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FWGALAKGALKLIGPGSLFSSFSKKD details |
| Primary information | |
|---|---|
| ID | antitb_1189, |
| Name | 25019413 |
| N-Terminal modification | Pin2 [GPG] |
| C-Terminal Modification | FWGALAKGALKLIGPGSLFSSFSKKD |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 26 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Strain | Amino acid substitution at one postion of Pin2 (P at 14 by GPG) |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis H37Rv |
| Cell Line | MIC = 80.1 ± 24.8 μg/ml or 29 ± 9 μM |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | RBC |
| In vivo Model | NA |
| Lethal Dose | Hemolysis ( IC-50 = 46.6 [34–64] ) |
| Immune Responce | None |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | Cell wall disruption |
| Other activities | Cell wall |
| PMID | None |
| Year of Publication | Anti-bacterial (E. coli, S. aureus) |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1190, |
| Name | 25019413 |
| N-Terminal modification | Pin2 [GPG] |
| C-Terminal Modification | FWGALAKGALKLIGPGSLFSSFSKKD |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 26 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Strain | Amino acid substitution at one postion of Pin2 (P at 14 by GPG) |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis muti-drug resistant strain (MDR) clinical isolate |
| Cell Line | MIC = 48.1 μg/ml or 17.4 μM |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | RBC |
| In vivo Model | NA |
| Lethal Dose | Hemolysis ( IC-50 = 46.6 [34–64] ) |
| Immune Responce | None |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | Cell wall disruption |
| Other activities | Cell wall |
| PMID | None |
| Year of Publication | Anti-bacterial (E. coli, S. aureus) |
| Tertiary Structure (Technique) | Not Predicted), |