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Details of CancerPDF entry with Sequence SSYSKQFTSSTSYNRGDSTFESKSY
Primary information
sequence IDSeq_7754
Peptide sequenceSSYSKQFTSSTSYNRGDSTFESKSY
CancerPDF_ID CancerPDF_ID1261, CancerPDF_ID12726,
PMID21136997,27058005
Protein NameFibrinogen alpha,Fibrinogen alpha chain
UniprotKB Entry NameFIBA_HUMAN,FIBA_HUMAN
FluidSerum,Serum
M/Z2843.25221,2931.376
Charge1,NA
Mass (in Da)NA,NA
fdrNA,NA
Profiling TechniqueLC-MS,MALDI-TOF
Peptide Identification techniqueLC-MS-MS/MS,LC-MS/MS
Quantification TechniqueLC-ESI-MS,NA
Labelled/Label FreeLabel Free,Label Free
FDR0.001,NA
CancerPDF_ID CancerPDF_ID1261, CancerPDF_ID12726,
p-Value8.90E-05,"0.139,0.997,0.387"
SoftwareMASCOT(v. 2.2.01),Proteome Discoverer
Length25,25
Cancer TypeColorectal cancer,Breast cancer
DatabaseSwissProt Database,SwissProt Database
ModificationNA,NA
Number of Patients30 patients and 30 healthy controls," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)."
RegulationDifferentially expressed between cancer vs normal,"Upregulated with the fold change of 0.79 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 1.00, Upregulated in BC vs healthy with 1.128 fold change"
ValidationLeave One out Cross validation,NA
Sensitivity0.898,NA
Specificity0.946,NA
Accuracy0.917,NA
Peptide AtlasNA
IEDB