP90B1	AITLVLKEE	ENDOMETRIUM	246	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	N	0	0	0	N
HSP90B1	AKVEEEPKE	ENDOMETRIUM	753	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
HSP90B1	AKVEEQPEE	LUNG	753	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	ALPKFDGKR	LARGE_INTESTINE	579	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	6	0	0	N
HSP90B1	AQEDGQSIS	URINARY_TRACT	181	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	0	0	0	N
HSP90B1	ATLRSGYLS	BREAST	721	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	0	0	0	N
HSP90B1	AYQTGKDNS	CENTRAL_NERVOUS_SYSTEM	666	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	N	2	0	0	N
HSP90B1	CASQKKTFE	ENDOMETRIUM	678	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	0	0	0	N
HSP90B1	CIQALPKFD	LARGE_INTESTINE	576	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	0	0	0	N
HSP90B1	CRVFITDDF	LUNG	414	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	N	4	0	0	N
HSP90B1	DAKVEEEPK	ENDOMETRIUM	752	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	1	0	0	N
HSP90B1	DAKVEEQPE	LUNG	752	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	DEYGFKKSD	SKIN	399	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	1	0	0	N
HSP90B1	DGLNSSQIR	LARGE_INTESTINE	59	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	1	0	0	N
HSP90B1	DGPMAYIHF	UPPER_AERODIGESTIVE_TRACT	367	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	Y	7	9	0	N
HSP90B1	DGQSISELI	URINARY_TRACT	184	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	7	0	0	N
HSP90B1	DISTNYCAS	ENDOMETRIUM	672	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	2	0	0	N
HSP90B1	DKIYFIAGS	BREAST	536	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	2	0	0	N
HSP90B1	DMLQRIKED	ENDOMETRIUM	696	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
HSP90B1	DNSTNYYAS	CENTRAL_NERVOUS_SYSTEM	672	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	N	1	0	0	N
HSP90B1	DPDAKVEEQ	LUNG	750	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	DYIKLYVCR	LUNG	407	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	Y	2	10	0	N
HSP90B1	EAQEDGQSI	URINARY_TRACT	180	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	5	0	0	N
HSP90B1	EDGQSISEL	URINARY_TRACT	183	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	6	0	0	N
HSP90B1	EEEPKEEPE	ENDOMETRIUM	756	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
HSP90B1	EEPKEEPEE	ENDOMETRIUM	757	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
HSP90B1	EEQPEEEPE	LUNG	756	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	EKQDKIYFI	BREAST	533	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	4	0	0	N
HSP90B1	ENHSNRTRL	ENDOMETRIUM	498	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	Y	6	19	0	Y
HSP90B1	EPKEEPEET	ENDOMETRIUM	758	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	4	0	0	N
HSP90B1	EQPEEEPEE	LUNG	757	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	ESDGPMAYI	UPPER_AERODIGESTIVE_TRACT	365	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	Y	6	13	0	N
HSP90B1	ESLCALVAS	ENDOMETRIUM	642	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	1	0	0	N
HSP90B1	EYCIQALPK	LARGE_INTESTINE	574	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	2	0	0	N
HSP90B1	EYGFKKSDY	SKIN	400	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	2	0	0	N
HSP90B1	FDEYGFKKS	SKIN	398	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	3	0	0	N
HSP90B1	FIAGSSRKE	BREAST	540	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	1	0	0	N
HSP90B1	FKKSDYIKL	SKIN	403	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	Y	7	12	2	N
HSP90B1	FMAGSIRKE	LARGE_INTESTINE	540	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	1	0	0	N
HSP90B1	FSKESDGPM	UPPER_AERODIGESTIVE_TRACT	362	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	N	7	0	0	N
HSP90B1	GFKKSDYIK	SKIN	402	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	2	0	0	N
HSP90B1	GKDISTNYC	ENDOMETRIUM	670	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	1	0	0	Y
HSP90B1	GKDNSTNYY	CENTRAL_NERVOUS_SYSTEM	670	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	N	3	0	0	N
HSP90B1	GLFDEYGFK	SKIN	396	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	7	0	0	N
HSP90B1	GLNSSQIRE	LARGE_INTESTINE	60	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
HSP90B1	GMTITLVLK	ENDOMETRIUM	244	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	0	N
HSP90B1	GNTLGRGMT	ENDOMETRIUM	238	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
HSP90B1	GNTLGRGTA	ENDOMETRIUM	238	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	N	1	0	0	N
HSP90B1	GPMAYIHFT	UPPER_AERODIGESTIVE_TRACT	368	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	N	5	0	0	N
HSP90B1	GQSISELIG	URINARY_TRACT	185	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	0	0	0	N
HSP90B1	GRGMTITLV	ENDOMETRIUM	242	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	Y	4	10	0	N
HSP90B1	GRGTAITLV	ENDOMETRIUM	242	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	N	4	0	0	N
HSP90B1	GSIRKEAES	LARGE_INTESTINE	543	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
HSP90B1	GTAITLVLK	ENDOMETRIUM	244	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	Y	3	13	0	N
HSP90B1	GVIENHSNR	ENDOMETRIUM	495	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	Y	6	10	0	N
HSP90B1	GYLSPDTKA	BREAST	726	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	3	0	0	N
HSP90B1	HPLIRDMLQ	ENDOMETRIUM	691	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	1	0	0	N
HSP90B1	IAGSSRKEA	BREAST	541	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	4	0	0	N
HSP90B1	IENHSNRTR	ENDOMETRIUM	497	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	Y	0	10	6	Y
HSP90B1	IKLGVIENH	ENDOMETRIUM	492	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	N	1	0	6	N
HSP90B1	IKLYVCRVF	LUNG	409	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	N	5	0	21	N
HSP90B1	IQALPKFDG	LARGE_INTESTINE	577	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	0	0	22	N
HSP90B1	IQLDGLNSS	LARGE_INTESTINE	56	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	1	0	14	N
HSP90B1	IRDMLQRIK	ENDOMETRIUM	694	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	Y	2	10	7	N
HSP90B1	IRKEAESSP	LARGE_INTESTINE	545	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	1	0	0	N
HSP90B1	ISELIGQFG	URINARY_TRACT	188	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	1	0	0	N
HSP90B1	ISTNYCASQ	ENDOMETRIUM	673	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	0	0	0	N
HSP90B1	IYFIAGSSR	BREAST	538	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	3	0	3	N
HSP90B1	IYFMAGSIR	LARGE_INTESTINE	538	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	3	0	3	N
HSP90B1	KDISTNYCA	ENDOMETRIUM	671	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	6	0	0	N
HSP90B1	KDNSTNYYA	CENTRAL_NERVOUS_SYSTEM	671	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	Y	5	10	0	N
HSP90B1	KEEPEETAE	ENDOMETRIUM	760	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
HSP90B1	KESDGPMAY	UPPER_AERODIGESTIVE_TRACT	364	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	Y	8	9	0	N
HSP90B1	KFDGKRFQN	LARGE_INTESTINE	582	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	0	0	0	N
HSP90B1	KIYFIAGSS	BREAST	537	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	0	0	0	N
HSP90B1	KIYFMAGSI	LARGE_INTESTINE	537	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	10	0	0	N
HSP90B1	KLGVIENHS	ENDOMETRIUM	493	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
HSP90B1	KLYVCRVFI	LUNG	410	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	Y	15	17	0	N
HSP90B1	KQDKIYFIA	BREAST	534	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	6	0	0	N
HSP90B1	KSFSKESDG	UPPER_AERODIGESTIVE_TRACT	360	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	N	0	0	0	Y
HSP90B1	KVEEEPKEE	ENDOMETRIUM	754	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
HSP90B1	KVEEQPEEE	LUNG	754	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	LCALVASQY	ENDOMETRIUM	644	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	0	N
HSP90B1	LDGLNSSQI	LARGE_INTESTINE	58	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	4	0	0	N
HSP90B1	LFDEYGFKK	SKIN	397	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	2	0	0	N
HSP90B1	LGRGMTITL	ENDOMETRIUM	241	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	N	11	0	4	N
HSP90B1	LGRGTAITL	ENDOMETRIUM	241	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	N	11	0	5	N
HSP90B1	LGVIENHSN	ENDOMETRIUM	494	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	N	0	0	2	N
HSP90B1	LIRDMLQRI	ENDOMETRIUM	693	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	7	0	8	N
HSP90B1	LNSSQIREL	LARGE_INTESTINE	61	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	5	0	2	N
HSP90B1	LPKFDGKRF	LARGE_INTESTINE	580	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	10	0	0	N
HSP90B1	LQRIKEDED	ENDOMETRIUM	698	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	0	0	0	Y
HSP90B1	LRSGYLSPD	BREAST	723	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	1	0	0	N
HSP90B1	LSPDTKAYG	BREAST	728	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	0	0	7	N
HSP90B1	LTESLCALV	ENDOMETRIUM	640	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	0	N
HSP90B1	LYVCRVFIT	LUNG	411	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	Y	3	10	7	N
HSP90B1	MAGSIRKEA	LARGE_INTESTINE	541	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	5	0	0	N
HSP90B1	MLQRIKEDE	ENDOMETRIUM	697	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	0	0	4	N
HSP90B1	MTITLVLKE	ENDOMETRIUM	245	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	9	N
HSP90B1	NHSNRTRLA	ENDOMETRIUM	499	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	N	1	0	0	N
HSP90B1	NIKLGVIEN	ENDOMETRIUM	491	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
HSP90B1	NSSQIRELR	LARGE_INTESTINE	62	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	3	0	0	N
HSP90B1	NSTNYYASQ	CENTRAL_NERVOUS_SYSTEM	673	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	N	0	0	0	Y
HSP90B1	NTLGRGMTI	ENDOMETRIUM	239	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	Y	7	13	0	N
HSP90B1	NTLGRGTAI	ENDOMETRIUM	239	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	Y	7	13	0	N
HSP90B1	NYCASQKKT	ENDOMETRIUM	676	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	2	0	0	N
HSP90B1	PDAKVEEQP	LUNG	751	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	PKEEPEETA	ENDOMETRIUM	759	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
HSP90B1	PKFDGKRFQ	LARGE_INTESTINE	581	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	0	0	0	N
HSP90B1	PLIRDMLQR	ENDOMETRIUM	692	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	2	0	0	N
HSP90B1	QALPKFDGK	LARGE_INTESTINE	578	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	4	0	0	N
HSP90B1	QAYQTGKDN	CENTRAL_NERVOUS_SYSTEM	665	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	N	3	0	0	N
HSP90B1	QDKIYFIAG	BREAST	535	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	0	0	0	N
HSP90B1	QEDGQSISE	URINARY_TRACT	182	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	0	0	0	N
HSP90B1	QLDGLNSSQ	LARGE_INTESTINE	57	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
HSP90B1	QPEEEPEET	LUNG	758	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	2	0	0	N
HSP90B1	QRIKEDEDD	ENDOMETRIUM	699	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	1	0	0	N
HSP90B1	QRLTESLCA	ENDOMETRIUM	638	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	2	0	0	N
HSP90B1	QSISELIGQ	URINARY_TRACT	186	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	0	0	0	N
HSP90B1	QTGKDNSTN	CENTRAL_NERVOUS_SYSTEM	668	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	N	1	0	0	N
HSP90B1	RDMLQRIKE	ENDOMETRIUM	695	p.R699Q	c.2096G>A	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
HSP90B1	RGLFDEYGF	SKIN	395	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	7	0	0	Y
HSP90B1	RGMTITLVL	ENDOMETRIUM	243	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	N	20	0	0	N
HSP90B1	RGNTLGRGM	ENDOMETRIUM	237	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	0	Y
HSP90B1	RGTAITLVL	ENDOMETRIUM	243	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	N	14	0	0	N
HSP90B1	RLTESLCAL	ENDOMETRIUM	639	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	Y	16	11	0	N
HSP90B1	RSGYLSPDT	BREAST	724	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	1	0	0	N
HSP90B1	SDGPMAYIH	UPPER_AERODIGESTIVE_TRACT	366	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	N	0	0	0	N
HSP90B1	SDYIKLYVC	LUNG	406	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	N	4	0	0	N
HSP90B1	SFSKESDGP	UPPER_AERODIGESTIVE_TRACT	361	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	N	0	0	0	N
HSP90B1	SGYLSPDTK	BREAST	725	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	1	0	0	N
HSP90B1	SIRKEAESS	LARGE_INTESTINE	544	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
HSP90B1	SISELIGQF	URINARY_TRACT	187	p.T188I	c.563C>T	Missense_Mutation	1	0.11	ACCS	N	6	0	0	N
HSP90B1	SKESDGPMA	UPPER_AERODIGESTIVE_TRACT	363	p.D368G	c.1103A>G	Missense_Mutation	1	0.11	CAL33	N	1	0	0	N
HSP90B1	SLCALVASQ	ENDOMETRIUM	643	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
HSP90B1	SPDTKAYGD	BREAST	729	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	0	0	0	N
HSP90B1	SQRLTESLC	ENDOMETRIUM	637	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	2	0	0	N
HSP90B1	SSQIRELRE	LARGE_INTESTINE	63	p.A63S	c.187G>T	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
HSP90B1	STNYCASQK	ENDOMETRIUM	674	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	Y	1	12	0	Y
HSP90B1	TAITLVLKE	ENDOMETRIUM	245	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	N	0	0	0	N
HSP90B1	TESLCALVA	ENDOMETRIUM	641	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	0	N
HSP90B1	TGKDNSTNY	CENTRAL_NERVOUS_SYSTEM	669	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	Y	5	12	0	N
HSP90B1	TLGRGMTIT	ENDOMETRIUM	240	p.T245M	c.734C>T	Missense_Mutation	1	0.11	HEC6	N	3	0	0	N
HSP90B1	TLGRGTAIT	ENDOMETRIUM	240	p.T246A	c.736A>G	Missense_Mutation	1	0.11	JHUEM2	N	1	0	0	N
HSP90B1	TLRSGYLSP	BREAST	722	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	0	0	0	N
HSP90B1	TNYCASQKK	ENDOMETRIUM	675	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	1	0	0	N
HSP90B1	VCRVFITDD	LUNG	413	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	N	0	0	0	N
HSP90B1	VEEEPKEEP	ENDOMETRIUM	755	p.E760K	c.2278G>A	Missense_Mutation	1	0.11	JHUEM7	N	0	0	0	N
HSP90B1	VEEQPEEEP	LUNG	755	p.E758Q	c.2272G>C	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
HSP90B1	VIENHSNRT	ENDOMETRIUM	496	p.D499N	c.1495G>A	Missense_Mutation	1	0.11	HEC59	N	1	0	0	N
HSP90B1	VSQRLTESL	ENDOMETRIUM	636	p.P644L	c.1931C>T	Missense_Mutation	1	0.11	HEC6	N	13	0	0	N
HSP90B1	YCASQKKTF	ENDOMETRIUM	677	p.Y678C	c.2033A>G	Missense_Mutation	1	0.11	EN	N	6	0	0	N
HSP90B1	YCIQALPKF	LARGE_INTESTINE	575	p.E582K	c.1744G>A	Missense_Mutation	1	0.11	SNU81	N	7	0	4	N
HSP90B1	YFIAGSSRK	BREAST	539	p.M541I	c.1623G>A	Missense_Mutation	1	0.11	BT474	N	3	0	12	N
HSP90B1	YFMAGSIRK	LARGE_INTESTINE	539	p.S545I	c.1634G>T	Missense_Mutation	1	0.11	HRT18	N	4	0	21	N
HSP90B1	YGFKKSDYI	SKIN	401	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HS936T	N	10	0	1	N
HSP90B1	YIKLYVCRV	LUNG	408	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	Y	7	9	19	N
HSP90B1	YLSPDTKAY	BREAST	727	p.L729S	c.2186T>C	Missense_Mutation	1	0.11	UACC812	N	7	0	0	N
HSP90B1	YQTGKDNST	CENTRAL_NERVOUS_SYSTEM	667	p.I673N	c.2018T>A	Missense_Mutation	1	0.11	A172	N	5	0	0	N
HSP90B1	YVCRVFITD	LUNG	412	p.R414C	c.1240C>T	Missense_Mutation	1	0.11	NCIH1781	N	2	0	2	N