| Primary information |
|---|
| sequence ID | Seq_8011 |
| Peptide sequence | SYSTTAVVTNPKE |
| CancerPDF_ID | CancerPDF_ID343, CancerPDF_ID8589, CancerPDF_ID8590, CancerPDF_ID9903, |
| PMID | 19795908,23667664,23667664,21533267 |
| Protein Name | Transthyretin,Transthyretin,Transthyretin,Transthyretin |
| UniprotKB Entry Name | TTHY_HUMAN,TTHY_HUMAN,TTHY_HUMAN,TTHY_HUMAN |
| Fluid | Plasma,Serum,Serum,Serum |
| M/Z | 698.848,1395.69,1409.7,698.82 |
| Charge | 2,1,1,2 |
| Mass (in Da) | NA,1397.53,1411.55,NA |
| fdr | NA,NA,NA,NA |
| Profiling Technique | LC-MS,MALDI-TOF,MALDI-TOF,LC-MS |
| Peptide Identification technique | MALDI-TOF/TOF,FT-ICR MS/MS + nano-HPLC,FT-ICR MS/MS + nano-HPLC,LC/MS/MS |
| Quantification Technique | LC-MRM (multiple reaction monitoring),NA,NA,Multiple Reaction Monitoring |
| Labelled/Label Free | Labelled,Label Free,Label Free,Label Free |
| FDR | less than 7%,NA,NA,1.49 |
| CancerPDF_ID | CancerPDF_ID343, CancerPDF_ID8589, CancerPDF_ID8590, CancerPDF_ID9903, |
| p-Value | NA,NA,NA,NA |
| Software | FlexAnalysis 3.0 and Biotools 3.0 software,MASCOT,MASCOT,MASCOT |
| Length | 13,13,13,13 |
| Cancer Type | Ductal adenocarcinoma of the pancreas (DAP),"Breast cancer, Lung cancer, Rectal cancer","Breast cancer, Lung cancer, Rectal cancer",Lung adenocarcinoma |
| Database | NCBI refseq Protein Database,NA,NA,Swissprot Database (57.4) |
| Modification | NA,NA,Methylation at K-12,NA |
| Number of Patients | "41 normal, 24 patients","Breast Cancer =84, lung cancer= 70, Rectal cancer = 30patients; 500 healthy","Breast Cancer =84, lung cancer= 70, Rectal cancer = 30patients; 500 healthy",62 lung adenocarcinoma and 30 healthy control |
| Regulation | NA,NA,NA,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal" |
| Validation | NA,NA,NA,MRM-based validation of 19 candidates |
| Sensitivity | NA,NA,NA,NA |
| Specificity | NA,NA,NA,NA |
| Accuracy | NA,NA,NA,NA |
| Peptide Atlas | PeptideAtlas |
| IEDB | 439049
|