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LLKKLLKKC details
Primary information
ID antitb_1239,
Name24314557
N-Terminal modification(LLKK)2C
C-Terminal ModificationLLKKLLKKC
Chemical ModificationFree
Linear/CyclicFree
LengthNone
ChiralityLinear
Nature9
SourceL
OriginCationic
SpeciesSynthetic
Inhibition ConcentrationMycobacterium smegmatis
In Vitro/ In vivoMycobacterium smegmatis (ATCC No. 14468)
Cell LineMIC = 125 mg/L
Inhibition ConcentrationIn vitro
Sequence2014
CytotoxicityRat red blood cells (rRBCs)
In vivo ModelNA
Lethal DoseVery low, i.e. 50% hemolysis concentration (HC50) > 1000 mg/L
Immune ResponceNone
Mechanism of ActionNA
TargetNA
Combination TherapyMembrane-lytic mechanism
Other activitiesCell envelope
PMIDNone
Year of PublicationAntibacterial
Tertiary Structure
(Technique)
Not Predicted),