| Primary information |
|---|
| ID | antitb_1349 |
| Peptide Name | Tenecin 1 Fragment 33-43 |
| Sequence | YCNGKRVCVC |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Chemical Modification | Internal disulphide bond |
| Linear/ Cyclic | Cyclic |
| Length | 10 |
| Chirality | NA |
| Nature | NA |
| Source | Natural |
| Origin | Larvae of tenebrio molitor(beetle) |
| Species | Mycobacterium smegmatis |
| Strain | Mycobacterium smegmatis ATCC 612 |
| Inhibition Concentartion | MIC = >100 μg/ml |
| In vitro/In vivo | in vitro |
| Cell Line | Human erythrocyte |
| Inhibition Concentartion | NA |
| Cytotoxicity | None |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Membrane disruption as reported by membrane leaky assay |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | Antibacterial against MRSA, bacillus subtilis, E.coli, Shigella at 10-30 μg/ml |
| Pubmed ID | 9693108 |
| Year of Publication | 1998 |
| 3-D Structure | NA |