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Detailed description page of AntiTbPdb

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antitb_1115 details
Primary information
IDantitb_1115
Peptide NameSeq 46
SequenceRTKKWIVWI
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationNone
Linear/ CyclicLinear
Length9
ChiralityL
NatureCationic
SourceSynthetic
OriginNA
SpeciesMycobacterium tuberculosis
StrainMycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain
Inhibition ConcentartionMIC90 = 78.1 μM
In vitro/In vivoIn vitro
Cell LineTHP-1 cells
Inhibition ConcentartionNA
CytotoxicityFor THP-1 (infected wth M.tb) IC50 = 208.3 μM
In vivo ModelNone
Lethal DoseNA
Immune ResponseNA
Mechanism of ActionNA
TargetNA
Combination TherapyNone
Other ActivitiesAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)
Pubmed ID23478953
Year of Publication2013
3-D Structure View in Jmol or Download Structure