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SEFAYGSFVRTVSLPVGADE details
Primary information
ID antitb_1266,
Name24434326
N-Terminal modificationF91
C-Terminal ModificationSEFAYGSFVRTVSLPVGADE
Chemical ModificationFree
Linear/CyclicFree
LengthNone
ChiralityLinear
Nature20
SourceL
SpeciesProtein Derived
StrainFrom 16kDa antigen
Inhibition ConcentrationNone
In Vitro/ In vivoNone
Inhibition ConcentrationIn vivo
Sequence2013
CytotoxicityNA
In vivo ModelNA
Lethal DoseNA
Immune ResponceFemale BALB/c mice (6-8 wk, 20±2 g)
Mechanism of Action20 nmol
TargetIt promotes the maturation of MHC-II and elicit secretion of IFN-Î¥ and also induce the expression of CD80, CD86 and CD40 co-stimulatory molecules and activate DCs to produce IL-6 and IL-12.
Combination TherapyNA
Other activitiesNA
PMIDNone
Year of PublicationNA
Tertiary Structure
(Technique)
Not Predicted),
Primary information
ID antitb_1267,
Name24434326
N-Terminal modificationL91
C-Terminal ModificationSEFAYGSFVRTVSLPVGADE
Chemical ModificationFree
Linear/CyclicFree
LengthConjugated to TLR2-ligand Pam2Cys
ChiralityLinear
Nature20
SourceL
SpeciesProtein Derived
StrainFrom 16kDa antigen
Inhibition ConcentrationNone
In Vitro/ In vivoNone
Inhibition ConcentrationIn vivo
Sequence2013
CytotoxicityNA
In vivo ModelNA
Lethal DoseNA
Immune ResponceFemale BALB/c mice (6-8 wk, 20±2 g)
Mechanism of Action20 nmol
TargetIt promotes the maturation of MHC-II and elicit secretion of IFN-Î¥ and also induce the expression of CD80, CD86 and CD40 co-stimulatory molecules and activate DCs to produce IL-6 and IL-12.
Combination TherapyNA
Other activitiesNA
PMIDNone
Year of PublicationNA
Tertiary Structure
(Technique)
Not Predicted),