| Primary information |
|---|
| AHTPDB ID | 1088 |
| PMID | 23271625 |
| YEAR | 2013 |
| SEQUENCE | WPEAAELMMEVDP |
| LENGTH | 13 |
| MOL WT | 1517.73 |
| IC50 | 21.6 μM |
| pIC50 | ND |
| SOURCE | Fish (Tuna dark muscle) |
| TESTED ON | SHR |
| PURIFICATION | IEC, RP-HPLC, |
| ASSAY | Cushman and Cheung (1971), Yamamoto and others |
| BITTERNESS | ND |
| ISOELECTRIC POINT | 3.50 |
| SYSTOLIC BP DECREASE | 15 (approx) |
| Secondary information |
|---|
| Properties | Physico-Chemical details |
| STRUCTURE | |
| DSSP states | CCGGGTCCSSCCC |
| SMILES | N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)O |
| External Links to PDB, Swiss-Prot and IEDB |
|---|
| PDB exact | PDB partial | SP exact | SP partial | IEDB exact | IEDB partial |
| NA |
NA |
NA |
NA
from
TO
|
NA |
NA |
|
| Reference Informaiton |
|---|
| ARTICLE/REFERENCE | Review on the angiotensin-I-converting enzyme (ACE) inhibitor peptides from marine proteins. |
| AUTHORS/PRIMARY REFERENCE | He HL1, Liu D, Ma CB. |
| JOURNAL/EXTRA LINKS | Appl Biochem Biotechnol. 2013 Feb;169(3):738-49. |