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The total number entries retrieved from this search are 28
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Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
20743-Hydroxyanthranilic acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2088Aspartate aminotransferase to white blood cell count ratio (AWR)OthersHumanAWR > 5.2 was an adverse predictor of DFS and OS in HCC after hepatectomy PrognosticHCC patients with AWR >5.2 v/s HCC patients with AWR <5.2; predict survival of patients p < 0.01Blood27057915
2269Phosphoserine aminotransferaseProteinHumanUpregulated in recurrence HCC than non-recurrence HCC (with fold change 3.8) PrognosticEarly recurrence v/s No recurrence HCC p < 0.05Tissue17391314
2278Cyclophilin B (Peptidyl-prolyl cis-trans isomerase B)ProteinHumanDownregulated in recurrence HCC than non-recurrence HCC (with fold change 0.53) PrognosticEarly recurrence v/s No recurrence HCC p < 0.05Tissue17391314
2286Glutamine amidotransferaseProteinHumanDownregulated in recurrence HCC than non-recurrence HCC (with fold change 0.69) PrognosticEarly recurrence v/s No recurrence HCC p < 0.05Tissue17391314
2333RANRNAsHumanUpregulated in HCCs with PVI in comparison with HCCs without PVI (with Fisher ratio 1.14) PrognosticHCC with PVI v/s HCC without PVI p < 0.05Tissue17088983
2379Alanine:glyoxylate aminotransferaseRNAsHumanUpregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2386TransferrinRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2397Acyl-coenzyme A:cholesterol acyltransferase 1RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2399CTP:phosphocholinecytidyl transferaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2410Glutathione S-transferase θ1RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2411Glutathione S-transferaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2412Glutathione S-transferase M3RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2413Glutathione S-transferase θ2RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2468hnRNP K, HSP70RY, Lamin B1, 40S ribosomal protein SA, FTCD, SOD, Arginase, SMP-30, P5C dehydrogenase, Transitional endoplasmic reticulum ATPase, Ubiquitin carboxyl-terminal hydrolase 5, Thiosulfate sulfurtransferase (Rhodanese), Betaine-himocysteine S-methyltransferase, NCC27, FGB, RACK1, PDI, SARDHProteinHumanDifferentially expressed (hnRNP K, HSP70 RY, Lamin B1, 40S ribosomal protein SA, Transitional endoplasmic reticulum ATPase, Ubiquitin carboxyl-terminal hydrolase 5, Rhodanese, Betaine-himocysteine S-methyltransferase, NCC27, Fibrinogen β chain, RACK1 are Upregulated and rest 12 are Downregulated) DiagnosticHBV associated HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2496Guanidinoacetate N-methyltransferaseProteinHumanDownregulated in HCC than non tumor (with mean ratio of nearly 5.3 +/- 8.6) DiagnosticHCC v/s non-tumor p < 0.05Tissue12481271
2497Catechol O-methyltransferaseProteinHumanDownregulated in HCC than non tumor (with mean ratio of nearly 3.2 +/- 3.8) DiagnosticHCC v/s non-tumor p < 0.05Tissue12481271
2504CDC28 protein kinase2, CDC27HS protein, Integrin beta 4, Desmoplakin 1/2, Procollagen C proteinase, platelet derived growth factor, cytidine deaminase, aminoacyalse1, Betaine homocysteine S-methyltransferase, methylenetetrahydrofolate dehydrogease, metalloproteinase inhibitor1, aldehyde oxidase, metRNAsHumanDiffrenetially expressed in HCV and HBV associated HCC v/s non-tumor DiagnosticHCV and HBV associated HCC v/s non-tumor p < 0.01Tissue11973655
2505Lactate dehydrogenase, aldehyde oxidase, nucleoside diphosphate kinase, alpha 1 catenin, beta catenin, transforming protein rho B, IgG, IgGK, IgG3, IgG1, IgG1K, IgA1, IgHA, IgG1-Fc, Collagen - alpha 1 subunit, c-jun N-terminal kinase 2, ADP/ATP carrier protein, Progression receptor associated proteiRNAsHumanDiffrenetially expressed in cirrhotic v/s non-cirrhotic Diagnosticcirrhotic v/s non-cirrhotic p < 0.01Tissue11973655
2506Zinc finger protein, integrin alpha 6, hepatoma derived growth factor, TGF beta induced, Macrophage inhibitory cytokine 1, lymphocyte antigen, aldehyde oxidase, c-myc purine binding transcription factor puf, plasminogen, vitronectin, hemoglobin alpha subunit, cytosolic superoxide dismutase, methylenRNAsHumanDiffrenetially expressed in moderately differentiated HCC v/s poorly differentiated HCC Diagnosticmoderately differentiated HCC v/s poorly differentiated HCC p < 0.01Tissue11973655
2525Cytoplasmic dynein light chain, Hepatoma-derived growth factor, Ribosomal protein L6, glutathioneS-transferase, Fibronectin, Ras homolog gene family member B, TR3 orphan receptor, c-myc transcription factor (puf), MHC-class ICRNAsHumanUpregulated in HCC than non-tumorous tissue ( with average ratio more than 2) DiagnosticHCC v/s non-tumor NATissue11283847
2527transgelin 2RNAsHumanUpregulated in HCC than non-tumorous tissue DiagnosticHCC v/s non-tumor p < 0.05Tissue15756260
2551Isocitrate dehydrogenase [NADP] (cytoplasmic), Fumarate hydratase (mitochondrial), Enoyl-CoA hydratase (mitochondrial), Betaine-homocysteine S-methyltransferase, Serotransferrin precursorProteinHumanDownregulated in well-differentiated HCC (with 2 fold change) DiagnosticHCC v/s non-tumor p < 0.05Tissue15852300
2553Keratin type I cytoskeletal 10, Catalase, Aldehyde dehydrogenase (mitochondrial), GlutathioneS-transferase A1, Antioxidant protein 2, Isocitrate dehydrogenase [NADP] (cytoplasmic), Formiminotransferase-cyclodeaminase, Carbonic anhydrase I, Fructose bisphosphate aldolase B, Arginase 1, Fructose-1, 6-ProteinHumanDownregulated in poorly-differentiated HCC (with 2 fold change) DiagnosticHCC v/s non-tumor p < 0.05Tissue15852300
2554sterol-C5-desaturase, Peroxisomal phytanoyl-CoA alpha-hydroxylase, Homo sapiens clone 23915, Osteopontin 5/6 0, Full-length cDNA clone ZD66D02, Senescence-associated epithelial membrane protein(SEMP1), Human DNA topoisomerase II (top2) mRNA, Homo sapiens lysosomal membrane glycoprotein-2 (LAMP2), HuRNAsHumanUpregulated in HCC than non-tumor DiagnosticTumor v/s normal NATissue12136251
2562galectin-3,serine/threonine kinase, translation factor eIF- 4A, -4B, -3, fibroblast growth factor receptor, and ri- bosomal protein L35ARNAsHumanUpregulated in HCC DiagnosticHCC v/s non-tumor Tissue12521301
2580Dystrophin, Homolog to tubulin beta chain, Zinc finger protein 337, Friedreich ataxia region gene X123, Fibronectin (Alt. Splice 1), Zinc finger protein 9, Metallothionein IV, Poly(rC) binding protein 3, KIAA0426 gene product, Hypothetical protein FLJ13910, RAN binding protein 2 like 1, S100 calciumRNAsHumanDownregulated in L1 than L0 (with fisher ratio more than 9.74) Prognostic non-tumorous livers L1 (with HCV infection) v/s and L0 (without HCV infection) ; associated with invasion or metastsis P = 0.001Tissue15710396
2581Cystatin C, Prolylcarboxypeptidase (angiotensinase C), Lysyl-tRNA synthetase, Voltage-dependent anion channel 3, Protective protein for beta-galactosidase (cathepsin A), Interferon gamma-inducible protein 30, Signal sequence receptor delta, Thioredoxin-related transmembrane protein, Cathepsin D, RasRNAsHumanUpregulated in L1 than L0 (with Fisher ratio more than 8.9) Prognostic non-tumorous livers L1 (with HCV infection) v/s and L0 (without HCV infection) ; associated with invasion or metastsis P = 0.001Tissue15710396

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