Primary information |
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CancerPPD ID | 4597 |
PMID | 21403917 |
YEAR | 2011 |
SEQUENCE | RGGRLCYCRRRFCVCVGR |
LENGTH | 18 |
NAME | Protegrin 1 |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
L/D/Mix | L |
Non-Natural | None |
NATURE | Antimicrobial |
ACTIVITY | IC50 =30-40 µg/ml |
SOURCE | alpha helical peptide without cysteines |
Cancer Type | Lymphoma Cancer |
ASSAY | MTT/MTS assay |
Patent ID | None |
Tissue | Blood |
CELL LINE | U-942 |
TEST TIME | Not Available |
Secondary information |
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STRUCTURE | |
DSSP states | CCSEEEEEETTEEEEEEC |
SMILES | [NH3][C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]1C(=O)N[C@H](C(=O)N[C@@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N)CCCNC(=[NH2])N)C(C)C)CSSC1)C(C)C)CSSC2)Cc1ccccc1)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CCCNC(=[NH2])N)Cc1ccc(cc1)O)CC(C)C)CCCNC(=[NH2])N)CCCNC(=[NH2])N |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA | NA | NA | NA | NA | NA | NA | NA |
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