Primary information |
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CancerPPD ID | 1045 |
PMID | 1319823, 2285300 |
YEAR | 1992 |
SEQUENCE | AIGKFLHSAKKFGKAFVGEIMNS |
LENGTH | 23 |
NAME | Magainin A |
C-ter Modification | Amidation |
N-ter Modification | Beta-alanine |
Linear/Cyclic | Linear |
L/D/Mix | L |
Non-Natural | None |
NATURE | Antibacterial |
ACTIVITY | IC50=9.7 µM |
SOURCE | African clawed frog Xenopus laevis skin |
Cancer Type | Lung Cancer |
ASSAY | MTT/MTS assay |
Patent ID | None |
Tissue | Lung |
CELL LINE | NCI-H841 |
TEST TIME | 24-h |
Secondary information |
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STRUCTURE | |
DSSP states | CCTHHHHHHHHHHHHTTTTHHHHC |
SMILES | NC[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA | NA | NA | NA | NA | NA | NA | NA |
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