| Primary information |
|---|
| sequence ID | Seq_3486 |
| Peptide sequence | HNLGHGHKHERDQGHGHQ |
| CancerPDF_ID | CancerPDF_ID3231, CancerPDF_ID8616, CancerPDF_ID8642, CancerPDF_ID12749, |
| PMID | 21136997,26705257,24416269,27058005 |
| Protein Name | Kininogen-1,Isoform HMW of kininogen-1 (KNG1) precursor,"Kininogen L,high MW",Kininogen-1 |
| UniprotKB Entry Name | KNG1_HUMAN,KNG1_HUMAN,KNG1_HUMAN,KNG1_HUMAN |
| Fluid | Plasma,Serum,Plasma,Serum |
| M/Z | 2079.9596,2082.04,2080.98,2081.006 |
| Charge | 1,NA,NA,NA |
| Mass (in Da) | NA,NA,NA,NA |
| fdr | NA,NA,NA,NA |
| Profiling Technique | LC-MS,MALDI-TOF,MALDI-TOF,MALDI-TOF |
| Peptide Identification technique | LC-MS-MS/MS,LC-ESI-MS/MS,MS/MS,LC-MS/MS |
| Quantification Technique | LC-ESI-MS,NA,Affinity Chromatography,NA |
| Labelled/Label Free | Label Free,Label Free,Label Free,Label Free |
| FDR | NA,NA,NA,NA |
| CancerPDF_ID | CancerPDF_ID3231, CancerPDF_ID8616, CancerPDF_ID8642, CancerPDF_ID12749, |
| p-Value | NA,1.00E-06,less than 0.05,"less than 0.01,0.242,less than 0.05" |
| Software | MASCOT(v. 2.2.01),ClinProTools,MASCOT and Markerview software version 1.2,Proteome Discoverer |
| Length | 18,18,18,18 |
| Cancer Type | Normal,Breast cancer,Cervical cancer,Breast cancer |
| Database | SwissProt Database,Uniprot protein sequence Database,NA,SwissProt Database |
| Modification | NA,NA,NA,NA |
| Number of Patients | 27 healthy individuals,96 Breast Cancer patients and 64 healthy controls,67 patients and 4 healthy," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)." |
| Regulation | NA,Upregulated in cancer as compare to normal control with fold change of 1.9,Differential expression,"Upregulated with the fold change of 0.43 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 0.71, Upregulated in BC vs healthy with 1.565 fold change" |
| Validation | Leave One out Cross validation,NA,NA,NA |
| Sensitivity | NA,NA,NA,NA |
| Specificity | NA,NA,NA,NA |
| Accuracy | NA,NA,NA,NA |
| Peptide Atlas | NA |
| IEDB | |