| Primary information |
|---|
| ID | antitb_1361 |
| Peptide Name | Pleurocidin |
| Sequence | GWGSFFKKAAHVGKHVGKAALTHYL |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 25 |
| Chirality | L |
| Nature | NA |
| Source | Natural |
| Origin | Pleuronectes americanus |
| Species | Mycobacterium smegmatis |
| Strain | Mycobacterium smegmatis |
| Inhibition Concentartion | MIC = 20 μg/ml |
| In vitro/In vivo | In vitro |
| Cell Line | None |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | 185 μM OF D-CYCLOSERINE DRUG + 5.2 μM OF Peptide reduces ~ 4 time MIC of drug |
| Other Activities | Antibacterial against P.aeruginosa, K.pneumoniae,S.aureus and C.albicans |
| Pubmed ID | 10898673 |
| Year of Publication | 2000 |
| 3-D Structure |  View in Jmol or Download Structure |