Detail description

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4675 details
Primary information
CancerPPD ID4675
PMID9492845
YEAR1998
SEQUENCE2-[[2-(dimethylamino)-3-methylbutanoyl]amino]-N-
[3-methoxy-1-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-phenyl-
1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-
yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide
LENGTHNot Available
NAMEDolastatin 10
C-ter ModificationNot Available
N-ter ModificationNot Available
Linear/CyclicNot Available
L/D/MixNot Available
Non-NaturalNot Available
NATUREAntineoplastic
ACTIVITYIC50=0.5 nM
SOURCEDolabella auricularia
Cancer TypeProstate cancer
ASSAYTUNEL assay
Patent IDNone
TissueProstate
CELL LINEDU-145
TEST TIME96-h
Secondary information
STRUCTURE
Predicted Structure
DSSP statesNA
SMILESNA
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NANANANANANANANA