| Primary information |
|---|
| sequence ID | Seq_2828 |
| Peptide sequence | GLEEELQFSLGSK |
| CancerPDF_ID | CancerPDF_ID887, CancerPDF_ID1918, CancerPDF_ID9466, CancerPDF_ID9618, |
| PMID | 19795908,21136997,26379225,21533267 |
| Protein Name | Complement C4-B,Complement C4-B,Complement C4-A/Complement C4-B,Complement C4-B |
| UniprotKB Entry Name | CO4B_HUMAN,CO4B_HUMAN,"CO4A_HUMAN,CO4B_HUMAN",CO4B_HUMAN |
| Fluid | Plasma,Serum,Plasma,Serum |
| M/Z | "718.86, 479.57",1435.71947,1436.72,718.84 |
| Charge | "2, 3",1,NA,2 |
| Mass (in Da) | NA,NA,NA,NA |
| fdr | NA,NA,NA,NA |
| Profiling Technique | LC-MS,LC-MS,MALDI-TOF,LC-MS |
| Peptide Identification technique | MALDI-TOF/TOF,LC-MS-MS/MS,MALDI-TOF/TOF,LC/MS/MS |
| Quantification Technique | LC-MRM (multiple reaction monitoring),LC-ESI-MS,NA,Multiple Reaction Monitoring |
| Labelled/Label Free | Labelled,Label Free,Label Free,Label Free |
| FDR | less than 7%,NA,NA,1.49 |
| CancerPDF_ID | CancerPDF_ID887, CancerPDF_ID1918, CancerPDF_ID9466, CancerPDF_ID9618, |
| p-Value | NA,NA,NA,NA |
| Software | FlexAnalysis 3.0 and Biotools 3.0 software,MASCOT(v. 2.2.01),MASCOT (v 2.3),MASCOT |
| Length | 13,13,13,13 |
| Cancer Type | Ductal adenocarcinoma of the pancreas (DAP),Colorectal cancer,Colorectal cancer,Lung adenocarcinoma |
| Database | NCBI refseq Protein Database,SwissProt Database,UniprotKB,Swissprot Database (57.4) |
| Modification | NA,NA,NA,NA |
| Number of Patients | "42 normal, 28 patients",30 patients and 30 healthy controls,"94 patients with CRC, 23 with liver metastasis from CRC (histologically defined) and 34 subjects, which underwent colonoscopy and resulted negative",62 lung adenocarcinoma and 30 healthy control |
| Regulation | NA,NA,Lower intensity in liver metastasis than control groups and an opposite trend in adenoma and CRC group.,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal" |
| Validation | NA,Leave One out Cross validation,NA,MRM-based validation of 19 candidates |
| Sensitivity | NA,NA,NA,NA |
| Specificity | NA,NA,NA,NA |
| Accuracy | NA,NA,NA,NA |
| Peptide Atlas | PeptideAtlas |
| IEDB | 462022
462023
|