Welcome to Sequence Card of Peptide


Details of CancerPDF entry with Sequence EpGSpGENGApGQMGPRG
Primary information
sequence IDSeq_1912
Peptide sequenceEPGSPGENGAPGQMGPRG
CancerPDF_ID CancerPDF_ID4773, CancerPDF_ID10820,
PMID24982608,21805675
Protein NameCollagen alpha-1(I) chain,Collagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN,CO1A1_HUMAN
FluidUrine,Urine
M/ZNA,1742.7158
ChargeNA,NA
Mass (in Da)NA,NA
fdrNA,NA
Profiling TechniqueNano-LC-MS,MALDI-TOF
Peptide Identification techniqueMS/MS,MALDI-TOF-MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDR0.01,1
CancerPDF_ID CancerPDF_ID4773, CancerPDF_ID10820,
p-ValueNA,NA
Software"GPM search engine, MASCOT",NA
Length18,18
Cancer TypeOvarian cancer,Muscle-invasive bladder cancer
DatabaseIPI 3.71 Human Database ,SwissProt Database
ModificationNA,"Oxidation: 2, 5, 11"
Number of Patients6 Ovarian cancer patients and 6 normal individuals,751 bladder cancer and 127 control
RegulationUniquely present in case of urine of ovarian cancer patients,Differentially expressed between cancer vs normal samples
ValidationNA,Mann-Whitney tests and areas under receiver-operator characteristic
SensitivityNA,NA
SpecificityNA,NA
AccuracyNA,NA
Peptide AtlasNA
IEDB
Primary information
sequence IDSeq_2048
Peptide sequenceEpGSPGENGApGQMGPRG
CancerPDF_ID CancerPDF_ID3629,
PMID27026199
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr1725.74
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3629,
p-Valueless than 0.01
SoftwareProteome Discoverer 1.2
Length18
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationp:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA
Primary information
sequence IDSeq_2049
Peptide sequenceEpGSpGENGApGQMGPRG
CancerPDF_ID CancerPDF_ID3461, CancerPDF_ID3632,
PMID27026199,27026199
Protein NameCollagen alpha-1(I) chain,Collagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN,CO1A1_HUMAN
FluidUrine,Urine
M/ZNA,NA
ChargeNA,NA
Mass (in Da)NA,NA
fdr1741.73,1741.73
Profiling Technique"CE-MS, Micro-TOF-MS","CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS,MS-MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDRNA,NA
CancerPDF_ID CancerPDF_ID3461, CancerPDF_ID3632,
p-Valueless than 0.05,8.70E-04
SoftwareProteome Discoverer 1.2,Proteome Discoverer 1.2
Length18,18
Cancer TypeBladder cancer,Bladder cancer
DatabaseUniprot Human non-redundant Database,Uniprot Human non-redundant Database
Modificationp:Hydroxy-Proline,p:Hydroxy-Proline
Number of Patients451 for training (341 patients and 110 normal) and 270 for testing(168 primary UBC patients and 102 normal controls);, 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between primary UBC and normal individual,Differentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation,Independent Validation
SensitivityFor testing dataset 91%,For testing dataset 88%
SpecificityFor testing dataset 68%,For testing dataset 51%
AccuracyFor testing dataset 76%,NA
Peptide AtlasNA
IEDB
Primary information
sequence IDSeq_2050
Peptide sequenceEpGSpGENGApGQmGPRG
CancerPDF_ID CancerPDF_ID3637,
PMID27026199
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr1757.73
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3637,
p-Valueless than 0.01
SoftwareProteome Discoverer 1.2
Length18
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationm: Oxidized-Methionine; p:Hydoxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA