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3594 details
Primary information
CancerPPD ID3594
PMID22100226
YEAR2012
SEQUENCEGFKMALKLLKKVL
LENGTH13
NAMEMAC1/10
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
L/D/MixL
Non-NaturalNone
NATUREAntimicrobial and Antifungal
ACTIVITYIC50 = 15±6 µM
SOURCEMacropins and their analogs
Cancer TypeCervical Cancer
ASSAYMTT/MTS assay
Patent IDNone
TissueCervix
CELL LINEHeLa
TEST TIME48-h
Secondary information
STRUCTURE
Predicted Structure
DSSP statesCHHHHHHHHTTTC
SMILESNCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
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