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Details of CancerPDF entry with Sequence KHNLGHGHKHERDQGHGHQR
Primary information
sequence IDSeq_4200
Peptide sequenceKHNLGHGHKHERDQGHGHQR
CancerPDF_ID CancerPDF_ID9491, CancerPDF_ID12752,
PMID26379225,27058005
Protein NameKininogen-1,Kininogen-1
UniprotKB Entry NameKNG1_HUMAN,KNG1_HUMAN
FluidPlasma,Serum
M/Z2365.22,2365.208
ChargeNA,NA
Mass (in Da)NA,NA
fdrNA,NA
Profiling TechniqueMALDI-TOF,MALDI-TOF
Peptide Identification techniqueMALDI-TOF/TOF,LC-MS/MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDRNA,NA
CancerPDF_ID CancerPDF_ID9491, CancerPDF_ID12752,
p-ValueNA,"less than 0.01,0.000,less than 0.05"
SoftwareMASCOT (v 2.3),Proteome Discoverer
Length20,20
Cancer TypeColorectal cancer,Breast cancer
DatabaseUniprotKB,SwissProt Database
ModificationNA,NA
Number of Patients"94 patients with CRC, 23 with liver metastasis from CRC (histologically defined) and 34 subjects, which underwent colonoscopy and resulted negative"," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)."
Regulation"Low expression in control and liver metastatis group as comapred to adenoma, early,late CRC group.","Upregulated with the fold change of 1.62 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 1.87, Upregulated in BC vs healthy with 1.340 fold change"
ValidationNA,NA
SensitivityNA,NA
SpecificityNA,NA
AccuracyNA,0.742
Peptide AtlasNA
IEDB