Primary information |
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CancerPPD ID | 1116 |
PMID | 8319212 |
YEAR | 1993 |
SEQUENCE | GIGKFLHSAKKFGKAFVGEIMNS |
LENGTH | 23 |
NAME | Magainin 2 |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
L/D/Mix | L |
Non-Natural | None |
NATURE | Antibacterial |
ACTIVITY | IC50=110 µM |
SOURCE | African clawed frog Xenopus laevis skin |
Cancer Type | Lung Cancer |
ASSAY | MTT/MTS assay |
Patent ID | None |
Tissue | Lung |
CELL LINE | A-549 |
TEST TIME | 48-h |
Secondary information |
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STRUCTURE | |
DSSP states | CCSSTHHHHTTTGGGTTTTTTTC |
SMILES | [NH3]CC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)CC(=O)N)CCSC)[C@H](CC)C)CCC(=O)O)C(C)C)Cc1ccccc1)C)CCCC[NH3])Cc1ccccc1)CCCC[NH3])CCCC[NH3])C)CO)CC1=CNCN1)CC(C)C)Cc1ccccc1)CCCC[NH3])[C@H](CC)C |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
2lsaA | NA | NA | NA | NA | NA | NA | NA |
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