| Primary information |
|---|
| sequence ID | Seq_7874 |
| Peptide sequence | SVQLTEKRMD |
| CancerPDF_ID | CancerPDF_ID1483, CancerPDF_ID1512, CancerPDF_ID2672, CancerPDF_ID12339, CancerPDF_ID12671, CancerPDF_ID12698, |
| PMID | 21136997,21136997,21136997,26992070,26992070,27058005 |
| Protein Name | Complement C3,Complement C3,Complement C3,Complement C3,Complement C3,Complement C3 |
| UniprotKB Entry Name | CO3_HUMAN,CO3_HUMAN,CO3_HUMAN,CO3_HUMAN,CO3_HUMAN,CO3_HUMAN |
| Fluid | Serum,Serum,Plasma,Serum,Serum,Serum |
| M/Z | 1205.60742,1221.60234,1205.6074,1205.6074,NA,1206.7 |
| Charge | 1,1,1,NA,NA,NA |
| Mass (in Da) | NA,NA,NA,1206.615848,1222.608555,NA |
| fdr | NA,NA,NA,NA,NA,NA |
| Profiling Technique | LC-MS,LC-MS,LC-MS,LC-MS,LC-MS,MALDI-TOF |
| Peptide Identification technique | LC-MS-MS/MS,LC-MS-MS/MS,LC-MS-MS/MS,LC-MS/MS,LC-MS/MS,LC-MS/MS |
| Quantification Technique | LC-ESI-MS,LC-ESI-MS,LC-ESI-MS,NA,NA,NA |
| Labelled/Label Free | Label Free,Label Free,Label Free,Label Free,Label Free,Label Free |
| FDR | NA,NA,NA,FDR 1 %,FDR 1 %,NA |
| CancerPDF_ID | CancerPDF_ID1483, CancerPDF_ID1512, CancerPDF_ID2672, CancerPDF_ID12339, CancerPDF_ID12671, CancerPDF_ID12698, |
| p-Value | NA,NA,NA,NA,NA,"0.813,less than 0.05,0.796" |
| Software | MASCOT(v. 2.2.01),MASCOT(v. 2.2.01),MASCOT(v. 2.2.01),SEQUEST and Maxquant,"Maxquant,Proteome Discoverer",Proteome Discoverer |
| Length | 10,10,10,10,10,10 |
| Cancer Type | Colorectal cancer,Colorectal cancer,Normal,Melanoma,Melanoma,Breast cancer |
| Database | SwissProt Database,SwissProt Database,SwissProt Database,SwissProt Database,SwissProt Database,SwissProt Database |
| Modification | NA,Oxidation of Met,NA,NA,NA,NA |
| Number of Patients | 30 patients and 30 healthy controls,30 patients and 30 healthy controls,27 healthy individuals,8 cancer samples and 4 healthy samples,8 cancer samples and 4 healthy samples," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)." |
| Regulation | NA,NA,NA,"Present in 8 cancer samples out of 8 cancer samples. ,Present in 4 healthy samples out of 4 healthy samples.","Present in 8 cancer samples out of 8 cancer samples. ,Present in 4 healthy samples out of 4 healthy samples.","Upregulated with the fold change of 1.02 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 1.13, Upregulated in BC vs healthy with 1.024 fold change" |
| Validation | Leave One out Cross validation,Leave One out Cross validation,Leave One out Cross validation,na,NA,NA |
| Sensitivity | NA,NA,NA,NA,NA,NA |
| Specificity | NA,NA,NA,NA,NA,NA |
| Accuracy | NA,NA,NA,NA,NA,NA |
| Peptide Atlas | NA |
| IEDB | |