Primary information |
---|
ID | antitb_1501 |
Peptide Name | Sansanmycins A (Ssa) |
Sequence | not available |
N-terminal Modification | NA |
C-terminal Modification | NA |
Chemical Modification | NA |
Linear/ Cyclic | Branched cyclic |
Length | 0 |
Chirality | D |
Nature | Cationic |
Source | Natural |
Origin | Derived from Streptomyces species |
Species | Mycobacterium tuberculosis |
Strain | Mycobacterium tuberculosis 2199 |
Inhibition Concentartion | IC50= 32 μg/ml |
In vitro/In vivo | In vitro |
Cell Line | NA |
Inhibition Concentartion | NA |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | Inhibit the MraY translocase present in the bacterial cell membrane |
Target | NA |
Combination Therapy | NA |
Other Activities | Antibacterial against E.coli, S.aureus, bacillus, pseudomonas |
Pubmed ID | 25681127 |
Year of Publication | 2015 |
3-D Structure | NA |