| Primary information |
|---|
| CancerPPD ID | 2918 |
| PMID | 21849092 |
| YEAR | 2011 |
| SEQUENCE | THRPPMWSPVWPGGGKLlLKlLkkLLKlLKKK |
| LENGTH | 32 |
| NAME | Transferrin receptor (TfR)-lytic hybrid peptide |
| C-ter Modification | Free |
| N-ter Modification | Free |
| Linear/Cyclic | Linear |
| L/D/Mix | Mix |
| Non-Natural | None |
| NATURE | Anticancer |
| ACTIVITY | IC50= 9.3 µM |
| SOURCE | Transferrin receptor (TfR) |
| Cancer Type | Breast Cancer |
| ASSAY | WST-1 assay |
| Patent ID | None |
| Tissue | Breast |
| CELL LINE | ZR75-1 |
| TEST TIME | 72-h |
| Secondary information |
|---|
| STRUCTURE | |
| DSSP states | CCSSSSSCSSCCCTHHHHHHHHHHHHHHHHHC |
| SMILES | N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O |
| External Links |
|---|
| PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
| NA | NA | NA | NA | >tr_Q95VE8_Q95VE8_MUSDOCecropinOS=MuscadomesticaGN=Cep1PE=3SV=1 | NA | NA | NA |
|