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The total number entries retrieved from this search are 13
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Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
21242-pyrocatechuic acidMetabolitesMiceUpregulated in AFLD Potential Predictive *Serum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled Serum24171385
2232CCAT2LncRNAHumanUpregulated in HCC DiagnosticHCC v/s Normal p < 0.05Tissue27347113
2234CCAT2LncRNAHumanUpregulated in HCC PrognosticHCC v/s Normal; associated with poor survival in HCC patients p < 0.01Tissue28280353
2238CCAT1LncRNAHumanUpregulated in HCC PrognosticHCC v/s Normal; correlated with tumor size, microvascular invasion and poor prognosis p < 0.001Tissue25884472
2268LIMK1, CENPE, FZD2, ENO2, ITGA9, COPA, KIAA0660, GTF2H1, VPS41, RGS20, MATK, STOML1, BASP1, EPB42, ALDH3B2, MEL, CAT56, RAB3A, PSCD3, PLD2, ADCYAP1R1, ALDH3B1, RHD, CSF3R, KIAA0063, KIAA0296, LRP6, ENO3, CTRB1, YES1, IncytePD:1404153, GYS1, MDFI, GABRE, IncytePD:2685601, CD3Z, DTYMK, SPTBN2, IncytePRNAsHumanUpregulated in PT than PN (with 3 fold change) DiagnosticMetastatic HCC v/s Primary HCC p < 0.01Tissue12640447
2470HSP27, Enoyl-CoA hydratase, Tubulin β chain, Galactose kinase, Ubiquinol-cytochrome C reductase complex core protein I, Annexin V, P-PST, Ribosome binding protein, Fumarylacetoacetase, ALDH, Catalase,ProteinHumanDifferentially expressed (P-PST, Ribosome binding protein, Fumarylacetoacetase, Catalase and ALDH are Downregulated and rest 6 are Upregulated) in HCC tumor v/s non-tumorous DiagnosticBoth HBV- and HCV associated HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2471Protein disulfide isomerase ER-60, PRBP, Tropomyosin 3, ATP synthase, Dihydropipoamide dehydrogenase, FABP, Cathepsin B1,ProteinHumanDifferentially expressed (FABP, Cathepsin B1 are Downregulated and rest 5 are Upregulated) in HCC tumor v/s non-tumorous Diagnosticboth (HBV and HCV) negative HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2495Cathepsin DProteinHumanDownregulated in HCC than non tumor (with mean ratio of nearly 3.5 +/- 3.3) DiagnosticHCC v/s non-tumor p < 0.05Tissue12481271
2497Catechol O-methyltransferaseProteinHumanDownregulated in HCC than non tumor (with mean ratio of nearly 3.2 +/- 3.8) DiagnosticHCC v/s non-tumor p < 0.05Tissue12481271
2502CAPG, OCC-1, EED, RPLP0, RPLP0P2, AP1S2, RRAGD, PFDN4, CCDC104, C7orf28B, PSIP1, LPCAT1, FSCN3, RAB24, ZNF446, SEC11B, ZNF586, SCNM1, SF3A1, RUFY1, TRIM55, GOLGA4, GPATCH4, THOP1, TUBB2C, PHLDB3, FAM104A, FASTK, EIF2AK4, ZFP41, PRKRIP1, DSTN, PHIP, NUCKS1, TNRC8, CCDC132, EPRS, HIST1H4C, CDCA8,RNAsHumanUpregulated in HCV related HCC than HCV related non-HCC (With 3-fold change) DiagnosticHCV related HCC v/s HCV related non-HCC p < 0.01Tissue19821982
2505Lactate dehydrogenase, aldehyde oxidase, nucleoside diphosphate kinase, alpha 1 catenin, beta catenin, transforming protein rho B, IgG, IgGK, IgG3, IgG1, IgG1K, IgA1, IgHA, IgG1-Fc, Collagen - alpha 1 subunit, c-jun N-terminal kinase 2, ADP/ATP carrier protein, Progression receptor associated proteiRNAsHumanDiffrenetially expressed in cirrhotic v/s non-cirrhotic Diagnosticcirrhotic v/s non-cirrhotic p < 0.01Tissue11973655
2553Keratin type I cytoskeletal 10, Catalase, Aldehyde dehydrogenase (mitochondrial), GlutathioneS-transferase A1, Antioxidant protein 2, Isocitrate dehydrogenase [NADP] (cytoplasmic), Formiminotransferase-cyclodeaminase, Carbonic anhydrase I, Fructose bisphosphate aldolase B, Arginase 1, Fructose-1, 6-ProteinHumanDownregulated in poorly-differentiated HCC (with 2 fold change) DiagnosticHCC v/s non-tumor p < 0.05Tissue15852300
2581Cystatin C, Prolylcarboxypeptidase (angiotensinase C), Lysyl-tRNA synthetase, Voltage-dependent anion channel 3, Protective protein for beta-galactosidase (cathepsin A), Interferon gamma-inducible protein 30, Signal sequence receptor delta, Thioredoxin-related transmembrane protein, Cathepsin D, RasRNAsHumanUpregulated in L1 than L0 (with Fisher ratio more than 8.9) Prognostic non-tumorous livers L1 (with HCV infection) v/s and L0 (without HCV infection) ; associated with invasion or metastsis P = 0.001Tissue15710396

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