| Primary information |
|---|
| sequence ID | Seq_4221 |
| Peptide sequence | KITHRIHWESASLLR |
| CancerPDF_ID | CancerPDF_ID9477, CancerPDF_ID12707, |
| PMID | 26379225,27058005 |
| Protein Name | Complement C3,Complement C3 |
| UniprotKB Entry Name | CO3_HUMAN,CO3_HUMAN |
| Fluid | Plasma,Serum |
| M/Z | 1847.04,1847.095 |
| Charge | NA,NA |
| Mass (in Da) | NA,NA |
| fdr | NA,NA |
| Profiling Technique | MALDI-TOF,MALDI-TOF |
| Peptide Identification technique | MALDI-TOF/TOF,LC-MS/MS |
| Quantification Technique | NA,NA |
| Labelled/Label Free | Label Free,Label Free |
| FDR | NA,NA |
| CancerPDF_ID | CancerPDF_ID9477, CancerPDF_ID12707, |
| p-Value | NA,"0.161,0.206,less than 0.05" |
| Software | MASCOT (v 2.3),Proteome Discoverer |
| Length | 15,15 |
| Cancer Type | Colorectal cancer,Breast cancer |
| Database | UniprotKB,SwissProt Database |
| Modification | NA,NA |
| Number of Patients | "94 patients with CRC, 23 with liver metastasis from CRC (histologically defined) and 34 subjects, which underwent colonoscopy and resulted negative"," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)." |
| Regulation | "Low expression in control, adenoma, early,late CRC and much more lower in liver metastasis group.","Upregulated with the fold change of 1.26 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 1.30, Upregulated in BC vs healthy with 1.623 fold change" |
| Validation | NA,NA |
| Sensitivity | NA,NA |
| Specificity | NA,NA |
| Accuracy | NA,NA |
| Peptide Atlas | NA |
| IEDB | 533899
|