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VTQAASRVCDKMKILRGVCKKIMRTFLRR details
Primary information
ID antitb_1355,
Name10585872
N-Terminal modificationNKLF1
C-Terminal ModificationVTQAASRVCDKMKILRGVCKKIMRTFLRR
Chemical ModificationFree
Linear/CyclicFree
LengthInternal disulphide bond at residue between 9-13
ChiralityCyclic
Nature29
SourceL
SpeciesNatural
StrainPig cytolytic lymphocytes
Inhibition ConcentrationMycobacterium tuberculosis
In Vitro/ In vivoMycobacterium tuberculosis H37Rv ATCC 25619
Cell LineIC90 = 30 μM
Inhibition ConcentrationIn vitro
Sequence1999
CytotoxicityHuman erythroleukaemia cell line K562
In vivo ModelNA
Lethal Dose31 % cytolytic activity in range of 3 -7 μM peptide concentration
Immune ResponceNA
Mechanism of ActionNA
TargetNA
Combination TherapyNA
Other activitiesNA
PMIDNA
Year of PublicationAntibacterial against bacillus megaterium, E.coli, P.aeuroginosaand S.aureus
Tertiary Structure
(Technique)
Not Predicted),