Mutation-based Significant genes
The pupose of this tool is to find out the significance of a gene mutation in terms of IC50 for given drugs. This tool is based on the difference of IC50 of mutated and normal cell lines for that particular gene.The occurance of mutation in every single gene may lead to resistance or sensitivity.

Please select field you wish to DISPLAY:

 17AAG  AEW541  AZD0530  AZD6244  Erlotinib
 Irinotecan   L685458   Lapatinib   LBW242   Nilotinib
 PF2341066   PHA665752   PLX4720   RAF265   Sorafenib
 TAE684   TKI258   Topotecan   ZD6474