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5011 details
Primary information
CancerPPD ID5011
PMID24661024
YEAR2014
SEQUENCEGIGAVLKVLTTGLPALISWIKRKRQQ
LENGTH26
NAMEMelittin
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
L/D/MixL
Non-NaturalNone
NATUREAntimicrobial
ACTIVITY102.9 ± 4.1% cell growth inhibition at 1 µM
SOURCEMain component of honey bee venom
Cancer TypeSkin Cancer
ASSAYCell Viability assay
Patent IDNone
TissueSkin
CELL LINESCC25
TEST TIME24-h
Secondary information
STRUCTURE
Predicted Structure
DSSP statesCCTTHHHHSSSSCTTHHHHHHHHHCC
SMILES[NH3]CC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N1[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCC(=O)N)CCC(=O)N)CCCNC(=[NH2])N)CCCC[NH3])CCCNC(=[NH2])N)CCCC[NH3])[C@H](CC)C)Cc2c[nH]c3c2cccc3)CO)[C@H](CC)C)CC(C)C)C)CCC1)CC(C)C)[C@H](O)C)[C@H](O)C)CC(C)C)C(C)C)CCCC[NH3])CC(C)C)C(C)C)C)[C@H](CC)C
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1bh1ANANANANANA20271NA