Primary information |
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sequence ID | Seq_1186 |
Peptide sequence | DDPDAPLQPVTPLQLFEGRRN |
CancerPDF_ID | CancerPDF_ID901, CancerPDF_ID1902, CancerPDF_ID4024, CancerPDF_ID8563, CancerPDF_ID12677, |
PMID | 19795908,21136997,23891694,23667664,25168216 |
Protein Name | Complement C4-B,Complement C4-B,C4A(Complement C4-A) variant protein,Complement C3f,Complement C4 |
UniprotKB Entry Name | CO4B_HUMAN,CO4B_HUMAN,C4A_HUMAN,CO3_HUMAN,CO4A_HUMAN |
Fluid | Plasma,Serum,Human milk,Serum,Serum |
M/Z | 793.4,2377.20262,NA,2377.2,NA |
Charge | 3,1,NA,1,NA |
Mass (in Da) | NA,NA,NA,2379.64,NA |
fdr | NA,NA,2377.2,NA,2377.2 |
Profiling Technique | LC-MS,LC-MS,MALDI-TOF,MALDI-TOF,LC-MS |
Peptide Identification technique | MALDI-TOF/TOF,LC-MS-MS/MS,LC-MS/MS,FT-ICR MS/MS + nano-HPLC,LC-MS/MS |
Quantification Technique | LC-MRM (multiple reaction monitoring),LC-ESI-MS,NA,NA,NA |
Labelled/Label Free | Labelled,Label Free,Label Free,Label Free,Label Free |
FDR | less than 7%,NA,NA,NA,NA |
CancerPDF_ID | CancerPDF_ID901, CancerPDF_ID1902, CancerPDF_ID4024, CancerPDF_ID8563, CancerPDF_ID12677, |
p-Value | NA,NA,7.60E-03,NA,2.99E_09 |
Software | FlexAnalysis 3.0 and Biotools 3.0 software,MASCOT(v. 2.2.01),MASCOT,MASCOT,MASCOT |
Length | 21,21,21,21,21 |
Cancer Type | Ductal adenocarcinoma of the pancreas (DAP),Colorectal cancer,Normal,"Breast cancer, Lung cancer, Rectal cancer",Renal cell carcinaoma |
Database | NCBI refseq Protein Database,SwissProt Database,SwissProt Database and UniProt Database (release2013_5),NA,SwissProt Database |
Modification | NA,NA,NA,NA,NA |
Number of Patients | "42 normal, 28 patients",30 patients and 30 healthy controls,NA,"Breast Cancer =84, lung cancer= 70, Rectal cancer = 30patients; 500 healthy","30 RCC patients and 30 healthy controls for training dataset and 6 RCC patients, 6 control in independent validation dataset" |
Regulation | NA,NA,Downregulated 3 fold in Pre-term case as compare to normal,NA,Upregulated in cancer v/s Normal |
Validation | NA,Leave One out Cross validation,NA,NA,Independent validation |
Sensitivity | NA,NA,NA,NA,100 % (for 19 peptide signatures) |
Specificity | NA,NA,NA,NA,NA |
Accuracy | NA,NA,NA,NA,AUC : 0.891 |
Peptide Atlas | NA |
IEDB | |