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5002 details
Primary information
CancerPPD ID5002
PMID24587350
YEAR2014
SEQUENCELLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
LENGTH37
NAMELL 37
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
L/D/MixL
Non-NaturalNone
NATUREAntimicrobial
ACTIVITYLC50= 21 at 100 µM
SOURCEAlso known human cathelicidin
Cancer TypeBreast Cancer
ASSAYMTT/MTS assay
Patent IDNone
TissueBreast
CELL LINEMCF-7
TEST TIME72-h
Secondary information
STRUCTURE
Predicted Structure
DSSP statesCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSSCCC
SMILES[NH3][C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)CCC(=O)O)[C@H](O)C)CCCNC(=[NH2])N)CCC1)C(C)C)CC(C)C)CC(=O)N)CCCNC(=[NH2])N)CC(C)C)Cc1ccccc1)CC(=O)O)CCCC[NH3])[C@H](CC)C)CCCNC(=[NH2])N)CCC(=O)N)C(C)C)[C@H](CC)C)CCCNC(=[NH2])N)CCCC[NH3])Cc1ccccc1)CCC(=O)O)CCCC[NH3])[C@H](CC)C)CCCC[NH3])CCC(=O)O)CCCC[NH3])CO)CCCC[NH3])CCCNC(=[NH2])N)Cc1ccccc1)Cc1ccccc1)CC(=O)O)CC(C)C)CC(C)C
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2k6oANANA>sp_P49913_CAMP_HUMANCathelicidinantimicrobialpeNA>tr_J3KNB4_J3KNB4_HUMANCathelicidinantimicrobialpeptideOS=HomosapiensGN=CAMPPE=4SV=1NANA